This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Su, Min, Cao, Yan, Zhao, Li, Chai, Mei, Yang, Zhang, Zhang, Liu, Sun, Che, Yang: "LRRC19 expressed in the kidney induces TRAF2/6-mediated signals to prevent infection by uropathogenic bacteria." in: Nature communications, Vol. 5, pp. 4434, (2014) (PubMed).
Sun, Tang, Lin, Chen: "The WD40 repeat protein WDR26 binds G?? and promotes G??-dependent signal transduction and leukocyte migration." in: The Journal of biological chemistry, Vol. 286, Issue 51, pp. 43902-12, (2011) (PubMed).