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The glycoprotein encoded by VWF functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. 再加上，我们可以发VWF 抗体 (539) 和 VWF 蛋白 (21)和数多这个蛋白质的别的产品。
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Rat (Rattus) VWF ELISA Kit for Sandwich ELISA - ABIN367459
Baraka, Guemei, Gawad: Role of modulation of vascular endothelial growth factor and tumor necrosis factor-alpha in gastric ulcer healing in diabetic rats. in Biochemical pharmacology 2010
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Human VWF ELISA Kit for Sandwich ELISA - ABIN2703573
Ma, Su, Zhang, Ling, Yin, Bai, Ruan: The co-influence of VWD type 2B/2M mutations in the A1 domain and platelet GPIbα on the rate of cleavage to VWF by ADAMTS13. in Thrombosis research 2015
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Rat (Rattus) VWF ELISA Kit for Sandwich ELISA - ABIN416122
Imaoka, Sayama, Suzuki, Jindo, Sanbuissho: Effect of Hypertension on the Occurrence of Micro-hemorrhage in the Pancreatic Islet of Dahl Salt-sensitive Rats. in Journal of toxicologic pathology 2012
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Human VWF ELISA Kit for Sandwich ELISA - ABIN612793
Zimmerman, Ruggeri: von Willebrand disease. in Human pathology 1987
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Human VWF ELISA Kit for Sandwich ELISA - ABIN365425
Tong, Wan, Zhang, Duan, Tang, Chen, Tang, Su: Vascular endothelial cell injury partly induced by mesenteric lymph in heat stroke. in Inflammation 2014
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Human VWF ELISA Kit for Sandwich ELISA - ABIN2685886
Morton, Griffin, Pepper, Barnes: The interaction between collagens and factor VIII/von Willebrand factor: investigation of the structural requirements for interaction. in Thrombosis research 1984
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Rabbit VWF ELISA Kit for Competition ELISA - ABIN415967
Du, Wu, Qing, Wang, Liang, Yu, Tang: Systemic and flap inflammatory response associates with thrombosis in flap venous crisis. in Inflammation 2015
Rat (Rattus) VWF ELISA Kit for Competition ELISA - ABIN4948139
Murata, Miyake, Takahashi, Suzuki, Fujiwara, Sato, Inoue, Kobayashi, Kanamoto: Low-Dose Sodium Nitrite Fluid Resuscitation Prevents Lethality From Crush Syndrome by Improving Nitric Oxide Consumption and Preventing Myoglobin Cytotoxicity in Kidney in A Rat Model. in Shock (Augusta, Ga.) 2016
Human VWF ELISA Kit for Competition ELISA - ABIN4948138
Szpera-Go��dziewicz, Majcherek, Boruczkowski, Goździewicz, Dworacki, Wicherek, Bręborowicz: Circulating endothelial cells, circulating endothelial progenitor cells, and von Willebrand factor in pregnancies complicated by hypertensive disorders. in American journal of reproductive immunology (New York, N.Y. : 1989) 2017
PP2B (显示 CAN ELISA试剂盒)-Aalpha-Munc18c complex supports agonist-induced VWF secretion by HUVECs.
Deficiency of the von Willebrand factor-cleaving protease ADAMTS13 (显示 ADAMTS13 ELISA试剂盒) is central to the pathophysiology of thrombotic thrombocytopenic purpura. Reviewed is the evidence emerged from epidemiological studies of an inverse relationship between the plasma levels of ADAMTS13 (显示 ADAMTS13 ELISA试剂盒) and the risk of acute coronary syndrome. [review]
genetic variation of vWF V1565L polymorphism modulates ADAMTS13 (显示 ADAMTS13 ELISA试剂盒) activity.
Plasma levels of VWF antigen and activity are significantly increased with concomitant reduction in plasma ADAMTS13 (显示 ADAMTS13 ELISA试剂盒) activity in patients with subarachnoid haemorrhage.
Report a diagnostic algorithm that can reliably identify pathogenic variants of factor 8/9 and von Willebrand factor and diagnose patients with hemophilia A, hemophilia B or von Willebrand disease.
analysis of an artificial botrocetin that can inhibit the VWF-GPIb interaction
VWF binding to MMRN1 (显示 MMRN1 ELISA试剂盒) was enhanced by shear exposure and ristocetin, and required VWF A1A2A3 region, specifically the A1 and A3 domains.
coronary thrombi in STEMI patients resistant to fibrinolysis are characterised by higher fibrin, P-selectin (显示 SELP ELISA试剂盒) and VWF content than lysis-sensitive thrombi
We compared the classical Sanger sequencing approach and NGS to assess the value-added effect on the analysis of the mutation distribution in different types of VWD. Sixty-two different VWF mutations were identified, 27 of which had not been previously described. NGS detected 26 additional mutations, contributing to a broad overview of the mutant alleles present in each VWD type.
These observations support the hypothesis that a significantly reduced ADAMTS13 (显示 ADAMTS13 ELISA试剂盒)/VWF ratio in the coronary artery flow plays a pathogenic role in acute coronary syndromes (ACS) and suggest that transition from laminar to turbulent flow at sites of coronary stenosis further enhances VWF activation and deposition.
In conclusion, endothelial vWF knockdown prevented angiotensin II-induced ET-1 (显示 EDN1 ELISA试剂盒) upregulation through attenuation of NOX-mediated O2- production.
alterations in glycosylation of vWF and other adhesion proteins associated with the targeting of the alpha1,3-Gal (显示 GAL ELISA试剂盒)-epitope in mutant swine may have salutatory effects on the primate platelet activation observed in these xenografts.
Hemodynamic activation of vWF and increased plasma ADAMTS-13 (显示 ADAMTS13 ELISA试剂盒) may have contributed to reduced high-molecular-weight vWF multimers and impairment of the vWF-platelet aggregation pathway during mechanical circulatory support.
both the gpIb-VWF interaction and the integrin alpha(2 (显示 ITGA2 ELISA试剂盒))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (显示 GSTA3 ELISA试剂盒))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF is bound
The low-molecular-weight heparin (LMWH) Tinzaparin inhibited Von Willebrand factor (VWF) fiber formation and vessel occlusion in tumor vessels by blocking thrombin (显示 F2 ELISA试剂盒)-induced endothelial cells (ECs) activation and vascular endothelial growth factor-A (VEGF-A (显示 VEGFA ELISA试剂盒))-mediated VWF release.
In a laser injury-induced thrombosis model, P-selectin (显示 SELP ELISA试剂盒) modulates thrombus propagation independently of VWF and TSP1 (显示 GZMA ELISA试剂盒)
Refrigeration-induced binding of VWF to platelets facilitates their rapid clearance by inducing GPIbalpha (显示 GP1BA ELISA试剂盒)-mediated signaling.
BLOC-2 (显示 HPS6 ELISA试剂盒) subunit HPS6 (显示 HPS6 ELISA试剂盒) deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells
A novel single-domain antibody against von Willebrand factor A1 domain that interferes with VWF-platelet interactions in vivo. By using this sdAb, show that the A1 domain is pertinent to the participation of VWF in the inflammatory response.
These experiments delineate an unexpected pathway in which microbiota-triggered TLR2 signaling alters the synthesis of proadhesive VWF by the liver endothelium and favors platelet integrin-dependent thrombus growth.
ADAMTS13 (显示 ADAMTS13 ELISA试剂盒) controls vascular remodeling by modifying VWF reactivity during stroke recovery.
these novel findings support the hypothesis that conformation of the VWF A domains plays a critical role in modulating macrophage-mediated clearance of VWF in vivo.
results revealed localized vascular expression of FVIII (显示 F8 ELISA试剂盒) and von Willebrand factor and identified lymphatic endothelial cell as a major cellular source of FVIII (显示 F8 ELISA试剂盒) in extrahepatic tissues.
Endothelial cell derivedVWF is the major determinant that mediates VWF-dependent ischemic stroke by promoting postischemic thrombo-inflammation.
The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.
von Willebrand factor
, coagulation factor VIII VWF