USP8 ELISA试剂盒

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation.

产品数据
  • 3
类型
  • 4
    Kit
抗原
  • 4
适用
  • 4
应用范围
  • 4
实验类型
  • 4
Analytical Method
  • 4
检测方法
  • 4
Plate
  • 4
样本
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4 产品
Pre-coated, 样品类型: Plasma, Serum
适用
检测方法Colorimetric, Sandwich ELISA
检测范围0.313-20 ng/mL
订购详情 分类号码 ABIN1117711
$630.00
96 tests
加上运输费 $45.00
12至14个工作日
Pre-coated, 样品类型: Cell Lysate, Tissue Homogenate
适用
检测方法Colorimetric, Sandwich ELISA
检测范围0.31 ng/mL - 20 ng/mL
订购详情 分类号码 ABIN420762
$736.84
加上运输费 $45.00
13至16个工作日
Pre-coated, 样品类型: Cell Lysate, Tissue Homogenate
适用
检测方法Colorimetric, Sandwich ELISA
检测范围0.312 ng/mL - 20 ng/mL
订购详情 分类号码 ABIN1573011
$908.41
加上运输费 $45.00
15至17个工作日
Pre-coated, 样品类型: Cell Lysate, Tissue Homogenate
适用
检测方法Colorimetric, Sandwich ELISA
检测范围0.312 ng/mL - 20 ng/mL
订购详情 分类号码 ABIN5659745
$971.15
96 tests
加上运输费 $45.00
8至12个工作日
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USP8 抗原简介

蛋白简介

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.

Gene names and symbols associated with USP8

  • ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109) 抗体
  • ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369) 抗体
  • ubiquitin specific peptidase 8 (USP8) 抗体
  • ubiquitin specific peptidase 8 (Usp8) 抗体
  • AI574262 抗体
  • AW557536 抗体
  • HumORF8 抗体
  • mKIAA0055 抗体
  • Ubpy 抗体

Protein level used designations for USP8

ubiquitin carboxyl-terminal hydrolase 8 , ubiquitin-specific-processing protease 8 , ubiquitin specific peptidase 8 , ubiquitin carboxyl-terminal hydrolase 8-like , deubiquitinating enzyme 8 , hUBPy , ubiquitin isopeptidase Y , ubiquitin specific protease 8 , ubiquitin thioesterase 8 , ubiquitin thiolesterase 8 , putative deubiquitinating enzyme

GENE ID SPECIES
9310109 Arabidopsis lyrata subsp. lyrata
10031598 Arthroderma gypseum CBS 118893
100408559 Callithrix jacchus
100437819 Pongo abelii
9101 Homo sapiens
296121 Rattus norvegicus
84092 Mus musculus
100157546 Sus scrofa
415451 Gallus gallus
100351436 Oryctolagus cuniculus
100720255 Cavia porcellus