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Translocase of Inner Mitochondrial Membrane 50 Homolog (S. Cerevisiae) (TIMM50) ELISA试剂盒

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (By similarity). 再加上，我们可以发Translocase of Inner Mitochondrial Membrane 50 Homolog (S. Cerevisiae) 抗体 (47) 和 Translocase of Inner Mitochondrial Membrane 50 Homolog (S. Cerevisiae) 蛋白 (5)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
TIMM50 66525 Q9D880
TIMM50 92609 Q3ZCQ8
TIMM50    
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适于 Translocase of Inner Mitochondrial Membrane 50 Homolog (S. Cerevisiae) 相互作用对的更多 ELISA 试剂盒

Arabidopsis thaliana Translocase of Inner Mitochondrial Membrane 50 Homolog (S. Cerevisiae) (TIMM50) interaction partners

  1. A knockout mutant of the Arabidopsis TIM50 gene showed a reduction in hypocotyl length. TIM50 knockout caused enlargement and deformation of the mitochondrial structure and a reduction in intracellular ATP levels.

Mouse (Murine) Translocase of Inner Mitochondrial Membrane 50 Homolog (S. Cerevisiae) (TIMM50) interaction partners

  1. TIM50 deficiency increased heart and cardiomyocyte size with more severe cardiac fibrosis compared with wild-type littermates. In cardiomyocyte-specific TIM50 transgenic mice, the hypertrophic and fibrotic phenotypes were all alleviated.

Human Translocase of Inner Mitochondrial Membrane 50 Homolog (S. Cerevisiae) (TIMM50) interaction partners

  1. Amino acid changes that suppress the association of Tim50 with Cytochrome P450 side-chain cleavage enzyme ablate metabolic activity.

  2. High TIMM50 expression is associated with non-small cell lung cancer progression.

  3. These results indicate that mutations in TIMM50 cause multiple mitochondrial bioenergetic dysfunction and that functional TIMM50 is essential for cell survival in OxPhos-dependent conditions.

  4. Expression of TIM50 was downregulated in hypertrophic hearts.

  5. Missense mutations in TIMM50 are likely manifesting by severe intellectual disability and epilepsy accompanied by 3-methylglutaconic aciduria and variable mitochondrial complex V deficiency.

  6. TIM50 has a role in regulating cell proliferation and apoptosis through decreasing mitochondrial membrane potential in breast cancer cell

  7. the interaction of divalent metal ions with the intermembrane space domain of Tim50 (Tim50(IMS)) and the interaction of presequence peptides with Tim50(IMS) in presence of Ca(2+) ion was investigated.

  8. The far-UV CD spectra of Tim50(IMS) in native and denatured states revealed that the protein has a significantly folded secondary structure consisted of alpha-helixes and beta-sheets.

  9. Tim50 regulates 3betaHSD2 expression and activity, representing a new role for translocases in steroidogenesis.

  10. TIM50, was upregulated in a non-small cell lung carcinoma cell line (H1299) that expressed the p53 mutants R175H and R273H compared to cells lacking p53.

  11. Tim50 is important for both mitochondrial function and early neuronal development

  12. Tim50a, a nuclear isoform of the mitochondrial Tim50, interacts with coilin, snRNPs, and SMN

Translocase of Inner Mitochondrial Membrane 50 Homolog (S. Cerevisiae) (TIMM50) 抗原简介

Antigen Summary

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (By similarity).

Gene names and symbols associated with TIMM50

  • Haloacid dehalogenase-like hydrolase (HAD) superfamily protein (TIM50) 抗体
  • protein translocase subunit (TIM50) 抗体
  • translocase of inner mitochondrial membrane 50 (Timm50) 抗体
  • translocase of inner mitochondrial membrane 50 (TIMM50) 抗体
  • 2810403L02Rik 抗体
  • AU015082 抗体
  • emb1860 抗体
  • embryo defective 1860 抗体
  • F14J16.15 抗体
  • F14J16_15 抗体
  • TIM50 抗体
  • TIM50L 抗体

Protein level used designations for TIMM50

potential mitochondrial presequence translocase guide protein , mitochondrial import inner membrane translocase subunit TIM50 , translocase of inner mitochondrial membrane 50 homolog , Tim50-like protein , homolog of yeast Tim50

GENE ID SPECIES
842040 Arabidopsis thaliana
3644530 Candida albicans SC5314
66525 Mus musculus
92609 Homo sapiens
476461 Canis lupus familiaris
505489 Bos taurus
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