Thyrotrophic Embryonic Factor 蛋白 (TEF)

TEF encodes a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. 再加上,我们可以发TEF 抗体 (46)TEF 试剂盒 (28)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
TEF 21685 Q9JLC6
TEF 7008 Q10587
TEF 29362 P41224
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
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大肠杆菌(E. Coli) His tag 0.5 mg Log in to see 13至16个工作日
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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酵母菌 Phodopus sungorus His tag   1 mg Log in to see 60至71个工作日
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酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
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酵母菌 小鸡 His tag   1 mg Log in to see 60至71个工作日
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TEF 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Human , ,
,
Rat (Rattus)

更多Thyrotrophic Embryonic Factor (TEF)互动伙伴

Zebrafish Thyrotrophic Embryonic Factor (TEF) interaction partners

  1. TEF regulates light-induced transcription of DNA repair genes.

Mouse (Murine) Thyrotrophic Embryonic Factor (TEF) interaction partners

  1. In Ccdc80(-/-) mice, expression of the core clock member Arntl/Bmal1 (显示 ARNTL 蛋白) was reduced whereas that of the oscillating transcription factors Dbp (显示 GC 蛋白) and Tef was increased in all tissues examined.

  2. evidence of TEF regulation through a miR (显示 MLXIP 蛋白)-125b-mediated pathway

  3. Data show that S100a9 (显示 S100A9 蛋白), Mmp10 (显示 MMP10 蛋白) and Ang2 (显示 ANGPT2 蛋白) were among the most downregulated genes, whereas Per3, Tef and Prdx6 (显示 PRDX6 蛋白) were significantly upregulated in the DMH (显示 DST 蛋白) + Calcium group.

  4. we demonstrate that D site albumin promoter binding protein/thyrotroph embryonic factor/hepatic leukemia factor (显示 HLF 蛋白) triple knockout mice develop cardiac hypertrophy and left ventricular dysfunction associated with a low blood pressure

  5. TEF contributes to the activation of the telokin (显示 MYLK 蛋白) promoter in smooth muscle cells in a calcium-dependent manner

  6. mice deficient for all three PAR (显示 AFG3L2 蛋白) bZip proteins (DBP (显示 GC 蛋白),HLF (显示 HLF 蛋白),& TEF) are highly susceptible to generalized spontaneous and audiogenic epilepsies, frequently lethal. Pyridoxal kinase (显示 PDXK 蛋白) is a target gene of PAR (显示 AFG3L2 蛋白) bZip proteins in both liver and brain

  7. The Tef protein control the expression of many enzymes and regulators involved in detoxification and drug metabolism, such as cytochrome P450 enzymes, carboxylesterases, and constitutive androstane receptor (显示 NR1I3 蛋白) (CAR).

  8. Data show that the clock knockout mice or mice devoid of dbp (显示 GC 蛋白)/hlf (显示 HLF 蛋白)/tef (triple knockout) exhibit significant changes in renal expression of several key regulators of water or sodium balance.

Human Thyrotrophic Embryonic Factor (TEF) interaction partners

  1. Resequencing three candidate genes (HOMER1 (显示 HOMER1 蛋白), SLC6A4 (显示 SLC6A4 蛋白), and TEF) discovers seven potentially deleterious variants susceptibility to major depressive disorder and suicide attempts in Chinese.

  2. findings show the polymorphisms of Cry1 (显示 CRY1 蛋白) rs2287161 and Tef rs738499 are associated to major depressive disorder in the Chinese population

  3. The polymorphism of Tef rs738499 is associated with depression symptoms in parkinson disease.

  4. the TT genotype in Tef rs738499 is associated with sleep disturbances in Parkinson disease.

  5. evidence of TEF regulation through a miR (显示 MLXIP 蛋白)-125b-mediated pathway

  6. TEF-expressing cells accumulated in G(0)/G(1) phase without undergoing apoptosis.

蛋白简介TEF

蛋白简介

This gene encodes a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP)\; VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TEF

  • thyrotrophic embryonic factor a (tefa)
  • thyrotrophic embryonic factor (tef)
  • TEF, PAR bZIP transcription factor (TEF)
  • thyrotroph embryonic factor (Tef)
  • TEF, PAR bZIP transcription factor (Tef)
  • 2310028D20Rik 蛋白
  • DKFZp459A027 蛋白
  • TEF 蛋白
  • tefb 蛋白
  • tefbeta 蛋白
  • VBP 蛋白
  • wu:fa12f02 蛋白
  • wu:fb11h02 蛋白
  • xtef 蛋白
  • zTEF[a] 蛋白

Protein level used designations for TEF

thyrotroph embryonic factor beta , thyrotrophic embryonic factor , thyrotroph embryonic factor , thyrotroph embryonic factor homolog , transcription factor VBP , vitellogenin binding protein (VBP), beta/beta isoform , vitellogenin gene-binding protein

GENE ID SPECIES
30674 Danio rerio
550073 Xenopus (Silurana) tropicalis
100173555 Pongo abelii
21685 Mus musculus
7008 Homo sapiens
607883 Canis lupus familiaris
29362 Rattus norvegicus
396342 Gallus gallus
616076 Bos taurus
100192430 Ovis aries
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