Tetraspanin 8 (TSPAN8) ELISA试剂盒

The protein encoded by TSPAN8 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. 再加上,我们可以发Tetraspanin 8 抗体 (81)Tetraspanin 8 蛋白 (7)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
TSPAN8 7103 P19075
小鼠 TSPAN8 TSPAN8 216350 Q8R3G9
大鼠 TSPAN8 TSPAN8 171048  
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Xenopus laevis Tetraspanin 8 (TSPAN8) interaction partners

  1. overexpression of tm4sf3 promoted development of annular pancreas.

Human Tetraspanin 8 (TSPAN8) interaction partners

  1. TSPAN8 mediated Wnt/beta-catenin pathway through binding to NOTCH2. The role of TSPAN8 in the drug resistance of gastric cancer.

  2. these data point to a crucial role of Co-029 in the modulation of colon cancer cell motility which could be related to the protumoral effect reported for this tetraspanin. Among surface molecules able to mediate Co-029 function, E-cadherin, EGFR and CD44 appear as likely candidates.

  3. Single nucleotide polymorphism in TSPAN8 gene is associated with pathogenesis of bipolar disorder.

  4. Tetraspanin-8 has a role in promoting hepatocellular carcinoma metastasis by increasing ADAM12m expression

  5. LCMR1 modulation was sufficient to positively regulate endogenous Tspan8 expression, with concomitant in vitro phenotypic changes such as loss of melanoma cell-matrix adherence and increase in invasion, and Tspan8 expression promoted tumourigenicity in vivo.

  6. Data indicate a regulatory role for tetraspanin 8 (Tspan8) in melanoma progression by modulating cell-matrix interactions through beta1 integrin - integrin-linked kinase (ILK) axis and establish Tspan8 as a negative regulator of ILK activity.

  7. TSPAN8 might be important for the orchestration of meprin beta at the cell surface with impact on certain proteolytic processes

  8. Knocking down TSPAN8 in AEG-1-overexpressing human hepatocellular carcinoma (HCC) cells markedly inhibited invasion and migration without affecting proliferation. TSPAN8 knockdown profoundly abrogated AEG-1-induced primary tumor and intrahepatic metastasis in an orthopic xenograft model in athymic nude mice

  9. Knockdown and knockout models revealed that CD151 and Tspan8 act as molecular facilitators in wound healing, angiogenesis and tumor progression. [review]

  10. Results provide evidence that TSPAN8 may contribute to the pathogenesis of lung cancer by promoting cell viability and proliferation.

  11. TSPAN8 is involved in tumor progression and is an independent prognostic classifier in patients with gastric cancer.

  12. This novel nuclear localization of TM4SF3 depends on androgen-induced nuclear localization of androgen receptor (AR) in both androgen-dependent and androgen-independent prostate cancer cell lines

  13. Our data suggest that TSPAN8-LEL may play an important role in mCRC cell invasion, and that the antibody we have developed could be a useful tool for inhibiting the invasion of TSPAN8-expressing mCRCs.

  14. Based on nasopharyngeal TSPAN8 gene expression in readily available Nasopharyngeal aspirate samples , we can discriminate between severity of disease in Respiratory syncytial virus infected infants.

  15. Tspn8 was over-expressed in multiple clinical malignant glioma tissues, and its expression level correlated with the grade of tumors.

  16. CO-029 functions as a regulator of both cell-matrix and cell-cell adhesion. During colon cancer progression, CO-029 promotes cancer cell movement by deregulating cell adhesions.

  17. PMA-induced Tspan8-internalization promotes cell migration, but reduces matrix and cell adhesion.

  18. High TSPAN8 is associated with melanoma invasiveness.

  19. claudin-7-associated EpCAM is recruited into (tetraspanin-enriched membrane microdomains) and forms a complex with CO-029 and CD44v6 that facilitates metastasis formation

  20. overexpression of TM4SF3 in esophageal cancer conferred advantage to the invasion and metastasis of this destructive disease

Tetraspanin 8 (TSPAN8) 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

Gene names and symbols associated with Tetraspanin 8 (TSPAN8) ELISA试剂盒

  • tetraspanin 8 L homeolog (tspan8.L) 抗体
  • tetraspanin-1 (LOC409511) 抗体
  • tetraspanin 8 (TSPAN8) 抗体
  • tetraspanin 8 (tspan8) 抗体
  • tetraspanin 8 (Tspan8) 抗体
  • C76990 抗体
  • CO-029 抗体
  • CO-29 抗体
  • E330007O21Rik 抗体
  • GB13255 抗体
  • MGC64550 抗体
  • tetraspanin-8 抗体
  • Tm4sf3 抗体
  • TSPAN-8 抗体
  • TSPAN8 抗体

Protein level used designations for Tetraspanin 8 (TSPAN8) ELISA试剂盒

tetraspanin 8 , transmembrane 4 superfamily member 3 , tetraspanin-8 , tspan-8 , tumor-associated antigen CO-029 , D6.1A

GENE ID SPECIES
380553 Xenopus laevis
409511 Apis mellifera
417854 Gallus gallus
496915 Xenopus (Silurana) tropicalis
718622 Macaca mulatta
743174 Pan troglodytes
474448 Canis lupus familiaris
7103 Homo sapiens
216350 Mus musculus
171048 Rattus norvegicus
617508 Bos taurus
100174494 Pongo abelii
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