anti-Tektin 4 (TEKT4) 抗体

Structural component of ciliary and flagellar microtubules. 再加上,我们可以发Tektin 4 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
TEKT4 7184 P14625
TEKT4 71840 Q149S1
TEKT4 302991 Q6AXV2
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antibodies-online.cn销售最多的anti-Tektin 4 抗体

Showing 10 out of 51 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-TEKT4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL 2至3个工作日
Cow 非结合性 WB WB Suggested Anti-TEKT4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate 100 μL 2至3个工作日
Cow 非结合性 WB 100 μL 11至14个工作日
非结合性 WB 100 μL 11至14个工作日
非结合性 WB Western blot analysis of TEKT4 Antibody in mouse spleen tissue lysates (35ug/lane) 400 μL 2至3个工作日
小鼠 非结合性 WB Western Blot analysis of TEKT4 expression in transfected 293T cell line by TEKT4 MaxPab polyclonal antibody.Lane 1: TEKT4 transfected lysate(47.85 KDa).Lane 2: Non-transfected lysate. 50 μL 11至12个工作日
非结合性 ELISA, WB 100 μL 2至3个工作日
非结合性 WB Tektin 4 antibody used at 1 ug/ml to detect target protein. 50 μg 9至11个工作日
Alkaline Phosphatase (AP) ELISA, WB   200 μL 11至14个工作日
APC ELISA, WB   200 μL 11至14个工作日

更多抗Tektin 4的相互作用对抗体

Human Tektin 4 (TEKT4) interaction partners

  1. Computational docking analysis demonstrates that GRP94 preferentially interacts with ADAM12S over ADAM12L. Both the protein expression level and the secretion of ADAM12S are regulated by GRP94 expression and knockdown. A link between these two proteins is highly expressed in cancer cells. Furthermore, our studies define a new ADAM12S-specific regulator that may contribute to cancer development.

  2. Elevated expression of HSP90alpha and HSP90beta was found to correlate with poor prognosis of head and neck cancers cases. Thus, elevated levels HSP90alpha and HSP90beta in secreted vesicles are potential prognostic biomarkers and therapeutic targets in metastatic oral squamous cell carcinoma.

  3. In this report, the authors show that HSP90 binding to HSF1 depends on HSP90 conformation and is only readily visualized for the ATP-dependent, N-domain dimerized chaperone, a conformation only rarely sampled by mammalian HSP90.

  4. data allowed us to determine that Gp96 binds to a complement C3 fragment encompassing amino acids 749-954, a functional complement C3 hot spot important for binding of different regulators

  5. GRP94 silencing modulates antineoplastic drug resistance of MG63 and 143B cells by inhibiting the induction of apoptosis.

  6. Among infants, an HSP90B1 gene-region variant is associated with BCG-induced IL-2 production and may be associated with protection from TB disease. HSP90B1 knockdown in human monocyte-like cell lines did not influence TLR2 surface localization nor Mtb replication. Together, these data suggest that HSP90B1 regulates T-cell, but not monocyte, responses to mycobacteria in humans.

  7. Our study revealed that TEKT4 shows important biological implications in papillary thyroid cancer

  8. we found that Hsp90beta was positively correlated with vasculogenic mimicry and epithelial-mesenchymal transformation-related proteins in hepatocellular carcinoma

  9. Glucose-regulated protein GRP94 contributes to the development of an aggressive phenotype in breast cancer cells.

  10. Concomitant high expression of ERalpha36, GRP78 and GRP94 is associated with aggressive papillary thyroid cancer behavior and may be used as a predictor for extrathyroid extension, lymph node metastasis, and distant metastasis.

  11. Overexpressed miR-150 attenuates hypoxia-induced human cardiomyocyte cell apoptosis by targeting GRP94.

  12. Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90beta as a molecular model for myotonia congenita has been described.

  13. Study demonstrated that the lack of gp96 in both the human monocytic cell line MM6 and in macrophages from LysMcre-gp96 floxed mice neither leads to a complete loss of TLR 2 expression nor to a complete loss of TLR-induced signaling, but is associated with an impaired phosphorylation of ERK and p38. These results reveal for the first time a crucial role for gp96 in the regulation of ERK and p38 kinases.

  14. HSP-gp96 promotes T cell response, enhances DC antigen presentation and induces cytokine secretion in human gastric cancer cell lines.

  15. our results besides adding further evidence in support of Grp94 as the shared tumor antigen in tumors of the GI tract, prove that it can be measured in plasma as valuable diagnostic marker of disease in the form of complexes with IgG that also exert immune-modulating activities on circulating immune cells.

  16. High GRP94 expression is associated with endometrioid adenocarcinoma.

  17. Immuno-stimulating peptide derived from HMGB1 is more effective than the N-terminal domain of Gp96 as an endogenous adjuvant for improvement of protein vaccines.

  18. These data demonstrate the essential role of the gp96-TLR interaction in priming T cell immunity and provide further molecular basis for the coupling of gp96-mediated innate with adaptive immunity.

  19. mutations in GRP94 that affect its IGF chaperone activity represent a novel causal genetic mechanism that limits IGF biosynthesis, quite a distinct mechanism from the known genes in the GH/IGF signaling network.

  20. In this instance, the ATP5B/CALR/HSP90B1/HSPB1/HSPD1-signaling network was revealed as the predominant target which was associated with the majority of the observed protein-protein interactions. As a result, the identified targets may be useful in explaining the anticancer mechanisms of ursolic acid and as potential targets for colorectal cancer therapy.

Mouse (Murine) Tektin 4 (TEKT4) interaction partners

  1. Data suggest that Tektin 4 is not associated with axonemal tubulins but instead associated with Outer Dense Fibers in rodent spermatozoa.

  2. TEKT4 is necessary for the proper coordinated beating of the sperm flagellum and male reproductive physiology

Cow (Bovine) Tektin 4 (TEKT4) interaction partners

  1. This study demonstrates that the expression patterns of tektin-4 were a proxy for an effect on spermatozoa motility and consequently bull infertility.

Tektin 4 (TEKT4) 抗原简介


This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.

Gene names and symbols associated with anti-Tektin 4 (TEKT4) 抗体

  • heat shock protein 90 beta family member 1 (HSP90B1) 抗体
  • tektin 4 (Tekt4) 抗体
  • tektin 4 (TEKT4) 抗体
  • tektin-4 (LOC490081) 抗体
  • tektin 4 S homeolog (tekt4.S) 抗体
  • tektin 4 (tekt4) 抗体
  • tektin-4 (LOC100719827) 抗体
  • tektin-4 (LOC110259951) 抗体
  • 1700010L19Rik 抗体
  • ECGP 抗体
  • GP96 抗体
  • GRP94 抗体
  • RGD1308075 抗体
  • Tek4 抗体
  • Tekt4 抗体
  • Tektin4 抗体
  • TRA1 抗体

Protein level used designations for anti-Tektin 4 (TEKT4) 抗体

94 kDa glucose-regulated protein , endoplasmin , endothelial cell (HBMEC) glycoprotein , heat shock protein 90 kDa beta member 1 , stress-inducible tumor rejection antigen gp96 , tumor rejection antigen (gp96) 1 , tumor rejection antigen 1 , tektin-4 , testicular microtubules-related protein 4 , tektin 4

7184 Homo sapiens
71840 Mus musculus
150483 Homo sapiens
302991 Rattus norvegicus
416527 Gallus gallus
459397 Pan troglodytes
490081 Canis lupus familiaris
496070 Xenopus laevis
510343 Bos taurus
559407 Danio rerio
708925 Macaca mulatta
100145069 Xenopus (Silurana) tropicalis
100598078 Nomascus leucogenys
100719827 Cavia porcellus
110259951 Sus scrofa
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