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TAS2R16 encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. 再加上，我们可以发TAS2R16 蛋白 (4)和数多这个蛋白质的别的产品。
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We did not find any statistically significant association between risk of developing sporadic colorectal cancer and selected single nucleotide polymorphisms. However, after stratification by histology (colon vs. rectum) we found that rs1525489 was associated with increased risk of rectal cancer with a (Ptrend of = 0.0071).
genetic association studies in populations in Northern Europe, Maghreb, and Sri Lanka: Data suggest that SNPs in TAS2R50 (rs1376251), TRPM5 (rs800345), and TAS2R16 (rs860170) are associated with cultural food preferences; TAS2R16 (rs860170) strongly differentiates populations and is associated to salicin bitterness perception. (TRPM5 = transient receptor potential cation channel subfamily M member 5)
Principal component analysis of binding energies for single-point mutants of hT2R16 bound to an agonist correlate with experimental mutant cell response.
No significant association between rs702424 alleles and salicin bitter taste recognition, implying that this site does not contribute to salicin phenotypic variance.
Results showed that individuals with at least one derived T-allele at polymorphic site 516 have a higher sensitivity to salicin bitterness compared with individuals homozygous for the ancestral G-allele.
Bitter taste receptor polymorphisms in TAS2R16 may be associated with human aging
The authors discuss the association between the TAS2R16 gene and the evolution of bitter taste receptors in different populations.
TAS2R16 is responsible for the bitterness of gentiobiose.
molecular interaction between hTAS2R16 and beta-D-glucopyranoside
TAS2R16 is present in taste receptor cells on the tongue and is activated by bitter beta-glucopyranosides, and mediates bitter taste
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence, especially in African-Americans.
Functional variants in both TAS2R16 and TAS2R38 correlate with alcohol consumption in African-American families.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception.
taste receptor type 2 member 16
, taste receptor T2R16
, bitter taste receptor Bota-T2R16
, candidate taste receptor mt2r40
, taste receptor, type 2, member 16
, candidate taste receptor T2R16