anti-Taste Receptor, Type 1, Member 2 (TAS1R2) 抗体

Putative taste receptor. 再加上,我们可以发Taste Receptor, Type 1, Member 2 试剂盒 (7)Taste Receptor, Type 1, Member 2 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
TAS1R2 80834 Q8TE23
TAS1R2 100270683 Q9Z0R7
TAS1R2 83770 Q925I4
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Showing 10 out of 80 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-TAS1R2 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain 100 μL 2至3个工作日
$319.00
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山羊 非结合性 ELISA, WB ABIN238627 (0.3 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg 6至7个工作日
$429.84
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非结合性 EIA, WB TAS1R2 Antibody (C-term) western blot analysis in K562 cell line lysates (35µg/lane).This demonstrates the TAS1R2 antibody detected the TAS1R2 protein (arrow). 0.4 mL 6至8个工作日
$484.00
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非结合性 IHC, IHC (p) Anti-TAS1R2 antibody  ABIN1049397 IHC staining of human taste receptor cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-TAS1R2 / T1R2 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11至14个工作日
$484.00
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山羊 非结合性 ELISA, WB 100 μg 11至14个工作日
$610.50
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非结合性 ELISA, WB Western blot analysis of TAS1R2 using HUVEC whole cell lysates Western blot analysis of extracts from HUVEC, using TAS1R2 Antibody. The lane on the left was treated with blocking peptide. 100 μL 11至12个工作日
$390.77
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山羊 非结合性 WB   0.1 mg 4至8个工作日
$462.00
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非结合性 WB Western blot analysis in K562 cell line lysates (35ug/lane). 400 μL 2至3个工作日
$515.63
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非结合性 ICC, IF   100 μL 3至4个工作日
$466.18
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非结合性 ELISA   100 μL 11至14个工作日
$537.17
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引用最多的anti-Taste Receptor, Type 1, Member 2 抗体

  1. Human Polyclonal TAS1R2 Primary Antibody for ELISA, WB - ABIN548058 : Jang, Kokrashvili, Theodorakis, Carlson, Kim, Zhou, Kim, Xu, Chan, Juhaszova, Bernier, Mosinger, Margolskee, Egan: Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

更多抗Taste Receptor, Type 1, Member 2的相互作用对抗体

Human Taste Receptor, Type 1, Member 2 (TAS1R2) interaction partners

  1. The data further reveal that the C terminus of the extracellular cysteine-rich domain needs to be properly folded for T1R3 dimerization and co-trafficking, but not for surface expression of T1R2 alone. These results guided the modeling of the T1R2-T1R3 dimer in living cells.

  2. genetic association studies in population of preschool-aged children in Guelph, Ontario: Data suggest that SNPs in CD36 (rs1761667), TAS1R2 (rs35874116), and TAS2R38 (rs713598) are associated with snacking behavior in the population studied. [PILOT PROJECTS]

  3. We observe that binding of agonists to VFD2 of TAS1R2 leads to major conformational changes to form a TM6/TM6 interface between TMDs of TAS1R2 and TAS1R3, which is consistent with the activation process observed biophysically on the metabotropic glutamate receptor 2 homodimer.

  4. Alleles from each TAS1R2 locus (GG compared with AA alleles of rs12033832, and CT/CC compared with TT alleles of rs35874116) were related to higher consumption of carbohydrates (% energy) and higher amount of sweet foods, respectively (P<0.05).

  5. The molecular anatomy of sweet taste receptor dimers T1R2-T1R3 has been presented.

  6. no significant associations between GLUT2 and/or TAS1R2 polymorphisms and fillings were found, but allele frequencies of the TAS1R2 variant were marginally significantly different between children with DMFT = 0 and DMFT >/=1. no significant interaction between both genes and risk of dental caries was found. GLUT2 and TASR1 polymorphisms may influence the risk of caries in the Czech population

  7. In conclusion, the Val/Val genotype of TAS1R2 was associated with a higher carbohydrate intake and HTG.

  8. high-risk caries experience (>8 caries) was found to be associated with TAS1R2 rs35874116 homozygous polymorphic genotype.

  9. The rs12033832 single nucleotide polymorphism in TAS1R2 is associated with sucrose taste and sugar intake, but the effect differs depending on BMI

  10. human and mouse membrane trafficking systems for sweet taste receptors T1r2 and T1r3

  11. effects of artificial sweeteners on adipose tissue may be largely independent of the classical sweet taste receptors, T1R2 and T1R3

  12. Interaction between brazzein and the amino terminal domain of the sweet receptor subunit T1R2 showed a stronger interaction at 7 degrees C than at 37 degrees C.; the low temperature conformation, alters the orientations of 2 loops known to be critical for the sweetness of brazzein, may represent the bound state of brazzei in the complex with the human sweet receptor.

  13. associated with caries risk

  14. Genetic ablation of the sweet TR protein T1R2 obliterates fructose-induced insulin release and its potentiating effects on glucose-stimulated insulin secretion in vitro and in vivo.

  15. T1R2/T1R3 is involved in glucose-dependent secretion of satiation peptides

  16. Our findings show that a genetic variation in TAS1R2 affects habitual consumption of sugars and may contribute to interindividual differences in changing behaviors in response to dietary counseling.

  17. significant associations were seen in TAS1R2 for caries risk and/or protection.

  18. Data show that Positive allosteric modulators of the sweet taste receptor could help reduce the caloric content in food and beverages while maintaining the desired taste.

  19. Results from mutagenesis and chimeras of the receptor indicated that brazzein interacts with both T1R2 and T1R3 and that the Venus flytrap module of T1R2 is important for brazzein agonism.

  20. Interactions between the human sweet-sensing T1R2-T1R3 receptor and sweeteners detected by saturation transfer difference NMR spectroscopy.

Mouse (Murine) Taste Receptor, Type 1, Member 2 (TAS1R2) interaction partners

  1. Using T1R2-knock out (KO) mice authors evaluated the role of STRs in the regulation of glucose absorption in vivo and in intact intestinal preparations ex vivo.

  2. our platform provides in depth analysis of new sweeteners either alone or in competition and/or inhibition studies to fully understand the structure/functional role of ATD region of T1R2 that transpires in the initial binding event prior to sweet taste response.

  3. Data suggest that Tas1r2 and Tas1r3 are involved in regulation of Glp1 secretion in enteroendocrine cells; 3DG (3-deoxyglucosone) attenuates high glucose-stimulated Glp1 secretion by antagonizing Tas1r2/Tas1r3 subunits and downstream cAMP signaling. (Tas1r2 = sweet taste receptor subunit Tas1r2; Tas1r3 = sweet taste receptor subunit Tas1r3; Glp1 = glucagon-like peptide-1)

  4. Data, including data from studies with mutant and knockout mice, suggest that Tas1R3 and Tas1R2 are expressed endogenously in osteoclast stem cells; their expression levels parallel robust increase in osteoclast biomarker Ctsk during osteoclast differentiation. (Ctsk = cathepsin K)

  5. mice lacking T1R2 + T1R3 and controls were tested in a taste discrimination task to determine whether maltodextrins are 1) detectable when both receptor subunits are absent and 2) perceptually distinct from that of sucrose. Some KO mice were only sensitive to the higher Polycose concentrations, implicating potential allelic variation in the putative polysaccharide receptor pathways unmasked by the absence of T1R2+T1R3.

  6. results implicate each subunit of the T1R2+T1R3 dimer in the behavioral response to P-containing taste compounds

  7. T1R2 plays an important role in glucose homeostasis during diet-induced obesity through the regulation of yet to be identified molecular mechanisms that alter energy disposal and utilization in peripheral tissues. T1r2 was upregulated in the adipose tissue of wild type mice in response to high fat/low carbohydrate diet, and their expression positively correlated with fat mass and glucose intolerance.

  8. Mice possess two taste transduction pathways for sugars. One mediates behavioral attraction to sugars and requires an intact T1r2+T1r3. The other mediates cephalic phase insulin release but does not require an intact T1r2+T1r3.

  9. human and mouse membrane trafficking systems for sweet taste receptors T1r2 and T1r3

  10. T1R2 and T1R3 knockout mice have increased cortical bone mass and trabecular remodeling.

  11. effects of artificial sweeteners on adipose tissue may be largely independent of the classical sweet taste receptors, T1R2 and T1R3

  12. T1R2+3 heterodimer is the principal receptor that mediates taste detection of natural sweeteners, but not of all carbohydrate stimuli.

  13. Genetic ablation of the sweet TR protein T1R2 obliterates fructose-induced insulin release and its potentiating effects on glucose-stimulated insulin secretion in vitro and in vivo.

  14. the present study provides behavioral evidence for the presence of a glucose polymer taste receptor that is independent of the T1R2+3 heterodimer.

  15. These results demonstrate the expression of bitter taste receptors of the T2R family in the mouse and rat gastrointestinal tract

  16. behavioral and physiological characterization of T1R1, T1R2, and T1R3 knockout mice

  17. analysis of heterodimeric models of the T1R2-T1R3 receptor

  18. In the present study, we compared the genomic organization of rodent T2R genes based on the recently completed mouse and rat genomes and examined tissue- and cell-specific expression of T2Rs.

  19. Each of the two subunits in the heteromeric T1R2:T1R3 sweet taste receptor binds sweet stimuli though with distinct affinities and conformational changes.

  20. T2Rs may regulate GI function via release of regulatory peptides and activation of the vagal reflex pathway.

Taste Receptor, Type 1, Member 2 (TAS1R2) 抗原简介

蛋白简介

Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners (By similarity).

Gene names and symbols associated with TAS1R2

  • taste 1 receptor member 2 (TAS1R2) 抗体
  • taste 1 receptor member 2 (Tas1r2) 抗体
  • taste receptor, type 1, member 2 (Tas1r2) 抗体
  • Aldh4a1 抗体
  • Gpr71 抗体
  • T1r2 抗体
  • Tr2 抗体

Protein level used designations for TAS1R2

taste receptor type 1 member 2 , G protein-coupled receptor 71 , G-protein coupled receptor 71 , sweet taste receptor T1R2 , aldehyde dehydrogenase 4 family, member A1 , taste receptor TR2 , candidate taste receptor T1R2

GENE ID SPECIES
529847 Bos taurus
80834 Homo sapiens
100270683 Rattus norvegicus
83770 Mus musculus
478213 Canis lupus familiaris
714666 Macaca mulatta
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