anti-TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) 抗体

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. 再加上,我们可以发TIFA 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
TIFA 92610 Q96CG3
小鼠 TIFA TIFA 211550 Q793I8
大鼠 TIFA TIFA 310877 Q5XIB9
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Showing 10 out of 29 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 EIA, WB Western blot analysis of TIFA Antibody (N-term) in CEM cell line lysates (35 µg/lane). TIFA (arrow) was detected using the purified Pab. 0.4 mL 6至8个工作日
$484.00
详细
非结合性 ELISA, WB   200 μL 11至16个工作日
$658.43
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APC ELISA, WB   200 μL 16 Days
$814.00
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HRP ELISA, WB   200 μL 16 Days
$814.00
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PE ELISA, WB   200 μL 16 Days
$814.00
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FITC ELISA, WB   200 μL 16 Days
$814.00
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Cy5.5 IF (p)   100 μL 14至21个工作日
$416.90
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HRP IHC (p), WB   100 μL 14至21个工作日
$416.90
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Alexa Fluor 555 IF (p)   100 μL 14至21个工作日
$416.90
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Alexa Fluor 647 IF (p)   100 μL 14至21个工作日
$416.90
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更多抗TIFA的相互作用对抗体

Human TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) interaction partners

  1. The results provide direct evidence and a structural basis for the TIFA-TRAF6 interaction, and show how this important biological function can be modulated.

  2. REVIEW: various mechanisms and pathways involved in H. pylori induction of NF-kappaB-dependent responses in gastric epithelial cells, including a 'state-of-the-art' review on the respective roles of NOD1 and ALPK1/TIFA pathways in these responses

  3. TIFA expression limited proliferation of multiple myeloma cancer cells. In conclusion these results indicate that TIFA functions as a key transducer in DNA damage-induced NF-kappaB activation

  4. TIFA may serve as a biomarker in the prediction of lung adenocarcinoma. Furthermore, TIFA may modulate lung cancer cell survival and proliferation through regulating the synthesis of apoptosis-associated proteins.

  5. TIFA is a crucial mediator in the endothelial innate immune response by potentiating and amplifying NLRP3 inflammasome via augmenting signals 1 and 2

  6. study revealed that host TIFA and H. pylori-derived heptose-1,7-bisphosphate are critical effectors of innate immune signaling that account for much of the inflammatory response to H. pylori in gastric epithelial cells

  7. These results define TIFA as a rheostat for intracellular bacterial replication, escalating the immune response to invasive Gram-negative bacteria that exploit the host cytosol for growth.

  8. we report that Aurora A is essential for phosphorylation of the TRAF-interacting protein TIFA

  9. This study reports the crystal structures of TIFA (residues 1-150, with the unstructured C-terminal tail truncated) and its complex with the N-terminal phosphothreonine9 peptide (residues 1-15).

  10. an innate immune signaling axis, mediated by phosphorylation-dependent oligomerization of the TRAF-interacting protein with forkhead-associated domain (TIFA) that is triggered by heptose-1,7-bisphosphate.

  11. identify a novel threonine phosphorylation site on TIFA and show that this phosphorylated threonine binds with the FHA domain of TIFA, leading to TIFA oligomerization and TIFA-mediated NF-kappaB activation

  12. TIFA induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism

Mouse (Murine) TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) interaction partners

  1. The increase in TIFA level appears to be a feed-forward mechanism involved in TLR4/MyD88-dependent signaling, leading to NF-kappaB activation and HMGB1 release

  2. TIFA is likely to mediate IRAK-1/TRAF6 interaction upon IL-1 stimulation

  3. We propose that ZCCHC11 is a unique TLR signal regulator, which interacts with TIFA after LPS treatment and suppresses the TRAF6-dependent activation of NF-kappaB.

TIFA 抗原简介

蛋白简介

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (By similarity).

Gene names and symbols associated with TIFA

  • TRAF interacting protein with forkhead associated domain (TIFA) 抗体
  • TRAF-interacting protein with forkhead-associated domain (tifa) 抗体
  • TRAF-interacting protein with forkhead-associated domain (Tifa) 抗体
  • TRAF-interacting protein with forkhead-associated domain S homeolog (tifa.S) 抗体
  • Ab2-389 抗体
  • T2bp 抗体
  • T6BP 抗体
  • TIFA 抗体
  • TIFAA 抗体
  • xtifa 抗体

Protein level used designations for TIFA

TRAF-interacting protein with forkhead-associated domain , TRAF-interacting protein with a forkhead-associated domain , TRAF-interacting protein with FHA domain-containing protein A , TRAF6-binding protein , TRAF2 binding protein , TRAF2-binding protein , TRAF6 binding protein , putative MAPK-activating protein PM14 , putative NF-kappa-B-activating protein 20 , Traf2 binding protein

GENE ID SPECIES
422692 Gallus gallus
471278 Pan troglodytes
487905 Canis lupus familiaris
100216213 Xenopus (Silurana) tropicalis
92610 Homo sapiens
211550 Mus musculus
310877 Rattus norvegicus
783855 Bos taurus
734184 Xenopus laevis
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