蛋白简介

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Gene names and symbols associated with TAPBP

• TAP binding protein (tapasin), tandem duplicate 1 (tapbp.1) 抗体
• TAP binding protein (tapbp) 抗体
• TAP binding protein (TAPBP) 抗体
• TAP binding protein (Tapbp) 抗体

• D17Wsu91e 抗体
• mhc1uda 抗体
• mhc1ufa 抗体
• NGS17 抗体
• SI:dZ179B20.1 抗体
• 显示所有的同义词和别名
• SI:dZ179B20.3 抗体
• SI:dZ179B20.7 抗体
• TAPA 抗体
• TAPBP 抗体
• TPN 抗体
• TPSN 抗体
• zgc:109814 抗体

Protein level used designations for TAPBP

tapasin , TAP binding protein , TAP-associated protein , TAP-binding protein , TPSN , NGS-17 , TPN