The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
Bengoechea, Pittman, Tuck, True, Weihl: "Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D." in: Human molecular genetics, Vol. 24, Issue 23, pp. 6588-602, (2015) (PubMed).
Aliases for SYNM 抗体
synemin (SYNM) 抗体 synemin, intermediate filament protein (synm) 抗体 synemin, intermediate filament protein (Synm) 抗体 synemin (Synm) 抗体 4930412K21Rik 抗体 AI852401 抗体 DMN 抗体 dmn 抗体 Dmn 抗体 E130104F11 抗体 si:dkey-25f3.3 抗体 SYN 抗体 Syn 抗体 Synemin 抗体