anti-Sulfiredoxin 1 (SRX1) 抗体

Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. 再加上,我们可以发Sulfiredoxin 1 试剂盒 (7)Sulfiredoxin 1 蛋白 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SRX1 140809 Q9BYN0
SRX1 296271  
SRX1 76650 Q9D975
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antibodies-online.cn销售最多的anti-Sulfiredoxin 1 抗体

Showing 10 out of 37 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Mouse brain lysates probed with Anti SRXN1 Polyclonal Antibody, Unconjugated  at 1:3000 for 90 min at 37˚C. 100 μL 3至7个工作日
$329.45
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山羊 非结合性 ELISA, WB   100 μg 6至7个工作日
$429.84
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山羊 非结合性 ELISA, WB 100 μg 11至14个工作日
$610.50
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非结合性 IHC, WB Western blot analysis of extracts of A549 cells, using SRX1 antibody. ABIN6272872 at 1/100 staining Human lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11至12个工作日
$390.77
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山羊 非结合性 WB   0.1 mg 16 Days
$462.00
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山羊 非结合性 ELISA, WB SRXN1 polyclonal antibody  (0.5 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 11至12个工作日
$374.67
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HRP IHC (p)   100 μL 14至21个工作日
$428.45
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Cy5.5 IF (p)   100 μL 14至21个工作日
$428.45
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Cy7 IF (p)   100 μL 14至21个工作日
$428.45
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Cy3 IF (p)   100 μL 14至21个工作日
$428.45
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引用最多的anti-Sulfiredoxin 1 抗体

  1. Human Polyclonal SRX1 Primary Antibody for IF (p), IHC (p) - ABIN1387599 : Zhou, Zhou, Yu, Wu, Chen, Zhao et al.: Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ... in International journal of molecular medicine 2015 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SRX1 Primary Antibody for ELISA, WB - ABIN450073 : Jönsson, Johnson, Lowther: Structure of the sulphiredoxin-peroxiredoxin complex reveals an essential repair embrace. in Nature 2008 (PubMed)

更多抗Sulfiredoxin 1的相互作用对抗体

Human Sulfiredoxin 1 (SRX1) interaction partners

  1. Srx expression, MDA levels, and ROS levels in BGC823 cells were markedly inhibited upon treatment with diallyl trisulfide (DATS), a major constituent of garlic oil with proven anticancer effects. These results suggest that Srx may be an oxidative stress marker. Antioxidation may account for the anticancer potential of garlic.

  2. NRF2, DJ1 and SRNX1 are commonly expressed in diffusely infiltrating astrocytomas and they can be used in predicting patient prognosis.

  3. Study identify a role for Srxn1 as a denitrosylase for neuronal Prx2. Finding points to the NO/Srxn1 pair in a previously unrecognized redox cycle that modulates Prx2 peroxidase activity.

  4. Wnt/beta-catenin pathway was stimulated by sulfiredoxin in tumor cell line, with activation of CD44-its target genes-resulting in the promotion of invasion and migration in cervical cancer cell lines.

  5. This review will highlight the cumulative effects of sulfiredoxin in various systemic disorders with a strong emphasis on its target activity and the factors influencing its expression in such conditions.

  6. The up-regulated expression of Srx was significantly associated with lymph node metastasis, infiltration of vessels, and the depth of cancer invasion.

  7. The analysis of SXR polymorphism is a promising tool to predict both the favourable response to corticosteroids and the risk of developing steroid resistance

  8. rs6053666 of SRXN1 is associated with cerebrovascular disease in a Finnish cohort

  9. Increased expression of Srx protects peroxiredoxins against hyperoxidation in the early stage of hyperglycaemia.

  10. We silenced Srx by short hairpin RNA in HeLa and SiHa cells. Diminished Srx expression upregulated E-cadherin expression. The cell invasion and migration activity in the ShSrx group were obviously decreased in HeLa and SiHa cells.

  11. Study shows that Srx plays a critical oncogenic role to promote cell invasion and metastasis, which is at least partially due to its stimulation of the MAPK pathway through EGFR deacetylation.

  12. This review will summarize the molecular basis of differences in the affinity of Srx for individual Prx and the role of individual component of the Srx-Prx system in tumor progression and metastasis.

  13. Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-beta.

  14. NRF2 and SRXN1 genetic polymorphisms are associated with breast cancer risk and survival

  15. SRX forms a complex with S100A4 (and has stronger affinity for S-glutathionylated S100A4), regulates its activity, and mediates redox regulation of the interaction of S100A4 with nonmuscle myosin heavy chain II-A.

  16. Smokers and ex-smokers had significantly more sulfiredoxin expression in their tumors and in patients receiving cytostatic drugs or radiation therapy, sulfiredoxin expression predicted a poor prognosis.

  17. Srx functions as a novel component to maintain the balance between H2O2 production and elimination

  18. Real-time PCR validated that up-regulation of sulphiredoxin 1 homolog (SRXN1), hemeoxygenase 1 (HMOX1), and breast carcinoma amplified sequence 3 (BCAS3) were consistently modulated.

  19. Srx-Prx IV axis is critical for lung cancer maintenance and metastasis, suggesting that targeting the Srx-Prx IV axis may provide unique effective strategies for cancer prevention and treatment.

  20. sulfiredoxin 1 is associatd with the pathogenesis of human pulmonary fibrosis.

Mouse (Murine) Sulfiredoxin 1 (SRX1) interaction partners

  1. sulfiredoxin is degraded by Lon in a manner dependent on PrxIII hyperoxidation state.

  2. Srx is one of the critical components that contribute to mouse skin tumorigenesis in vivo.

  3. data provide in vivo evidence that loss of Srx renders mice resistant to azoxymethane/dextran sulfate sodium-induced colon carcinogenesis, suggesting that Srx has a critical oncogenic role in cancer development

  4. The concerted action of PrxIII and Srx is important for protection against pyrazole-induced oxidative stress arising from the convergent induction of CYP2E1-derived and ER stress-derived ROS in mitochondria.

  5. Srx functions as a novel component to maintain the balance between H2O2 production and elimination

  6. NO-mediated Srx up-regulation is mediated by the transcription factor nuclear factor erythroid 2-related factor (Nrf2) and the NO/Srx pathway inhibits generation of reactive oxygen species.

  7. Sulfiredoxin protects mice from lipopolysaccharide-induced endotoxic shock

  8. LPS-mediated Srx induction is dependent on both AP-1 and Nrf2, which is regulated by Nox2-derived reactive oxygen species.

  9. Synaptic activity upregulated the thioredoxin-peroxiredoxin reactivating gene sulfiredoxin.

Sulfiredoxin 1 (SRX1) 抗原简介

蛋白简介

Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.

Gene names and symbols associated with anti-Sulfiredoxin 1 (SRX1) 抗体

  • sulfiredoxin 1 (SRXN1) 抗体
  • sulfiredoxin 1 homolog (S. cerevisiae) (srxn1) 抗体
  • sulfiredoxin 1 (Srxn1) 抗体
  • sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1) 抗体
  • 1700127B04Rik 抗体
  • Ab2-390 抗体
  • AI854065 抗体
  • AW488194 抗体
  • C20orf139 抗体
  • Npn3 抗体
  • Srx 抗体
  • Srx1 抗体
  • TX01 抗体

Protein level used designations for anti-Sulfiredoxin 1 (SRX1) 抗体

sulfiredoxin 1 , sulfiredoxin 1 homolog , sulfiredoxin-1 , sulfiredoxin-1-like , sulfiredoxin 1 homolog (S. cerevisiae) , neoplastic progression 3 , neoplastic progression protein 3

GENE ID SPECIES
469853 Pan troglodytes
714997 Macaca mulatta
100331561 Danio rerio
140809 Homo sapiens
100858692 Gallus gallus
531606 Bos taurus
296271 Rattus norvegicus
76650 Mus musculus
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