Sphingosine-1-Phosphate Receptor 4 (S1PR4) ELISA试剂盒

S1PR4 is a member of the endothelial differentiation, G-protein-coupled EDG receptor gene family. 再加上,我们可以发S1PR4 抗体 (120)S1PR4 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
S1PR4 8698 O95977
S1PR4 13611 Q9Z0L1
大鼠 S1PR4 S1PR4 314649  
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产品编号 适用 灵敏度 范围 图像 规格 交付 价格 详细
小鼠 30 pg/mL 78.12 pg/mL - 5000 pg/mL   96 Tests 13至16个工作日
$757.89
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0.075 ng/mL 0.12 ng/mL - 8 ng/mL A typical standard curve 96 Tests 13至16个工作日
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Human Sphingosine-1-Phosphate Receptor 4 (S1PR4) interaction partners

  1. High S1PR4 expression is associated with anti-neutrophil cytoplasmic antibody-associated vasculitis.

  2. S1PR4 missense mutation is associated with variant blood cell traits.

  3. Shear stress did not induce rapid dephosphorylation of beta-arrestin-1 or rapid internalization of S1P3, indicating no GPCR activation. These findings suggest that Galphaq/11 participates in the sensing/transducing of shear stress independently of GPCR activation in ECs.

  4. Ig-like transcript 7 is rapidly internalized upon receptor-mediated endocytosis of TLR7/9 ligands to allow high IFN-alpha production. This is antagonized by S1PR4 signaling, thus decreasing TLR-induced IFN-alpha secretion.

  5. S1P2 translocation to the nucleus is regulated by an autocrine loop involving S1P and S1P4. In contrast, the translocation of Y416 phosphorylated c-Src to the nucleus appears to be regulated by a mechanism that does not involve S1P3 or S1P4.

  6. analysis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P-R) agonists

  7. findings highlight an important role for S1P(4) and SK1 in ER(-) breast cancer progression.

  8. Data show that S1P4 uses HER2 to regulate extracellular signal regulated kinase-1/2 MDA-MB-453 breast cancer cells.

  9. Data report that sphingosine 1-phosphate receptor 4 (S1P(4)) is specifically up-regulated during the development of human megakaryocytes from progenitor cells

  10. Mutation of the ligand selectivity residue from glutamic acid to glutamine confers lysophosphatidic acid sensitivity with preference for short-chain species

  11. FOXO1 controls the expression of L-selectin and EDG1 and EDG6, receptors that regulate lymphocyte trafficking

Mouse (Murine) Sphingosine-1-Phosphate Receptor 4 (S1PR4) interaction partners

  1. Genetic deletion of S1pr4 resulted in exacerbation of passive systemic anaphylaxis to IgE/anti-IgE.

  2. Data shows a reduced abundance of pDC, particularly CD4- pDC, in all organs of S1PR4-deficient vs. wildtype mice.

  3. analysis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P-R) agonists

  4. S1P4 signaling is involved in the regulation of dendritic cell function and TH17 T-cell differentiation. S1P4-mediated S1P signaling also modifies the course of various immune diseases in a murine model

  5. Megakaryocytes generated from S1P(4)-deficient murine bone marrow showed atypical and reduced formation of proplatelets in vitro.

  6. s1p(4) maps to mouse chromosome 10 and has similar tissue distribution to mouse Gna15; transcription of the two genes may be under control of the same enhancer elements

  7. binding pocket of mS1P4 (mouse S1P4) has recognition sites for the anionic phosphate and cationic ammonium groups that are equidistant from the end of the non-polar tail

  8. S1P4 mediates immunosuppressive effects of S1P by inhibiting proliferation and secretion of effector cytokines, while enhancing secretion of the suppressive cytokine IL-10

S1PR4 抗原简介

Antigen Summary

This gene is a member of the endothelial differentiation, G-protein-coupled EDG receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.

Gene names and symbols associated with S1PR4

  • sphingosine-1-phosphate receptor 4 (S1PR4) 抗体
  • sphingosine-1-phosphate receptor 4 S homeolog (s1pr4.S) 抗体
  • sphingosine-1-phosphate receptor 4 (S1pr4) 抗体
  • Edg6 抗体
  • Lpc1 抗体
  • S1p4 抗体
  • SLP4 抗体

Protein level used designations for S1PR4

endothelial differentiation, G protein coupled receptor 6 , endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6 , sphingosine 1-phosphate receptor 4 , sphingosine-1-phosphate receptor 4 , S1P receptor 4 , S1P receptor Edg-6 , endothelial differentiation G-protein coupled receptor 6 , endothelial differentiation, G-protein-coupled receptor 6 , sphingosine 1-phosphate receptor Edg-6 , S1p receptor 4 , endothelial differentiation G-protein-coupled receptor 6 , lysophospholipid receptor C1 , endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 6

GENE ID SPECIES
455581 Pan troglodytes
539534 Bos taurus
612082 Canis lupus familiaris
712637 Macaca mulatta
100380986 Xenopus laevis
8698 Homo sapiens
13611 Mus musculus
314649 Rattus norvegicus
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