Sphingosine-1-Phosphate Receptor 3 (S1PR3) ELISA试剂盒

S1PR3 encodes a member of the EDG family of receptors, which are G protein-coupled receptors. 再加上,我们可以发S1PR3 抗体 (142)S1PR3 蛋白 (10)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
S1PR3 1903 Q99500
S1PR3 13610 Q9Z0U9
S1PR3 306792  
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产品编号 适用 灵敏度 范围 图像 规格 交付 价格 详细
5.8 pg/mL 23.5-1500 pg/mL Typical standard curve 96 Tests 13至16个工作日
$910.56
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小鼠 29 pg/mL 78.12 pg/mL - 5000 pg/mL 96 Tests 13至16个工作日
$757.89
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大鼠 0.237 ng/mL 0.62 ng/mL - 40 ng/mL   96 Tests 13至16个工作日
$800.00
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Human Sphingosine-1-Phosphate Receptor 3 (S1PR3) interaction partners

  1. S1P induced the expression of some asthma-related genes, such as ADRB2, PTGER4, and CCL20, in bronchial epithelial cells. The knock-down of SIPR3 suppressed the expression of S1P-inducing CCL20.

  2. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases.

  3. Authors found that elevated levels of pSphK1 were positive correlation with high expression of S1P, which in turn promoted metastasis of TNBC through S1P/S1PR3/Notch signaling pathway.

  4. Sphingosine-1-phosphate receptor 3 (S1PR3) mediates multiple aspects of the inflammatory response during sepsis.

  5. in breast cancer cells overexpression of S1P3 and its activation by S1P has pro-inflammatory and pro-metastatic potential by inducing COX-2 expression and PGE2 signaling via EP2 and EP4.

  6. S1PR1/3 silencing alters proliferation, adhesion, viability and lateral motility in estrogen receptor-negative MCF-7 and estrogen receptor-positive MDA-MB-231 breast cancer cells.

  7. High S1PR3 expression is associated with increased lung adenocarcinoma.

  8. The S1P1,3 activation results in Akt phosphorylation and subsequent activation of eNOS via phosphorylation at serine(1177) and dephosphorylation at threonine(495).

  9. HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 and S1P3 receptors on vascular endothelium.

  10. The study shows that S1P receptor 3 (S1PR3) mRNA is overexpressed in EBV-positive NPC patient-derived xenografts and a subset of primary NPC tissues, and that knockdown of S1PR3 suppressed the activation of AKT and the S1P-induced migration of NPC cells.

  11. S1pr3 promotes leukocyte rolling by mobilization of endothelial P-selectin.

  12. Stimulation with sphingosine-1-phosphate enhances cancer stem cells via S1PR3 and subsequent Notch1 activation.

  13. TRPC1 functions as a major regulator of S1P3 and VEGFR2 expression.

  14. Data show that sphingosine kinase SphK1 and sphingosine-1-phosphate (S1P) receptors S1P1, S1P2, S1P3, and S1P5 were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 levels were highest in primary tumors.

  15. Data indicate that sphingosine 1-phosphate (S1P) and hepatocyte growth factor (HGF) induced transloaction of integrin beta4, S1P receptors S1PR2 and S1PR3 to endothelial cell membrane caveolin-enriched microdomains (CEMs).

  16. we provide evidences that S1PR1/3, but not S1PR2, negatively regulate the expression of collagen in hMSCs using cellular and molecular approaches in vitro

  17. key role of Sphk1, S1PR1 and S1PR3 in angiogenesis underlying the liver fibrosis process

  18. a novel signaling axis, i.e., ROCK-JNK-ETS-1-CD44 pathway, which plays an essential role in the S1P3-regulated chemotactic response.

  19. associations were found for 2 promoter SNPs across 2 European descent samples supporting association of alleles -1899G and -1785C with decreased risk for sepsis-associated acute respiratory distress syndrome (ARDS); alleles reduced transcription factor binding to S1PR3 promoter and S1PR3 promoter activity; associated with lower plasma S1PR3 protein in ARDS patients

  20. Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis.

Mouse (Murine) Sphingosine-1-Phosphate Receptor 3 (S1PR3) interaction partners

  1. This study identified S1P3 as a pathogenic mediator in an ischemic brain along with underlying mechanisms, involving its modulation of microglial activation and M1 polarization.

  2. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases.

  3. There is considerable sexual dimorphism in the vascular and metabolic responses of aged mice and that reduced signaling through S1PR3 could be one mechanism to explain these effects.

  4. The findings of this study demonstrated that S1P3 and Sphk1 are mediators of inflammatory signaling and are upregulated in astrocytes in response to injury.

  5. Sphingosine-1-phosphate receptor 3 (S1PR3) mediates multiple aspects of the inflammatory response during sepsis.

  6. The absence of S1P3 appears responsible for a lower availability of calcium during fatigue.

  7. These results highlight an important role for S1PR3 in Hematopoietic stem and progenitor cell niche occupancy.

  8. S1P3 deletion protects mouse soleus from age-related drop in muscle mass, force, and regenerative capacity.

  9. The finding that S1P3 receptor- and Galpha13-mediated RhoA activation is responsible for protection against ischemia/reperfusion suggests that selective targeting of S1P3 receptors could provide therapeutic benefits in ischemic heart disease.

  10. The role of the S1PR3/PDGFR-beta/Akt pathway in sphingosine-1-phosphate -induced endothelial progenitor cells migration and angiogenesis

  11. P2RY8 promotes clustering of activated B cells within follicles in a follicular dendritic cell (FDC)-dependent manner.

  12. Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P)/S1P3 signaling axis

  13. S1pr3 promotes leukocyte rolling by mobilization of endothelial P-selectin.

  14. The role of sphingosine-1-phosphate in the production of immature double-negative thymocytes in experimental and chronic Chagas disease is reported.

  15. CTGF exerts profibrotic action in myoblasts via the up-regulation of sphingosine kinase-1/S1P3 signaling axis in TGF-beta dependent manner.

  16. results indicate that S1P3 receptor signaling plays an important role in pulmonary inflammation and fibrosis and that this signaling occurs via CTGF expression

  17. key role of Sphk1, S1PR1 and S1PR3 in angiogenesis underlying the liver fibrosis process

  18. Data show that two S1P receptors, S1P2 and S1P3, are collectively essential mediators of eyelid closure during murine development.

  19. signalling though S1PR3 suppresses cell cycle progression to regulate function in muscle satellite cells

  20. This effect was not seen in the isolated tracheas from S1P(3) receptor-deficient mice.

S1PR3 抗原简介

Antigen Summary

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

Gene names and symbols associated with S1PR3

  • sphingosine-1-phosphate receptor 3 (S1PR3) 抗体
  • sphingosine-1-phosphate receptor 3a (s1pr3a) 抗体
  • sphingosine-1-phosphate receptor 3 (S1pr3) 抗体
  • AI132464 抗体
  • EDG-3 抗体
  • Edg3 抗体
  • Lpb3 抗体
  • S1p3 抗体
  • s1pr3 抗体
  • si:dkeyp-31e2.1 抗体

Protein level used designations for S1PR3

sphingosine-1-phosphate receptor 3 , sphingosine 1-phosphate receptor 3-like , G protein-coupled receptor, endothelial differentiation gene-3 , S1P receptor 3 , S1P receptor EDG3 , S1P receptor Edg-3 , endothelial differentiation G-protein coupled receptor 3 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 3 , sphingosine 1-phosphate receptor 3 , sphingosine 1-phosphate receptor Edg-3 , S1p receptor 3 , endothelial differentiation sphingolipid G-protein-coupled receptor 3 , lysophospholipid receptor B3

GENE ID SPECIES
700903 Macaca mulatta
798390 Danio rerio
100461268 Pongo abelii
100589823 Nomascus leucogenys
1903 Homo sapiens
13610 Mus musculus
306792 Rattus norvegicus
539123 Bos taurus
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