anti-Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 2 (SOHLH2) 抗体

Probable transcription factor, which may be involved in spermatogenesis and oogenesis (By similarity).. 再加上,我们可以发SOHLH2 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SOHLH2 54937 Q9NX45
SOHLH2 74434 Q9D489
SOHLH2 619575 Q3MHT3
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Showing 10 out of 52 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-SOHLH2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  OVCAR-3 cell lysate 100 μL 2至3个工作日
$289.00
详细
非结合性 WB Host: Rabbit Target Name: SOHLH2 Sample Tissue: Human MDA-MB-435s Whole Cell Antibody Dilution: 1ug/ml 100 μL 2至3个工作日
$289.00
详细
非结合性 WB Host: Rabbit Target Name: SOHLH2 Sample Type: Fetal Lung lysates Antibody Dilution: 1.0ug/ml 100 μL 2至3个工作日
$289.00
详细
Cow 非结合性 WB 100 μL 11至14个工作日
$551.83
详细
非结合性 WB Western blot analysis in MDA-MB453 cell line lysates (35ug/lane). 400 μL 2至3个工作日
$515.63
详细
非结合性 IP, WB SOHLH2 MaxPab rabbit polyclonal antibody. Western Blot analysis of SOHLH2 expression in human liver. Immunoprecipitation of SOHLH2 transfected lysate using anti-SOHLH2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with TEB1 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL 11至12个工作日
$425.71
详细
Alexa Fluor 594 IF (p)   100 μL 14至21个工作日
$428.45
详细
Cy5.5 IF (p)   100 μL 14至21个工作日
$428.45
详细
HRP IHC (p)   100 μL 14至21个工作日
$428.45
详细
Alexa Fluor 555 IF (p)   100 μL 14至21个工作日
$428.45
详细

引用最多的anti-SOHLH2 抗体

  1. Human Polyclonal SOHLH2 Primary Antibody for IF (p), IHC (p) - ABIN1713906 : Ding, Wang, Wu, Zhao, Zhang, Li: Protection of Murine Spermatogenesis Against Ionizing Radiation-Induced Testicular Injury by a Green Tea Polyphenol. in Biology of reproduction 2014 (PubMed)

更多抗SOHLH2的相互作用对抗体

Human Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 2 (SOHLH2) interaction partners

  1. Data found that sohlh2 overexpression inhibited breast cancer cell proliferation in vitro and tumor growth in vivo. In contrast, sohlh2 silencing induced the opposite effects. These functional effects of sohlh2 were exerted through inhibiting Wnt/beta- catenin signaling by the increase of APC expression. These findings provide a novel mechanistic role of sohlh2 in breast tumorigenesis.

  2. sohlh2 functions as a tumor metastasis suppressor via suppressing IL-8 expression in breast cancer

  3. Results identified MMP9 as a novel target for transcriptional inactivation by Sohlh2 and demonstrated that the Sohlh2 downregulation of MMP9 is critical for inhibiting human ovarian cancer cell invasion.

  4. the expression of Sohlh genes in human tissues

  5. The polymorphisms rs1328626 and rs6563386 of the SOHLH2 gene would be the genetic risk factors for nonobstructive azoospermia in the Chinese population. The SNP rs1328641 might influence testes development in the NOA patients.

  6. Low Sohlh2 expression is associated with ovarian cancer.

  7. Our identification of novel variants in the SOHLH2 gene, in women with POF of both Chinese and Serbian origin, strongly suggests an important role for SOHLH2 in human POF etiology.

Mouse (Murine) Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 2 (SOHLH2) interaction partners

  1. Sohlh1 and Sohlh2 are essential regulators of oocyte differentiation but do not affect meiosis I.

  2. SOHLH2 is critical for the formation of synaptonemal complexes.

  3. Sohlh2 may inhibit oocyte apoptosis via c-kit/PI3K/Akt/Foxo3a signalling pathway

  4. SOHLH1 and SOHLH2 were able to directly and cooperatively repress STRA8 expression in cell lines in vitro through binding to its promoter.

  5. Our findings suggest that an SOHLH2/SOHLH1/SP1 ternary complex autonomously and cooperatively regulates Sohlh1 gene transcription through juxtaposed E- and GC-boxes during early spermatogenesis and oogenesis.

  6. Effects of BMP4 on mouse primordial follicle growth were assayed by follicle count and TUNEL labeling. The expression of phospho-SMAD1/5/8, Sohlh2, and c-kit were measured by immunohistochemistry, RT-PCR, and Western blotting.

  7. SOHLH1 and SOHLH2 directly stimulate Kit transcription in postnatal spermatogonia, thus activating the signaling involved in spermatogonia differentiation and spermatogenetic progression.

  8. Data suggest that a dynamic DNA CpG methylation in Sohlh2 and Figlalpha promoters, but not in the intron and exon sequences, is linked to regulation of gene expression, even though CpG islands are also present in their introns or exons.

  9. SOHLH1 and SOHLH2 suppress genes involved in spermatogonial stem cell maintenance, and induce genes important for spermatogonial differentiation.

  10. The expression pattern of SOHLH2 suggests that it may be a critical regulator of early germ cell development.

  11. Knockout of this protein causes degegneration of spermatogonia in mice.

  12. Sohlh2 is a critical factor for maintenance and differentiation of the oocyte during early oogenesis

  13. SOHLH2 might coordinate with SOHLH1 to control spermatogonial and oocyte genes, including Sohlh1, to promote the differentiation of KIT(+) germ cells in vivo.

SOHLH2 抗原简介

蛋白简介

Probable transcription factor, which may be involved in spermatogenesis and oogenesis (By similarity).

Gene names and symbols associated with SOHLH2

  • spermatogenesis and oogenesis specific basic helix-loop-helix 2 (SOHLH2) 抗体
  • spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 (LOC100443062) 抗体
  • spermatogenesis and oogenesis specific basic helix-loop-helix 2 (Sohlh2) 抗体
  • 4933406N12Rik 抗体
  • AI413378 抗体
  • bHLHe81 抗体
  • RGD1304752 抗体
  • SPATA28 抗体
  • TEB1 抗体

Protein level used designations for SOHLH2

spermatogenesis and oogenesis specific basic helix-loop-helix 2 , spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2-like , spermatogenesis associated 28 , spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2

GENE ID SPECIES
452536 Pan troglodytes
486009 Canis lupus familiaris
518810 Bos taurus
693608 Macaca mulatta
100443062 Pongo abelii
100580067 Nomascus leucogenys
54937 Homo sapiens
74434 Mus musculus
619575 Rattus norvegicus
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