SPATA13 抗体
(Spermatogenesis Associated 13 (SPATA13))
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA (By similarity). Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
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20 results
SPATA13
适用: 人
WB, ELISA, IHC, FACS
宿主: 兔
Polyclonal
unconjugated
Aliases for SPATA13 抗体
spermatogenesis associated 13 (SPATA13) 抗体spermatogenesis associated 13 (Spata13) 抗体
ARHGEF29 抗体
ASEF2 抗体
C79050 抗体
ESTM11 抗体
mFLJ00298 抗体
X83327 抗体
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