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Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. 再加上，我们可以发SPAG16 抗体 (72) 和 和数多这个蛋白质的别的产品。
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Short-SOX5 regulates transcription of human SPAG16L gene via directly binding to the promoter of SPAG16L.
SPAG16 is a novel autoantibody target in a subgroup of MS patients and in combination with other diagnostic criteria, elevated levels of anti-SPAG16 Abs could be used as a biomarker for diagnosis.
SPAG16 influences MMP-3 regulation and protects against joint destruction in autoantibody-positive rheumatoid arthritis.
Analysis of SPAG16 regions encoding conserved WD repeats revealed no evidence for association of mutations or genetic variation with sperm motility in infertile males.
Data describe the cloning of human and mouse Pf20 proteins that interact with Spag6 protein.
Heterozygous mutation that affects both SPAG16L and SPAG16S does not cause male infertility in man, but is associated with reduced stability of the interacting proteins of the central apparatus.
The distinct nuclear localization of SPAG16S and its ability to modulate Spag16L mRNA expression suggest that SPAG16S plays an important role in the gene expression machinery of male germ cells.
Functional deficiencies and a reduced response to calcium in the flagellum of mouse sperm lacking SPAG16L.
In sperm, SPAG16L is found in the central apparatus of the axoneme. We conclude that SPAG16L is essential for sperm flagellar function.
SPAG16L can be phosphorylated by TSSK2 in vitro.
Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007
sperm associated antigen 16
, WD repeat domain 29
, pf20 protein homolog
, sperm-associated WD repeat protein
, sperm-associated antigen 16 protein