Sperm Associated Antigen 11B 蛋白 (SPAG11B)

SPAG11B encodes several androgen-dependent, epididymis-specific secretory proteins. 再加上,我们可以发Sperm Associated Antigen 11B 抗体 (9)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
SPAG11B 10407 Q6PDA7 , Q08648
大鼠 SPAG11B SPAG11B 246305 Q8VBV2
SPAG11B 546038 Q8K4N2
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
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SPAG11B 蛋白 by Origin and Source

Origin 在表达 标记
Human ,
,
Mouse (Murine)

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Human Sperm Associated Antigen 11B (SPAG11B) interaction partners

  1. we report the three dimensional structure of the human SPAG11B proteins and their C-terminal peptides. web-based hydropathy, amphipathicity, and topology (WHAT) analyses and grand average of hydropathy

  2. Isoform C of SPAG11B encodes a peptide with antimicrobial activity against E. coli.

  3. Combination of two proteins, SPAG11B and TEX101, can be used for differential diagnosis of azoospermia

  4. SPAG11B/D is both a substrate and a potent inhibitor of TPSAB1 (显示 TPSAB1 蛋白) activity.

  5. HE2 peptides were detected in human epididymal epithelium, epididymal fluid, and ejaculate

  6. HE2 transcriptional and translational products normally expressed in the caput epididymidis were not affected by vasectomy.

  7. EP2 expression is more widespread in male reproductive tract than realized previously. Activity of every EP2 variant tested is antibacterial. Further investigation may reveal additional roles for EP2 peptides in primate male reproductive tract.

  8. In the chimpanzee epididymis, several mRNA HE2/EP2 variants are produced. Of these, three cDNAs code for two different protein sequences that have a cysteine distribution characteristic for beta-defensins.

  9. The human HE2/EP2 gene is the fusion product of two ancestral beta-defensin (显示 DEFB1 蛋白) genes. During its evolution, the gene has acquired additional exons whose inclusion produces new message variants that encode peptides unrelated to defensins.

Mouse (Murine) Sperm Associated Antigen 11B (SPAG11B) interaction partners

  1. Data suggest that Spag11a (显示 SPAG11A 蛋白) has a specific role in epididymal sperm maturation.

  2. Model was developed in which Bin1b (显示 SPAG11A 蛋白) was exclusively overexpressed by up to 50-fold in the caput epididymis. The transgenic mice are healthy with normal reproductive activity, but are more resistant to epididymal infection from E coli than normal animals.

  3. The epididymis-specific expression pattern of the beta-defensin (显示 DEFB1 蛋白) isoform EP2e (显示 SPAG11A 蛋白) has been characterized.

Cow (Bovine) Sperm Associated Antigen 11B (SPAG11B) interaction partners

  1. SPAG11 (显示 SPAG11A 蛋白) isoforms perform both immune and reproductive functions in cattle.

蛋白简介Sperm Associated Antigen 11B (SPAG11B)

蛋白简介

This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined.

Gene names and symbols associated with SPAG11B

  • sperm associated antigen 11B (SPAG11B)
  • sperm associated antigen 11A (Spag11a)
  • sperm associated antigen 11B (Spag11b)
  • 9230111C08Rik 蛋白
  • Bin1b 蛋白
  • EDDM2B 蛋白
  • EG546038 蛋白
  • EP2 蛋白
  • EP2C 蛋白
  • Ep2c/h 蛋白
  • EP2D 蛋白
  • EP2e 蛋白
  • EP2Q 蛋白
  • HE2 蛋白
  • HE2C 蛋白
  • Spag11 蛋白
  • SPAG11B 蛋白
  • Spag11c/h 蛋白

Protein level used designations for SPAG11B

epididymal protein 2B , human epididymis-specific protein 2 , sperm antigen HE2 , sperm-associated antigen 11B , anti-microbial-like protein BIN-1B , antimicrobial-like protein Bin-1b , sperm associated antigen 11 , sperm-associated antigen 11 , beta-defensin-like peptide , sperm-associated antigen 11c/h , sperm associated antigen 11B , antimicrobial peptide Bin1b , beta defensin EP2e

GENE ID SPECIES
10407 Homo sapiens
246305 Rattus norvegicus
546038 Mus musculus
783025 Bos taurus
100188900 Sus scrofa
78128 Mus musculus
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