Sperm Associated Antigen 1 蛋白
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization.
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Sperm Associated Antigen 1 (SPAG1) (AA 1-926) protein (His tag) Protein
Sperm Associated Antigen 1 (SPAG1) (AA 1-901) protein (His tag) Protein
Sperm Associated Antigen 1 (SPAG1) (AA 1-365) protein (T7 tag,His tag) Protein
Sperm Associated Antigen 1 (SPAG1) (AA 175-283) protein (GST tag) Protein
Sperm Associated Antigen 1 (SPAG1) 蛋白 Protein
Sperm Associated Antigen 1 (SPAG1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
蛋白简介Sperm Associated Antigen 1 (SPAG1)
蛋白简介
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
Gene names and symbols associated with SPAG1
- sperm associated antigen 1 (SPAG1) 抗体
- sperm associated antigen 1a (spag1a) 抗体
- sperm associated antigen 1 (CpipJ_CPIJ006297) 抗体
- sperm associated antigen 1 (spag1) 抗体
- sperm associated antigen 1 (Spag1) 抗体
- cb1089 抗体
- HSD-3.8 抗体
- MGC162178 抗体
- SP75 抗体
- TPIS 抗体
- wu:fj78g10 抗体
Protein level used designations for SPAG1
sperm associated antigen 1 , sperm-associated antigen 1 , TPR-containing protein involved in spermatogenesis , infertility-related sperm protein Spag-1 , tetratricopeptide repeat-containing protein , HSD-3.8
| GENE ID | SPECIES |
|---|---|
| 420249 | Gallus gallus |
| 464314 | Pan troglodytes |
| 564953 | Danio rerio |
| 607063 | Canis lupus familiaris |
| 6038177 | Culex quinquefasciatus |
| 100038144 | Xenopus (Silurana) tropicalis |
| 6674 | Homo sapiens |
| 26942 | Mus musculus |
| 315033 | Rattus norvegicus |
| 530104 | Bos taurus |
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