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SPAM1 蛋白

Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes.

10 results:

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 36-490) protein (His tag) Protein

SPAM1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
产品编号 ABIN3081716
$10,832.86
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping 发货至: 美国
60个工作日

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 1-509) protein (GST tag) Protein

SPAM1 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
产品编号 ABIN1321070
$498.33
Plus shipping costs $45.00 and $24.00 dry ice
2 μg
local_shipping 发货至: 美国
11至12个工作日

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

SPAM1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
产品编号 ABIN2732494
$504.90
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping 发货至: 美国
11个工作日

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 346-445) protein (GST tag) Protein

SPAM1 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
产品编号 ABIN1321072
$574.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping 发货至: 美国
11至12个工作日

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) protein (His tag) Protein

SPAM1 宿主: 人 宿主: HEK-293 Cells Recombinant ≥92 % by SDS-PAGE HPLC, SDS
产品编号 ABIN1888707
$1,025.00
加上运输费 $45.00
50 μg (More quantities available)
local_shipping 发货至: 美国
2至3个工作日

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 36-482) protein (His tag) Protein

SPAM1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2181785
$1,375.00
加上运输费 $45.00
200 μg (More quantities available)
local_shipping 发货至: 美国
2至3个工作日
产品编号 ABIN6964321
$433.23
加上运输费 $45.00
100 μg
local_shipping 发货至: 美国
17至18个工作日

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) protein (His tag) Protein

SPAM1 宿主: 人 宿主: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. WB
产品编号 ABIN2566867
$639.38
加上运输费 $45.00
0.025 mg
local_shipping 发货至: 美国
2至3个工作日

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 36-491) protein (His tag) Protein

SPAM1 宿主: Cynomolgus 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1610527
$3,281.67
加上运输费 $45.00
1 mg
local_shipping 发货至: 美国
57至68个工作日

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 36-492) protein (His tag) Protein

SPAM1 宿主: 豚鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1461869
$3,285.33
加上运输费 $45.00
1 mg
local_shipping 发货至: 美国
57至68个工作日
  • 类型 Protein
    • Protein
  • 抗原 Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1)
    • Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Growth Hormone 1 (GH1)
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Interleukin 8 (IL8)
    • Leptin (LEP)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • CD40 Ligand (CD40LG)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Interleukin 33 (IL33)
    • SARS-CoV-2 Spike S1
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Adiponectin (ADIPOQ)
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • SDS-PAGE (SDS)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • High Pressure Liquid Chromatography (HPLC)
    • Protein Interaction (PI)
    • Standard (STD)
    • Crystallization (Crys)
  • 适用
    • Cynomolgus
    • 豚鼠
  • 图像
  • 抗体来源
    • HEK-293 Cells
    • 小麦胚
    • 酵母菌
    • Insect Cells
  • 抗原表位
    • AA 1-509
    • AA 346-445
    • AA 36-482
    • AA 36-490
    • AA 36-491
    • AA 36-492
    • Transcript Variant 1
  • 标记
    • 非结合性
    • His tag
    • GST tag
    • Fc Tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid

蛋白简介SPAM1

蛋白简介

Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1\; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPAM1

  • sperm adhesion molecule 1 (Spam1) 抗体
  • sperm adhesion molecule 1 (SPAM1) 抗体
  • sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L homeolog (spam1.L) 抗体
  • sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) (SPAM1) 抗体
  • sperm adhesion molecule 1 (spam1) 抗体
  • AV039194 抗体
  • HYA1 抗体
  • HYAL1 抗体
  • HYAL3 抗体
  • HYAL5 抗体
  • im:6902904 抗体
  • PH-20 抗体
  • PH20 抗体
  • SPAG15 抗体
  • Spam 抗体
  • spam1 抗体
  • XEH1 抗体
  • zgc:158668 抗体

Protein level used designations for SPAM1

hyal-PH20 , hyaluronidase PH-20 , hyaluronoglucosaminidase PH-20 , sperm surface protein PH-20 , sperm protein PH-20 , PH-20 protein , sperm surface antigen 2B1 , hyaluronidase , sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L homeolog , hyaluronidase, zona pellucida binding , sperm adhesion molecule 1

GENE ID SPECIES
20690 Mus musculus
100135624 Cavia porcellus
6677 Homo sapiens
100009391 Oryctolagus cuniculus
117037 Rattus norvegicus
398285 Xenopus laevis
353352 Bos taurus
791203 Danio rerio

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