anti-Sp7 Transcription Factor (SP7) 抗体

SP7 encodes a member of the Sp subfamily of Sp/XKLF transcription factors. 再加上,我们可以发SP7 试剂盒 (26)SP7 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SP7 121340 Q8TDD2
SP7 300260  
SP7 170574 Q8VI67
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • 在线下订单

antibodies-online.cn销售最多的anti-SP7 抗体

Showing 10 out of 37 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB Immunohistochemistry with Testis tissue at an antibody concentration of 5µg/ml using anti-SP7 antibody (ARP32231_P050) 100 μL Log in to see 2至3个工作日
Cow 非结合性 IHC, WB Host: Rabbit <br /> Target Name: SP7 <br /> Sample Tissue: Jurkat Whole Cell lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2至3个工作日
Cow 非结合性 WB Host: Rabbit <br /> Target Name: Sp7 <br /> Sample Tissue: Rat Testis lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2至3个工作日
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti Osterix Polyclonal Antibody, Unconjugated (ABIN737811) at 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse spinal cord lysates probed with Osterix Polyclonal Antibody, unconjugated  at 1:300 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C. 100 μL Log in to see 3至7个工作日
Cow 非结合性 WB WB Suggested Anti-SP7 Antibody Titration: 2.5 ug/ml Positive Control: Jurkat Whole Cell 100 μL Log in to see 2至3个工作日
Cow 非结合性 WB 100 μg Log in to see 7至9个工作日
Cow 非结合性 IHC, WB 50 μg Log in to see 7至9个工作日
小鼠 PE ICC, WB Western Blot (Negative): Osterix/Sp7 Antibody (764704) [PE] [NBP2-47615PE] - Analysis in Saos-2 human osteosarcoma cell line. Experiment was done in reducing conditions. Immunocytochemistry/Immunofluorescence: Osterix/Sp7 Antibody (764704) [PE] [NBP2-47615PE] - Analysis in Saos-2 human osteosarcoma cell line. Specific staining was localized to nuclei. 0.1 mL Log in to see 10至13个工作日
小鼠 非结合性 ELISA, WB Detection limit for recombinant GST tagged SP7 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8至11个工作日
非结合性 ELISA, IHC, WB 0.1 mg Log in to see 2至6个工作日

通过反应活性、应用领域、克隆类型和共轭标记 SP7 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , , ,
, , , , , , , , , , , , , ,
Rat (Rattus) , ,

, , , , , , , , , , , , ,
Mouse (Murine) , ,

, , , , , , , , , , , , ,

引用最多的anti-SP7 抗体

  1. Human Polyclonal SP7 Primary Antibody for IF (p), IHC (p) - ABIN737811 : Chen, Lazarenko, Zhang, Blackburn, Ronis, Badger: Diet-derived phenolic acids regulate osteoblast and adipocyte lineage commitment and differentiation in young mice. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 (PubMed)
    Show all 11 Pubmed References

  2. Cow (Bovine) Polyclonal SP7 Primary Antibody for IHC, WB - ABIN2777381 : Milona, Gough, Edgar: Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cells. in BMC genomics 2004 (PubMed)


Human Sp7 Transcription Factor (SP7) interaction partners

  1. Results provide evidence that CBP (显示 CREBBP 抗体)-mediated acetylation and HDAC4 (显示 HDAC4 抗体)-mediated deacetylation have critical roles in the modification of Osx (显示 MID1 抗体), and thus are important in osteoblast differentiation.

  2. Osterix and RUNX2 (显示 RUNX2 抗体) are transcriptional regulators of sclerostin (显示 SOST 抗体) in human bone

  3. Osterix decreased the chemosensitivity of breast cancer cells by upregulating the expression of GALNT14 (显示 GALNT14 抗体), which eventually suppressed the apoptosis of breast cancer cells.

  4. TP(thymidine phosphorylase (显示 TYMP 抗体) ) curbed the expression of three proteins-IRF8 (显示 IRF8 抗体), RUNX2 (显示 RUNX2 抗体), and osterix. This downregulation was epigenetically driven: High levels of 2DDR, a product of TP secreted by myeloma cells, activated PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体) signaling and increased the methyltransferase DNMT3A's expression

  5. dissection of these interconnected epigenetic mechanisms that govern Sp7 gene activation reveals a hierarchical process where regulatory components mediating DNA demethylation play a leading role

  6. SP7 gene promoter is robustly enriched in epigenetic repressive marks that may explain its poor transcriptional response to osteoblast differentiating media in umbilical cord derived mesenchymal stem cells.

  7. Eight and five of the nine samples were negative for cell adhesion molecule 1 (显示 CADM1 抗体) and Osterix respectively. The other markers showed no statistical significance(CD151 (显示 CD151 抗体),ALP (显示 ALP 抗体)). osteoblastic differentiation can occur in carcinoma cells and that cell adhesion molecule 1 (显示 CADM1 抗体) could be a useful marker for identifying this phenomenon in carcinoma tissues

  8. The results suggest that Osterix plays an important role in increasing BMP- 4 (显示 BMP4 抗体)-induced Cx43 (显示 GJA1 抗体) activity.

  9. The expression of specific targets Smad1 (显示 GARS 抗体) and Osterix was significantly increased in the presence of Pi and restored by coincubation with Mg(2 (显示 MUC7 抗体)+). As miR (显示 MLXIP 抗体)-30b, miR (显示 MLXIP 抗体)-133a, and miR (显示 MLXIP 抗体)-143 are negatively regulated by Pi and restored by Mg(2 (显示 MUC7 抗体)+) with a congruent modulation of their known targets Runx2 (显示 RUNX2 抗体), Smad1 (显示 GARS 抗体), and Osterix, our results provide a potential mechanistic explanation of the observed upregulation of these master switches of o

  10. Preameloblast-Derived Factors Mediate Osteoblast Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Runx2 (显示 RUNX2 抗体)-Osterix-BSP (显示 KLK6 抗体) Signaling.

Zebrafish Sp7 Transcription Factor (SP7) interaction partners

  1. Sp7 plays a critical role in limiting the level of signaling and the rate of bone growth

  2. FGF and Wnt (显示 WNT2 抗体)/beta-Catenin (显示 CTNNB1 抗体) pathways act in part by directing transcription of osx to promote osteoblast differentiation at sites of bone formation.

  3. Data show the endogenous sp7 gene expression in the otic placode and vesicle, and in forming skeletal structures in Tg(sp7:EGFP)b1212 line.

Mouse (Murine) Sp7 Transcription Factor (SP7) interaction partners

  1. These results suggest proliferation and maturation of immature osteoblasts requires Tgfbr2 (显示 TGFBR2 抗体) signaling and that decreased bone volume in Osx-Cre;Tgfbr2 (显示 TGFBR2 抗体)(fl/fl (显示 FLT3LG 抗体)) mice is likely due to fewer mature osteoblasts.

  2. DNA damage and senescence in osteoprogenitors expressing Osx may cause their decrease with age.

  3. The data support a model in which Dlx recruitment of Sp7 to osteoblast enhancers underlies Sp7-directed osteoblast specification.

  4. Mmp13 (显示 MMP13 抗体) is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (显示 PTH 抗体), and Osterix through distal enhancers.

  5. These results indicated that olfactory bulb development was not significantly impaired in the absence of Osx.

  6. Wnt3a (显示 WNT3A 抗体) induces Osx expression via p38 MAPK (显示 MAPK14 抗体) signaling in dental follicle cells. Wnt3a (显示 WNT3A 抗体)-induced Osx expression was inhibited in the presence of p38 mitogen-activated protein kinase (显示 MAPK14 抗体) (MAPK (显示 MAPK1 抗体)) inhibitors (SB203580 and SB202190) at gene and protein levels, as assessed by real-time PCR and immunocytohistochemistry, respectively.

  7. Transfection assay demonstrated that Osx was able to activate Bsp (显示 KLK6 抗体) promoter reporter in a dose-dependent manner. To define minimal region of Bsp (显示 KLK6 抗体) promoter activated by Osx, a series of deletion mutants of Bsp (显示 KLK6 抗体) promoter were generated, and the minimal region was narrowed down to the proximal 100 bp. Point-mutagenesis studies showed that one GC-rich (显示 RELB 抗体) site was required for Bsp (显示 KLK6 抗体) promoter activation by Osx.

  8. OSX served a key role in the development and progression of ALD (显示 ABCD1 抗体)-induced VSMC calcification. This observation may aid in the explanation of the role of OSX in the pathogenesis of vascular calcification

  9. results suggest that expression of Sp7 during the early stage of Satb2 (显示 SATB2 抗体)-induced osteogenic differentiation of BMSCs is regulated by miR (显示 MLXIP 抗体)-27a.

  10. Fibrillin-2 (显示 FBN2 抗体) and periostin (显示 POSTN 抗体) are target genes in Osterix-mediated osteoblast differentiation.

SP7 抗原简介


This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.

Gene names and symbols associated with SP7

  • Sp7 transcription factor (SP7) 抗体
  • Sp7 transcription factor (Sp7) 抗体
  • Sp7 transcription factor (sp7) 抗体
  • uncharacterized LOC100063836 (LOC100063836) 抗体
  • Sp7 transcription factor L homeolog (sp7.L) 抗体
  • Sp7 transcription factor 7 (Sp7) 抗体
  • 6430578P22Rik 抗体
  • C22 抗体
  • OI11 抗体
  • OI12 抗体
  • osterix 抗体
  • osx 抗体
  • sp7 抗体

Protein level used designations for SP7

transcription factor Sp7 , zinc finger protein osterix , osterix , transcription factor osterix , Sp7 transcription factor , transcription factor Sp7-like , trans-acting transcription factor 7 , Sp7 transcription factor 7

121340 Homo sapiens
300260 Rattus norvegicus
405789 Danio rerio
467004 Pan troglodytes
531995 Bos taurus
607857 Canis lupus familiaris
702575 Macaca mulatta
100063836 Equus caballus
100101324 Xenopus laevis
100189548 Xenopus (Silurana) tropicalis
100407102 Callithrix jacchus
100587177 Nomascus leucogenys
170574 Mus musculus
404701 Sus scrofa
100732690 Cavia porcellus
anti-SP7 (SP7) 抗体 精选生产商