anti-Sp7 Transcription Factor (SP7) 抗体

SP7 encodes a member of the Sp subfamily of Sp/XKLF transcription factors. 再加上,我们可以发SP7 试剂盒 (26)SP7 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SP7 121340 Q8TDD2
SP7 300260  
SP7 170574 Q8VI67
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antibodies-online.cn销售最多的anti-SP7 抗体

Showing 10 out of 45 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB Host:  Rabbit  Target Name:  SP7  Sample Type:  Jurkat Whole Cell lysates  Antibody Dilution:  1.0ug/ml Host:  Rabbit  Target Name:  SP7  Sample Type:  Jurkat Whole Cell lysates  Antibody Dilution:  0.5ug/ml 100 μL Log in to see 2至3个工作日
$319.00
详细
Cow 非结合性 IHC, WB Immunohistochemistry with Testis tissue at an antibody concentration of 5µg/ml using anti-SP7 antibody (ARP32231_P050) Host:  Rabbit  Target Name:  SP7  Sample Tissue:  Human Fetal Lung  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2至3个工作日
$319.00
详细
Cow 非结合性 WB Host:  Rabbit  Target Name:  Sp7  Sample Type:  Rat Testis lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti Osterix Polyclonal Antibody, Unconjugated (ABIN737811) at 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse spinal cord lysates probed with Osterix Polyclonal Antibody, unconjugated  at 1:300 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C. 100 μL Log in to see 3至7个工作日
$318.45
详细
Cow 非结合性 WB WB Suggested Anti-SP7 Antibody Titration: 2.5 ug/ml Positive Control: Jurkat Whole Cell 100 μL Log in to see 2至3个工作日
$229.00
详细
Cow 非结合性 WB 100 μg Log in to see 7至9个工作日
$493.17
详细
Cow 非结合性 IHC, WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 ELISA, WB Western blot analysis of Osterix using K562 whole  lysates. 100 μL Log in to see 11至12个工作日
$390.77
详细
非结合性 ELISA, WB Western blot analysis of Phospho-osterix(Thr319) in lysates of 293T, using Phospho-osterix(Thr319) Antibody(ABIN6269578). 100 μL Log in to see 11至12个工作日
$450.00
详细
小鼠 PE ICC, WB Western Blot (Negative): Osterix/Sp7 Antibody (764704) [PE] [NBP2-47615PE] - Analysis in Saos-2 human osteosarcoma cell line. Experiment was done in reducing conditions. Immunocytochemistry/Immunofluorescence: Osterix/Sp7 Antibody (764704) [PE] [NBP2-47615PE] - Analysis in Saos-2 human osteosarcoma cell line. Specific staining was localized to nuclei. 0.1 mL Log in to see 34 Days
$556.31
详细

引用最多的anti-SP7 抗体

  1. Human Polyclonal SP7 Primary Antibody for IF (p), IHC (p) - ABIN737811 : Chen, Lazarenko, Zhang, Blackburn, Ronis, Badger: Diet-derived phenolic acids regulate osteoblast and adipocyte lineage commitment and differentiation in young mice. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 (PubMed)
    Show all 11 Pubmed References

  2. Human Polyclonal SP7 Primary Antibody for ELISA, WB - ABIN6263914 : Zhang, Xie, Wang, Zhang, Yang: Anti-osteoporosis activity of Sanguinarine in preosteoblast MC3T3-E1 cells and an ovariectomized rat model. in Journal of cellular physiology 2018 (PubMed)

  3. Cow (Bovine) Polyclonal SP7 Primary Antibody for IHC, WB - ABIN2777381 : Milona, Gough, Edgar: Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cells. in BMC genomics 2004 (PubMed)

更多抗SP7的相互作用对抗体

Human Sp7 Transcription Factor (SP7) interaction partners

  1. Data support a model wherein p53 (显示 TP53 抗体) represses OSX (显示 MID1 抗体)-DNA binding and DLX5 (显示 DLX5 抗体)-OSX (显示 MID1 抗体) interaction, and thereby deregulates the osteogenic transcriptional network.

  2. Results showed that blocking miR (显示 MLXIP 抗体)-31 led to an increase in osterix protein in both cell types at day 7, with an increase in osteocalcin (显示 BGLAP 抗体) at day 21, suggesting MSC (显示 MSC 抗体) osteogenesis

  3. Results provide evidence that CBP (显示 CREBBP 抗体)-mediated acetylation and HDAC4 (显示 HDAC4 抗体)-mediated deacetylation have critical roles in the modification of Osx (显示 MID1 抗体), and thus are important in osteoblast differentiation.

  4. Osterix and RUNX2 (显示 RUNX2 抗体) are transcriptional regulators of sclerostin (显示 SOST 抗体) in human bone

  5. Osterix decreased the chemosensitivity of breast cancer cells by upregulating the expression of GALNT14 (显示 GALNT14 抗体), which eventually suppressed the apoptosis of breast cancer cells.

  6. TP(thymidine phosphorylase (显示 TYMP 抗体) ) curbed the expression of three proteins-IRF8 (显示 IRF8 抗体), RUNX2 (显示 RUNX2 抗体), and osterix. This downregulation was epigenetically driven: High levels of 2DDR, a product of TP secreted by myeloma cells, activated PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体) signaling and increased the methyltransferase DNMT3A's expression

  7. dissection of these interconnected epigenetic mechanisms that govern Sp7 gene activation reveals a hierarchical process where regulatory components mediating DNA demethylation play a leading role

  8. SP7 gene promoter is robustly enriched in epigenetic repressive marks that may explain its poor transcriptional response to osteoblast differentiating media in umbilical cord derived mesenchymal stem cells.

  9. Eight and five of the nine samples were negative for cell adhesion molecule 1 (显示 CADM1 抗体) and Osterix respectively. The other markers showed no statistical significance(CD151 (显示 CD151 抗体),ALP (显示 ALP 抗体)). osteoblastic differentiation can occur in carcinoma cells and that cell adhesion molecule 1 (显示 CADM1 抗体) could be a useful marker for identifying this phenomenon in carcinoma tissues

  10. The results suggest that Osterix plays an important role in increasing BMP- 4 (显示 BMP4 抗体)-induced Cx43 (显示 GJA1 抗体) activity.

Zebrafish Sp7 Transcription Factor (SP7) interaction partners

  1. In zebrafish lacking sp7, attachment bone is never present, independent of the stage of tooth development or fish age, yet replacement is not interrupted. There was abnormal orientation of teeth, and abnormal connection of pulp cavities of predecessor and replacement teeth, arrested dentinogenesis, non-polarization of odontoblasts and only a thin layer of dentin deposition.

  2. Sp7 plays a critical role in limiting the level of signaling and the rate of bone growth

  3. FGF and Wnt (显示 WNT2 抗体)/beta-Catenin (显示 CTNNB1 抗体) pathways act in part by directing transcription of osx to promote osteoblast differentiation at sites of bone formation.

  4. Data show the endogenous sp7 gene expression in the otic placode and vesicle, and in forming skeletal structures in Tg(sp7:EGFP)b1212 line.

Mouse (Murine) Sp7 Transcription Factor (SP7) interaction partners

  1. beta-catenin (显示 CTNNB1 抗体) in osterix-expressing cells is required for postnatal osteoblast differentiation, osteoblast proliferation, and bone resorption, and is essential for the anabolic actions of parathyroid hormone (显示 PTH 抗体) in bone.

  2. Mullerian duct(MD) regression was delayed in Osx-null males, identifying Osx as a factor that regulates MD regression.

  3. Results indicate that Dlx5 (显示 DLX5 抗体) and Runx2 (显示 RUNX2 抗体) are critical factors for the upregulated Osterix expression in shPP2A cells, which is considered to be important for the accelerated osteoblast differentiation in these cells.

  4. Data support a model wherein p53 (显示 TP53 抗体) represses OSX-DNA binding and DLX5 (显示 DLX5 抗体)-OSX interaction, and thereby deregulates the osteogenic transcriptional network.

  5. this study shows that Osterix represses adipogenesis by negatively regulating PPARgamma (显示 PPARG 抗体) transcriptional activity

  6. these findings strongly suggest that TGF-beta (显示 TGFB1 抗体) signaling plays a major role as one of the upstream regulators of Osx in cementoblast differentiation and cementum formation

  7. These results suggest proliferation and maturation of immature osteoblasts requires Tgfbr2 (显示 TGFBR2 抗体) signaling and that decreased bone volume in Osx-Cre;Tgfbr2 (显示 TGFBR2 抗体)(fl/fl (显示 FLT3LG 抗体)) mice is likely due to fewer mature osteoblasts.

  8. DNA damage and senescence in osteoprogenitors expressing Osx may cause their decrease with age.

  9. The data support a model in which Dlx recruitment of Sp7 to osteoblast enhancers underlies Sp7-directed osteoblast specification.

  10. Mmp13 (显示 MMP13 抗体) is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (显示 PTH 抗体), and Osterix through distal enhancers.

SP7 抗原简介

蛋白简介

This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.

Gene names and symbols associated with SP7

  • Sp7 transcription factor (SP7) 抗体
  • Sp7 transcription factor (Sp7) 抗体
  • Sp7 transcription factor (sp7) 抗体
  • uncharacterized LOC100063836 (LOC100063836) 抗体
  • Sp7 transcription factor L homeolog (sp7.L) 抗体
  • Sp7 transcription factor 7 (Sp7) 抗体
  • 6430578P22Rik 抗体
  • C22 抗体
  • OI11 抗体
  • OI12 抗体
  • osterix 抗体
  • osx 抗体
  • sp7 抗体

Protein level used designations for SP7

transcription factor Sp7 , zinc finger protein osterix , osterix , transcription factor osterix , Sp7 transcription factor , transcription factor Sp7-like , trans-acting transcription factor 7 , Sp7 transcription factor 7

GENE ID SPECIES
121340 Homo sapiens
300260 Rattus norvegicus
405789 Danio rerio
467004 Pan troglodytes
531995 Bos taurus
607857 Canis lupus familiaris
702575 Macaca mulatta
100063836 Equus caballus
100101324 Xenopus laevis
100189548 Xenopus (Silurana) tropicalis
100407102 Callithrix jacchus
100587177 Nomascus leucogenys
170574 Mus musculus
404701 Sus scrofa
100732690 Cavia porcellus
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