SNX18 encodes a member of the sorting nexin family. 再加上，我们可以发SNX18 蛋白 (5) 和 和数多这个蛋白质的别的产品。
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Human Polyclonal SNX18 Primary Antibody for ELISA - ABIN547053
Teasdale, Loci, Houghton, Karlsson, Gleeson: A large family of endosome-localized proteins related to sorting nexin 1. in The Biochemical journal 2001
We propose a model where upon autophagy induction, SNX18 recruits Dynamin-2 to induce budding of ATG9A and ATG16L1 containing membranes from recycling endosomes that traffic to sites of autophagosome formation.
SNX18 promotes autophagosome formation by virtue of its ability to remodel membranes and provide membrane to forming autophagosomes.
The sorting nexin 9 (SNX9) subfamily members - SNX9, SNX18 and SNX33 - are required for progression and completion of mitosis.
FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells.
functions in multiple pathways of endocytosis at the plasma membrane
The results indicate that SNX9-family members make up discrete membrane-scission units together with dynamin, and suggest that SNX18 mediates budding of carriers for AP-1-positive endosomal trafficking.
SNX18 may play an active role in axonal elongation
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene.
sorting nexin 18
, sorting nexin associated golgi protein 1
, sorting nexin-18
, sorting nexin-18-like
, SH3 and PX domain-containing protein 3B
, sorting nexin-associated Golgi protein 1