This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Ma, Robinson, Chircop: "Sorting nexin 9 recruits clathrin heavy chain to the mitotic spindle for chromosome alignment and segregation." in: PLoS ONE, Vol. 8, Issue 7, pp. e68387, (2013) (PubMed).
Teasdale, Loci, Houghton, Karlsson, Gleeson: "A large family of endosome-localized proteins related to sorting nexin 1." in: The Biochemical journal, Vol. 358, Issue Pt 1, pp. 7-16, (2001) (PubMed).