Somatostatin Receptor 3 蛋白 (SSTR3)

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. 再加上,我们可以发Somatostatin Receptor 3 抗体 (34)Somatostatin Receptor 3 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
SSTR3 6753 P32745
SSTR3 20607 P30935
大鼠 SSTR3 SSTR3 171044 P30936
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Showing 5 out of 5 products:

产品编号 Origin 资源 标记 图像 规格 交付 价格 详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 50至55个工作日
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30至35个工作日
大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30至35个工作日
Insect Cells rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50至55个工作日
小麦胚 GST tag 2 μg 11至12个工作日

SSTR3 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Mouse (Murine) ,

更多Somatostatin Receptor 3 (SSTR3)互动伙伴

Human Somatostatin Receptor 3 (SSTR3) interaction partners

  1. the C-terminal phosphorylation motif of the human sst3 receptor that regulates its agonist-promoted phosphorylation, beta-arrestin recruitment, and internalization of this clinically relevant receptor, is reported.

  2. Data showed that the distribution of somatostatin receptor (SSTR) subtypes among the 199 pancreatic neuroendocrine tumors (PNETs) was: SSTR2 (54.8%), SSTR1 (53.3%), SSTR4 (51.8%), SSTR5 (33.7%), and SSTR3 (28.6%).

  3. Data indicate that somatostatin receptor scintigraphy (SRS) and immunohistochemical results for somatostatin and dopamine receptors sstr2, sstr3, sstr5 and D2R were compared in neuroendocrine neoplasms tissues.

  4. findings provide new insights in understanding the antiproliferative role of SSTR3 in breast tumor biology.

  5. An immunohistochemical investigation of the expression of somatostatin receptor subtypes

  6. In conclusions, in CNFAs, high expression of somatostatin receptors is much less common than that of D2R

  7. SSTR2A and SSTR3 are more likely to be expressed in SDH-deficient pheochromocytomas/paragangliomas compared with tumors demonstrating normal SDHB staining pattern.

  8. constitutive SSTR3 activity mediates transcriptional repression of GH.

  9. High SSTR3 expression is associated with gallbladder cancer.

  10. Determination of the expression of SSTR3 in an attempt to establish correlations and/or associations with clinical characteristics of patients with nonfunctioning pituitary adenomas.

  11. mRNA levels of SSTR2a, SSTR3 and SSTR5 in neuroendocrine lung cancer affected patients, were determined

  12. Data show that the mRNA levels of SSTR1, SSTR2, SSTR3, and SSTR5 were high in PET compared with AC, whereas the expression of SSTR4 was low in PET and AC.

  13. Studies show that this study may be the basis for further functional studies to evaluate the role of somatostatin receptors sst1 to sst5 in the diabetic state.

  14. SST, presumably via SSTR3/MUPP1, regulates tight junction permeability in cultured keratinocytes

  15. The cigarettes smoking and H. pylori infection are independent factors leading to decreasing of the SSTR3 mRNA level in gastric mucosa of patients with functional dyspepsia.

  16. There was a positive correlation between the percentage of tumor reduction by octreotide-lar and SSTR3 expression.

  17. SSTR transcripts are expressed and functional in retroorbital fibroblasts. SSTR1 is expressed in Grave's disease and octreotide inhibits retroorbital cell growth, explaining the SRIH therapeutic effect.

  18. SSTRs 1-5 are heterogeneously expressed in gastroenteropancreatic endocrine tumors

  19. expression of somatostatin (SS) and SS receptor (SSR) subtype 1 (sst1), sst2A, and sst3 in normal human thymic tissue

  20. somatostatin receptor transcripts were found in lymphocytes both from Graves' ophthalmopathy retroorbital tissues and blood samples, with levels of expression of SST1, -2, and -4 mRNA higher than those of the SST3 and -5 transcripts

Mouse (Murine) Somatostatin Receptor 3 (SSTR3) interaction partners

  1. results implicate beta-arrestin in the modulation of Sstr3 ciliary localization and further suggest a role for beta-arrestin in the mediation of Sstr3 ciliary signaling.

  2. The expression and localization of the three receptors (SSTR3-SSTR5) in wild-type (WT), single-knockout (SSTR1 KO) and double-knockout SSTR1/SSTR2 (DKO) mice, are reported.

  3. Both Sstr3 (and SStr2) receptors are required for the anticonvulsant effects mediated by cortistatin-14.

  4. SSTR3 immunoreactivity increases in ApoD(-/-) mice in all major nuclei of hypothalamus, median eminence, and ependymal cells of third ventricle.

  5. Mchr1 and Sstr3 are expressed and colocalized within cilia in multiple mouse brain regions, and they form heteromers.

  6. this novel finding that Rab21 regulates SSTR3 trafficking suggests that Rab21 may play a role in trafficking of other GPCRs.

  7. somatostatin receptor 3 expression was restricted to the plasma membrane of cilia in insulin- and growth hormone-secreting cells of the mouse, differing from previously reported immunohistochemical localization in cell bodies

  8. Receptor coupling to adenylyl cyclase is disrupted upon Sstr3 C-tail deletions.

  9. From the data of this study shown that somatostatin receptor 3 is critical for object recognition memory.

  10. The effect of sst2 receptor knockout on sst3 receptor mRNA localization and binding sites throughout the brain has been determined.

  11. Brain somatostatin receptors 1,2,4 and 5 are up-regulated in somatostatin-deficient mice, and SSTR3 is down-regulated.

  12. Expression of SSTR3, SSTR4, and SSTR5 in mouse proximal tubules complements the expression of SSTR1 and SSTR2 in collecting ducts as seen in other species.

  13. a lack of ciliary localization of somatostatin receptor type 3 (Sstr3) and melanin-concentrating hormone receptor 1 (Mchr1) in neurons from mice lacking the Bbs2 or Bbs4 gene

蛋白简介Somatostatin Receptor 3 (SSTR3)


Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.

Gene names and symbols associated with Somatostatin Receptor 3 蛋白 (SSTR3)

  • somatostatin receptor 3 (SSTR3)
  • somatostatin receptor 3 (LOC100303654)
  • somatostatin receptor 3 (Sstr3)
  • Smstr-3 蛋白
  • Smstr3 蛋白
  • Smstr28 蛋白
  • SS-3-R 蛋白
  • SS3-R 蛋白
  • SS3R 蛋白
  • SSR-28 蛋白
  • sst3 蛋白
  • SSTR 蛋白

Protein level used designations for Somatostatin Receptor 3 蛋白 (SSTR3)

somatostatin receptor type 3 , somatostatin receptor 3 , SS-3-R , SS3-R , SS3R , SSR-28 , somatostatin receptor 28 , somatostatin receptor subtype 3

427907 Gallus gallus
696585 Macaca mulatta
741644 Pan troglodytes
100227283 Taeniopygia guttata
100303654 Papio anubis
100597646 Nomascus leucogenys
6753 Homo sapiens
20607 Mus musculus
171044 Rattus norvegicus
481272 Canis lupus familiaris
518585 Bos taurus
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