mediates transport of a wide range of organic anions including bile acids, estrogen conjugates, ouabain, and digoxin; may be involved in digoxin toxicity. 再加上，我们可以发和数多这个蛋白质的别的产品。
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Oatp1a4 plays a major role in the hepatic accumulation of cardiac glycosides in mice.
Oatp1a4 does not appear to mediate the hepatic uptake of bile acid, but plays an important male-predominant role in secondary bile acid metabolism.
Oatp1a4 is more highly expressed in females than in males. Null mice showed inhibited hepatocyte transporter functions and an altered urinary metabolome.
Results show that Oatp1a4 can mediate the brain-to-blood and blood-to-brain transport of its substrate drugs across the blood-brain barrier.
Report critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp1a4 uptake transporter in mouse liver.
mediates transport of a wide range of organic anions including bile acids, estrogen conjugates, ouabain, and digoxin; may be involved in digoxin toxicity
solute carrier organic anion transporter family, member 1a4
, organic anion transporting polypeptide 2
, solute carrier family 21 (organic anion transporter), member 5