蛋白简介

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Gene names and symbols associated with sTNF-R2

• TNF receptor superfamily member 1B (TNFRSF1B) 抗体
• tumor necrosis factor receptor superfamily, member 1b (Tnfrsf1b) 抗体
• TNF receptor superfamily member 1B (Tnfrsf1b) 抗体

• CD120b 抗体
• p75 抗体
• p75TNFR 抗体
• TBPII 抗体
• TNF-alphaR2 抗体
• 显示所有的同义词和别名
• TNF-R-II 抗体
• TNF-R2 抗体
• TNF-R75 抗体
• TNFalpha-R2 抗体
• TNFBR 抗体
• Tnfr-1 抗体
• TNFR1B 抗体
• Tnfr2 抗体
• TNFR80 抗体
• TNFRII 抗体

Protein level used designations for sTNF-R2

TNF-R2 , TNF-RII , p75 TNF receptor , p80 TNF-alpha receptor , soluble TNFR1B variant 1 , tumor necrosis factor beta receptor , tumor necrosis factor binding protein 2 , tumor necrosis factor receptor 2 , tumor necrosis factor receptor superfamily member 1B , tumor necrosis factor receptor type II , TNF receptor beta chain , TNFR-II , p75 TNFR , p75