Signaling Lymphocytic Activation Molecule Family Member 1 蛋白 (SLAMF1)

High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. 再加上,我们可以发SLAMF1 抗体 (319)SLAMF1 试剂盒 (10)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
SLAMF1 27218 Q9QUM4
SLAMF1 6504 Q13291
SLAMF1 498286  
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Showing 10 out of 24 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
人细胞 His tag 100 μg Log in to see 20至21个工作日
$382.80
详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
$5,355.45
详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
详细
人细胞 大鼠 His tag 100 μg Log in to see 20至21个工作日
$382.80
详细
大肠杆菌(E. Coli) His tag,T7 tag 100 μg Log in to see 15至18个工作日
$672.00
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Mammalian Cells His tag   50 μg Log in to see 4 Days
$269.50
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Baculovirus infected Insect Cells His tag 50 μg Log in to see 13至16个工作日
$400.00
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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大肠杆菌(E. Coli) His tag 20 μg Log in to see 15至19个工作日
$400.00
详细
酵母菌 His tag   1 mg Log in to see 60至71个工作日
$2,520.83
详细

SLAMF1 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine) , ,
,
Human , , , , , , ,
, , , ,
Rat (Rattus) ,
, ,

更多Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1)互动伙伴

Mouse (Murine) Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) interaction partners

  1. the Slam locus has an overall inhibitory role during NK cell activation that is solely dependent on 2B4 (显示 CD244 蛋白). This effect is influenced by cytokines and leads to suppression of LFA-1 (显示 ITGAL 蛋白) activity.

  2. CRISPR-Mediated Slamf1Delta/Delta Slamf5Delta/Delta Slamf6Delta/Delta Triple Gene Disruption Reveals NKT (显示 CTSL1 蛋白) Cell Defects but Not T Follicular Helper Cell Defects.

  3. We demonstrated that Bacille Calmette-Guerin infection significantly upregulated SLAMF1, which enhanced inflammatory response by activating the NF-kappaB (显示 NFKB1 蛋白) signaling pathway and facilitated bacterial clearance in BCG (显示 SLC11A1 蛋白)-infected RAW264.7 cells and mice.

  4. Slamf1 and Slamf8 (显示 SLAMF8 蛋白) govern ROS (显示 ROS1 蛋白)-dependent innate immune responses of myeloid cells.

  5. The combined effects of RIIB deletion and pathogenic SLAM can lead to severe lupus nephritis in the B6 genetic background.

  6. SLAM-SAP (显示 APCS 蛋白) signaling promotes differentiation of IL-17 (显示 IL17A 蛋白)-producing T cells and progression of experimental autoimmune encephalomyelitis.

  7. The goal of the current study was to determine whether Slam haplotype affected NKT (显示 CTSL1 蛋白) and Vgamma4+ T-cell responses subsequent to coxsackievirus b3 infection.

  8. Signaling lymphocyte activation molecule regulates development of colitis in mice.

  9. Slamf1, which controls phagosomal/lysosomal fusion and phagosomal NADPH-oxidase (显示 NOX1 蛋白) activity, is required for T.cruzi replication in macrophages and dendritic cells, but not in other cells, which do not express the receptor.

  10. conclude that Slamf1 recruits a subset of Vps34 (显示 PIK3C3 蛋白)-associated proteins, which is involved in membrane fusion and NOX2 (显示 CYBB 蛋白) regulation

Human Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) interaction partners

  1. CD150 and CD180 (显示 CD180 蛋白) receptors may modulate transcriptional program in lymphocytic leukemia cells by regulating the transcription factor expression levels

  2. this paper shows that the X-linked lymphoproliferative disease gene product SAP (显示 APCS 蛋白) regulates signals induced through the co-receptor SLAM

  3. combination of signals via CD150 and CD180 (显示 CD180 蛋白) leads to blocking of pro-survival pathways that may be a restraining factor for neoplastic CLL B cells propagation in more than 50% of CLL cases where these receptors are coexpressed

  4. EBF1 (显示 EBF1 蛋白) is critical for transcriptional control of SLAMF1 gene in human B cells.

  5. MeV can hijack SLAMF1 to drive endocytosis using a complex pathway that shares features with canonical viral macropinocytosis, phagocytosis, and mechanotransduction. This uptake pathway is specific to SLAMF1-positive cells and occurs within 60 min of viral attachment.

  6. Malignant B-cell lines at the different stages of maturation only partially resemble their normal counterparts by CD150 expression. In malignant B-cell lines, CD150 expression on mRNA level is much broader than on protein level. CD150 isoforms are differentially expressed in normal and malignant B cells with predominant expression of mCD150 isoform.

  7. Data suggest that SLAMF1 is another significant piece in the intricate defective immune-regulatory function of patients with SLE.

  8. results indicate that loss of SLAMF1 expression in chronic lymphocytic leukemia modulates genetic pathways

  9. Upstream open reading frames regulate translation of the long isoform of SLAMF1 mRNA that encodes costimulatory receptor CD150

  10. Molecular dynamics analysis revealed that mutant R32Q and T53I structures of SAP (显示 APCS 蛋白) exhibited structural variation with respect to their backbone atoms before and after binding with the unphosphorylated SLAM peptide.

蛋白简介SLAMF1

蛋白简介

High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

Gene names and symbols associated with SLAMF1

  • signaling lymphocytic activation molecule family member 1 (SLAMF1)
  • signaling lymphocytic activation molecule family member 1 (Slamf1)
  • 4933415F16 蛋白
  • AA177906 蛋白
  • CD150 蛋白
  • CDw150 蛋白
  • ESTM51 蛋白
  • IPO-3 蛋白
  • RGD1560634 蛋白
  • Slam 蛋白
  • SLAMF1 蛋白

Protein level used designations for SLAMF1

signaling lymphocyte activation molecule , signaling lymphocytic activation molecule , signaling lymphocytic activation molecule family member 1 , IPO-3

GENE ID SPECIES
678672 Ovis aries
100351513 Oryctolagus cuniculus
425300 Gallus gallus
457436 Pan troglodytes
100597501 Nomascus leucogenys
27218 Mus musculus
6504 Homo sapiens
498286 Rattus norvegicus
403642 Canis lupus familiaris
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