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SIGLEC12 蛋白

(Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

recommended

SIGLEC12 Protein (AA 1-595) (GST tag) (ABIN1319985)

SIGLEC12 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

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recommended

SIGLEC12 Protein (His tag) (ABIN7579501)

SIGLEC12 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant WB, SDS, ELISA

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recommended

SIGLEC12 Protein (AA 27-141) (His tag) (ABIN7400804)

SIGLEC12 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, Imm, PC

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SIGLEC12 蛋白 by Origin

Find SIGLEC12 蛋白 for a variety of species such as anti-Human SIGLEC12, anti-Mouse SIGLEC12, anti-Chimpanzee SIGLEC12. The species listed below are among those available. Click on a link to go to the corresponding products.

SIGLEC12 蛋白 by Source

Here you will find SIGLEC12 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SIGLEC12 蛋白 by 蛋白类型

Here you can find SIGLEC12 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

SIGLEC12 蛋白 by 应用范围

Find SIGLEC12 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SIGLEC12 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

SIGLEC12 Protein (AA 1-595) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1319985

Quantity 10 μg

Datasheet Datasheet

SIGLEC12 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7579501

Quantity 100 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 27-141) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7400804

Quantity 100 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 317-512) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7404062

Quantity 100 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 22-218) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7403318

Quantity 100 μg

Datasheet Datasheet

SIGLEC12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2732049

Quantity 20 μg

Datasheet Datasheet

SIGLEC12 蛋白

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3011643

Quantity 100 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 21-483) (His tag)

Reactivity Chimpanzee

Source Yeast

Validations

Cat. No. ABIN1641406

Quantity 1 mg

Datasheet Datasheet

Aliases for SIGLEC12 蛋白

sialic acid binding Ig like lectin 12 (gene/pseudogene) (SIGLEC12) 蛋白
sialic acid binding Ig like lectin 12 (SIGLEC12) 蛋白
sialic acid binding Ig-like lectin 12 (SIGLEC12) 蛋白
S2V 蛋白
Siglec-XII 蛋白
SIGLECL1 蛋白
SLG 蛋白

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SIGLEC12 蛋白 by Origin

SIGLEC12 蛋白 by Source

SIGLEC12 蛋白 by 蛋白类型

SIGLEC12 蛋白 by 应用范围

Popular SIGLEC12 蛋白

Aliases for SIGLEC12 蛋白

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