anti-Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C (SEMA3C) 抗体

Binds to plexin family members and plays an important role in the regulation of developmental processes. 再加上,我们可以发SEMA3C 试剂盒 (11)SEMA3C 蛋白 (9)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SEMA3C 10512 Q99985
SEMA3C 20348 Q62181
SEMA3C 296787  
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Showing 10 out of 52 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 ELISA, IHC, WB Western blot analysis SEMA3C using Jurkat whole cell lysates ABIN6278525 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11至12个工作日
非结合性 ELISA, WB   100 μg 4至6个工作日
非结合性 ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μL 15至18个工作日
非结合性 WB Western blot analysis of SEMA3C Antibody in mouse lung tissue lysates (35ug/lane) 400 μL 2至3个工作日
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin mouse intestine tissue labeled withAnti-Sema3C/Semaphorin 3c Polyclonal Antibody, Unconjugated (ABIN720026) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL 3至7个工作日
非结合性 ELISA, IHC   100 μL Available
非结合性 IHC, ELISA   100 μg 2至3个工作日
小鼠 非结合性 WB Western blot analysis of extracts of various cell lines, using SEMA3C antibody. 200 μL 12至14个工作日
非结合性 WB   100 μL 11至14个工作日
非结合性 IHC, IHC (p)   100 μL 11至14个工作日


Human Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C (SEMA3C) interaction partners

  1. In the absence of neuropilins, plexin-A4 formed complexes with plexin-D1, and was required in addition to plexin-D1 to enable Sema3C-induced signal transduction.

  2. we show that SEMA3C promotes migration and invasion in vitro and cell dissemination in vivo.

  3. Study provide the first evidence that SEMA3C, SEMA5A and SEMA6D can be considered as markers of liver injury in chronic hepatitis C. While serum concentrations of SEMA3C and SEMA6D significantly increased with fibrosis stage in both HCV-g1 and HCV-g3 infections, the concentration of SEMA5A inversely correlated with fibrosis stage in both HCV genotypes.

  4. in situ hybridization analysis revealed that Sema 3C and Sema 3F are expressed at the RNA level in the endometriosis affected peritoneum

  5. Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner in prostate tumor cells.

  6. The exploratory genome-wide association studies confirmed APOE and identified the novel loci: rs2525776 near SEMA3C (P = 1 x 10(-8), OR = 3.3 [2.1-5.1]).

  7. Aberrant expression of sema3c is correlated with poor prognosis of pancreatic ductal adenocarcinoma patients and promotes tumor growth and metastasis by activating ERK1/2 signaling pathway.

  8. FR-sema3C could perhaps be used for the treatment of AMD.

  9. SEMA3C plays a role in the progression of breast cancer and may positively influence breast cancer cell adhesion, invasion and proliferation, as well as being associated with grade of disease and estrogen receptor status.

  10. Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.

  11. Increased levels of Sema3C protein may be associated with the progression of glioma tumor and have potential as a prognostic marker for outcome of glioma patients.

  12. SEMA3C expression increased in the transition from normal to malignant breast lesions and correlated with microvessel density and tumour grade and is differentially regulated in the development of breast versus oral neoplasia.

  13. Glioma stem cells preferentially secrete Sema3C and coordinately express PlexinA2/D1 receptors to activate Rac1/nuclear factor (NF)-kB signaling.

  14. p65-Sema3C, but not FR-sema3C, rendered A549 lung cancer cells resistant to serum deprivation, suggesting that previously reported protumorigenic activities of sema3C may be due to p65-Sema3C produced by tumor cells

  15. Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.

  16. SEMA3C is a novel adipokine regulated by weight changes.

  17. Capillary-like tubular formation was reduced by the addition of culture media of sema3C miRNA cells.

  18. The role of the motoneuronal Sema3 code could be to set population-specific axon sensitivity to limb-derived chemotropic Sema3 proteins, therefore specifying stereotyped motor nerve trajectories in their target field.

  19. cleavage of semaphorin 3C induced by ADAMTS1 promotes the migration of breast cancer cells, indicating that the co-expression of these molecules in tumors may contribute to the metastatic program

  20. correlation of gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients

Mouse (Murine) Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C (SEMA3C) interaction partners

  1. Post-crossing CCAs switch off their response to axon guidance cues, among which the secreted Semaphorin-3C (Sema3C), that act as attractants for pre-crossing axons on their way to the midline. This change is concomitant with an upregulation of the surface protein Ephrin-B1, which acts in CCAs to inhibit Sema3C signaling via interaction with the Neuropilin-1 (Nrp1) receptor.

  2. Taken together, epithelium-expressed SEMA3C plays a role in corneal epithelial wound closure and sensory nerve regeneration.

  3. Sema3c is a candidate that mediates interaction between cardiac neural crest cells and the second heart field during development of the outflow tract.

  4. analyzed a complementary set of ligand-specific and tissue-specific mutants to show that neural crest-derived SEMA3C activates NRP1 in the cardiac outflow tract endothelium

  5. Sema3A overrides the effects of Sema3C in cortical axons exposed to defined mixtures of these opposing guidance cues in vitro

  6. No changes were observed in the binding of Sema3C to Nrp1-silenced B16(F10) cells, nor in its chemorepellent activity.

  7. Data suggest that the formation and synaptic specificity of the GABAergic septohippocampal pathway relies on robust molecular mechanisms, independent of semaphorin 3C.

  8. the guidance factor Semaphorin 3C, which is expressed by corpus callosum neurons, acts through the neuropilin 1 receptor to orient axons crossing through the corpus callosum.

  9. Secreted sema3C favors cell survival and neuritogenesis of cultured cerebellar granule neurons

  10. GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis

  11. sema 3C promotes glomerular endothelial cell proliferation, adhesion, directional migration, and tube formation in vitro by stimulating integrin phosphorylation and VEGF120 secretion

  12. Taken together, our results reveal a molecular interaction between MMPs and semaphorins providing new insight into the molecular mechanism allowing axonal growth cone to respond to environmental guidance cues in the context of cortical development.

  13. Npn1-dependent morphogenesis is mediated by Sema3A and Sema3C in an additive manner.

  14. The endocytic pathway of neuropilin(Nrp)1 depends on its ligand: sema3C induces lipid raft-dependent endocytosis.

  15. mutations in GATA6 are genetic causes of congenital heart diseases involving outflow tract defects, as a result of the disruption of the direct regulation of semaphorin 3C-plexin A2 signaling

SEMA3C 抗原简介


Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).

Gene names and symbols associated with SEMA3C

  • semaphorin 3C (SEMA3C) 抗体
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (Sema3c) 抗体
  • semaphorin 3C (Sema3c) 抗体
  • 1110036B02Rik 抗体
  • Semae 抗体
  • SemE 抗体

Protein level used designations for SEMA3C

sema E , semaphorin E , semaphorin-3C , semaphorin-E , COLL-3 , collapsin-3

100054706 Equus caballus
10512 Homo sapiens
20348 Mus musculus
374090 Gallus gallus
512660 Bos taurus
296787 Rattus norvegicus
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