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The protein encoded by SMAD9 is a member of the SMAD family, which transduces signals from TGF-beta family members. 再加上，我们可以发SMAD9 抗体 (89) 和 SMAD9 试剂盒 (10)和数多这个蛋白质的别的产品。
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Differential expression of TGF-beta (显示 TGFB1 蛋白) superfamily members and role of Smad1 (显示 GARS 蛋白)/5/9-signalling in chondral versus endochondral chondrocyte differentiation.
Mutations in SMAD9 gene encoding for transforming growth factor (TGF)-[beta] superfamily have been identified in Pulmonary Arterial Hypertension.
Phosphorylated Smad1/5/8/9 specifically bound to the BREs of Smad8/9 gene. The present study reveals that Smad8/9 is a unique R-Smad regulated through the BMP pathway at the mRNA level.
Case Report: hamartomatous olyposis and gastrointestinal ganglioneuromas with SMAD9 germline mutation that reduces PTEN expression.
a detailed computational model for TGF-beta (显示 TGFB1 蛋白) signalling that incorporates elements of previous models together with crosstalking between Smad1 (显示 GARS 蛋白)/5/8 and Smad2 (显示 SMAD2 蛋白)/3 channels through a negative feedback loop dependent on Smad7 (显示 SMAD7 蛋白).
ATP production by NaF (显示 IL8 蛋白) promotes hypertrophy-like changes via activation of phospho-Smad8
TNF (显示 TNF 蛋白) activated NF-kappaB (显示 NFKB1 蛋白) pathway and inhibited the phosphorylation of Smad 1 (显示 GARS 蛋白)/5/8 and BMP-2 (显示 BMP2 蛋白)-induced osteoblastic differentiation in BMMSCs
CREBZF (显示 CREBZF 蛋白), a novel Smad8-binding protein.
Data suggest that Smads 1, 5 and 8 as potential prognostic markers and therapeutic targets for mTOR (显示 FRAP1 蛋白) inhibition therapy of prostate cancer.
Endoglin (显示 ENG 蛋白) promotes transforming growth factor beta-mediated Smad 1 (显示 GARS 蛋白)/5/8 signaling and inhibits endothelial cell migration through its association with GIPC (显示 GIPC1 蛋白)
Sphingosine 1 phosphate also up-regulated runt-related transcription factor 2 (Runx2 (显示 RUNX2 蛋白)) expression through S1PR2 (显示 S1PR2 蛋白)/RhoA (显示 RHOA 蛋白)/ROCK/Smad1 (显示 SMAD1 蛋白)/5/8 signaling.
BetA can enhance in vivo osteogenic potentials of BMP2 (显示 BMP2 蛋白), possibly via stimulating Smad 1 (显示 SMAD1 蛋白)/5/8 and p38 (显示 CRK 蛋白) pathways, and combination of both agents can be considered as a therapeutic strategy for bone diseases.
findings suggest that Smad9 is a new type of transcriptional regulator in BMP signaling.
The findings demonstrate for the first time that KMUP-1 can promote osteoblast maturation and differentiation in vitro via BMP-2 (显示 BMP2 蛋白)/Smad1 (显示 SMAD1 蛋白)/5/8 and Wnt (显示 WNT2 蛋白)/beta-catenin (显示 CTNNB1 蛋白) pathways.
Data indicate that PDGF (显示 PDGFA 蛋白)-AA promotes mesenchymal stem cel migration via bone morphogenetic protein 2 (BMP2 (显示 BMP2 蛋白))-smad (显示 SMAD1 蛋白) proteins smad1 (显示 SMAD1 蛋白)/5/8 activation requires lysosome-mediated degradation of PDGF (显示 PDGFA 蛋白) alpha Receptor (PDGFRalpha).
our data suggest a pivotal role for canonical BMP signaling demonstrating distinguished nonoverlapping function of pSmad8 with pSmad1 and pSmad5 in hfSCs regulation and hair morphogenesis but a redundant role in adult hair progenitors differentiation.
Data show that HtrA1 (显示 HTRA1 蛋白) is produced during osteoclastogenesis, and negatively regulates osteoblast differentiation, osteoblast differentiation and BMP2 (显示 BMP2 蛋白)-induced Smad1 (显示 SMAD1 蛋白)/5/8, ERK1/2 and p38 (显示 CRK 蛋白) phosphorylation in pre-osteoblasts.
FGF2 (显示 FGF2 蛋白) inhibited BMP9 (显示 GDF2 蛋白)-induced osteogenic differentiation by blocking BMP9 (显示 GDF2 蛋白)-induced Smads signaling and subsequently reducing Smads dependent up-regulation of ALK1 (显示 ACVRL1 蛋白) and ALK2 (显示 ACRV1 蛋白) in mesenchymal stem cells.
a detailed computational model for TGF-beta (显示 TGFB1 蛋白) signalling that incorporates elements of previous models together with crosstalking between Smad1 (显示 SMAD1 蛋白)/5/8 and Smad2 (显示 SMAD2 蛋白)/3 channels through a negative feedback loop dependent on Smad7 (显示 SMAD7 蛋白).
The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.
MAD, mothers against decapentaplegic homolog 9
, Mothers against decapentaplegic-like protein 9
, mothers against decapentaplegic homolog 9
, SMAD family member 9
, mothers against decapentaplegic homolog 9-like
, MAD homolog 9
, Mothers against decapentaplegic, drosophila, homolog of, 9
, SMAD, mothers against DPP homolog 9
, mothers against DPP homolog 9
, SMAD 9
, SMAD, mothers against DPP 8
, TGF-beta signal transducer Smad8