SETD8 蛋白
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins.
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-393) protein (His tag) Protein
SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-349) protein (His tag) Protein
SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) protein (His tag) Protein
SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) protein (GST tag) Protein
SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 195-352) 蛋白 Protein
SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 195-352) protein (His tag) Protein
SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) protein (GST tag) Protein
SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-336) protein (His tag) Protein
SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-352) protein (His tag) Protein
SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-429) protein (His tag) Protein
蛋白简介SETD8
蛋白简介
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).
Gene names and symbols associated with SETD8
- lysine methyltransferase 5A (KMT5A) 抗体
- lysine methyltransferase 5A (Kmt5a) 抗体
- lysine methyltransferase 5Ab (kmt5ab) 抗体
- lysine methyltransferase 5A S homeolog (kmt5a.S) 抗体
- 2410195B05Rik 抗体
- AA617402 抗体
- AW536475 抗体
- kmt5a 抗体
- kmt5a-a 抗体
- Pr-set7 抗体
- RGD1305893 抗体
- SET07 抗体
- SET8 抗体
- setd8 抗体
- setd8-a 抗体
- setd8b 抗体
- wu:fc23f12 抗体
- zgc:171649 抗体
Protein level used designations for SETD8
H4-K20-HMTase SETD8 , H4-K20-specific histone methyltransferase , H4K20-specific histone methyltransferase splice variant Set8b , N-lysine methyltransferase SETD8 , PR/SET domain containing protein 8 , PR/SET domain-containing protein 07 , PR/SET07 , SET domain-containing protein 8 , histone-lysine N-methyltransferase SETD8 , lysine N-methyltransferase 5A , PR-Set7 , SET domain-containing 8 , SET domain containing (lysine methyltransferase) 8b , SET domain containing 8b , N-lysine methyltransferase KMT5A , SET domain containing (lysine methyltransferase) 8 , histone methyltransferase Pr-set7/Set8 , lysine (K)-specific methyltransferase 5A , Histone-lysine N-methyltransferase KMT5A-A , Lysine-specific methylase 5A-A , N-lysine methyltransferase KMT5A-A , N-lysine methyltransferase SETD8-A , SET domain-containing protein 8-A , histone-lysine N-methyltransferase KMT5A-A , histone-lysine N-methyltransferase SETD8-A , lysine (K)-specific methyltransferase 5A S homeolog , lysine-specific methylase 5A-A
GENE ID | SPECIES |
---|---|
387893 | Homo sapiens |
67956 | Mus musculus |
532622 | Bos taurus |
100004770 | Danio rerio |
689820 | Rattus norvegicus |
100158384 | Xenopus laevis |
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