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SETD8 蛋白

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins.

10 results:

SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-393) protein (His tag) Protein

SETD8 宿主: 人 资源: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
产品编号 ABIN3093468
$7,594.15
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping 发货至: 美国
50个工作日
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-349) protein (His tag) Protein

SETD8 宿主: 小鼠 资源: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
产品编号 ABIN3134954
$7,594.15
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping 发货至: 美国
50个工作日
open_in_new 详细
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) protein (His tag) Protein

SETD8 宿主: 人 资源: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
产品编号 ABIN2731881
$302.50
Plus shipping costs $45.00 and $24.00 dry ice
50 μg
local_shipping 发货至: 美国
11个工作日
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 195-352) 蛋白 Protein

SETD8 宿主: 人 资源: 大肠杆菌（E. Coli） Recombinant > 98 % as determined by SDS-PAGE SDS
产品编号 ABIN2004726
$506.74
加上运输费 $45.00
100 μg (More quantities available)
local_shipping 发货至: 美国
11至13个工作日
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) protein (GST tag) Protein

SETD8 宿主: 人 资源: Baculovirus infected Insect Cells, Insect cells (Sf9) WB
产品编号 ABIN6700509
$289.00
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping 发货至: 美国
1至2个工作日
open_in_new 详细
open_in_new 详细

SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 195-352) protein (His tag) Protein

SETD8 宿主: 人 资源: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN5855179
$553.85
加上运输费 $45.00
50 μg (More quantities available)
local_shipping 发货至: 美国
13至16个工作日
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) protein (GST tag) Protein

SETD8 宿主: 人 资源: Baculovirus infected Insect Cells, Insect cells (Sf9) WB
产品编号 ABIN6700508
$562.00
Plus shipping costs $45.00 and $24.00 dry ice
50 μg
local_shipping 发货至: 美国
1至2个工作日
open_in_new 详细
open_in_new 详细

SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-336) protein (His tag) Protein

SETD8 宿主: Xenopus tropicalis 资源: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1618348
$2,907.67
加上运输费 $45.00
1 mg
local_shipping 发货至: 美国
57至68个工作日
open_in_new 详细
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-352) protein (His tag) Protein

SETD8 宿主: Cow 资源: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1623210
$2,959.00
加上运输费 $45.00
1 mg
local_shipping 发货至: 美国
57至68个工作日
open_in_new 详细
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-429) protein (His tag) Protein

SETD8 宿主: Schizosaccharomyces pombe 资源: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1591430
$3,197.33
加上运输费 $45.00
1 mg
local_shipping 发货至: 美国
57至68个工作日
open_in_new 详细
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  • 类型 Protein
    • Protein
  • 抗原 SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
    • SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Growth Hormone 1 (GH1)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • CD40 Ligand (CD40LG)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Interleukin 33 (IL33)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Adiponectin (ADIPOQ)
    • Ferrochelatase, HEMH (HEMH)
  • 应用范围
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Crystallization (Crys)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
  • 适用
    • 人
    • Cow
    • 小鼠
    • Schizosaccharomyces pombe
    • Xenopus tropicalis
  • 图像
  • 抗体来源
    • Baculovirus infected Insect Cells
    • 酵母菌
    • 大肠杆菌（E. Coli）
    • Insect Cells
    • Insect cells (Sf9)
  • 抗原表位
    • AA 195-352
    • AA 1-336
    • AA 1-349
    • AA 1-352
    • AA 1-393
    • AA 1-429
  • 标记
    • 非结合性
    • His tag
    • GST tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized

蛋白简介SETD8

蛋白简介

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).

Gene names and symbols associated with SETD8

  • lysine methyltransferase 5A (KMT5A) 抗体
  • lysine methyltransferase 5A (Kmt5a) 抗体
  • lysine methyltransferase 5Ab (kmt5ab) 抗体
  • lysine methyltransferase 5A S homeolog (kmt5a.S) 抗体
  • 2410195B05Rik 抗体
  • AA617402 抗体
  • AW536475 抗体
  • kmt5a 抗体
  • kmt5a-a 抗体
  • Pr-set7 抗体
  • RGD1305893 抗体
  • SET07 抗体
  • SET8 抗体
  • setd8 抗体
  • setd8-a 抗体
  • setd8b 抗体
  • wu:fc23f12 抗体
  • zgc:171649 抗体

Protein level used designations for SETD8

H4-K20-HMTase SETD8 , H4-K20-specific histone methyltransferase , H4K20-specific histone methyltransferase splice variant Set8b , N-lysine methyltransferase SETD8 , PR/SET domain containing protein 8 , PR/SET domain-containing protein 07 , PR/SET07 , SET domain-containing protein 8 , histone-lysine N-methyltransferase SETD8 , lysine N-methyltransferase 5A , PR-Set7 , SET domain-containing 8 , SET domain containing (lysine methyltransferase) 8b , SET domain containing 8b , N-lysine methyltransferase KMT5A , SET domain containing (lysine methyltransferase) 8 , histone methyltransferase Pr-set7/Set8 , lysine (K)-specific methyltransferase 5A , Histone-lysine N-methyltransferase KMT5A-A , Lysine-specific methylase 5A-A , N-lysine methyltransferase KMT5A-A , N-lysine methyltransferase SETD8-A , SET domain-containing protein 8-A , histone-lysine N-methyltransferase KMT5A-A , histone-lysine N-methyltransferase SETD8-A , lysine (K)-specific methyltransferase 5A S homeolog , lysine-specific methylase 5A-A

GENE ID SPECIES
387893 Homo sapiens
67956 Mus musculus
532622 Bos taurus
100004770 Danio rerio
689820 Rattus norvegicus
100158384 Xenopus laevis

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