Runt-Related Transcription Factor 1 (RUNX1) ELISA试剂盒

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. 再加上,我们可以发RUNX1 抗体 (285)RUNX1 蛋白 (8)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
RUNX1 12394 Q03347
RUNX1 861 Q01196
RUNX1 50662 Q63046
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Mouse (Murine) Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. In vivo, in vitro and systems biology results show that Runx1 exerts a pro-neurogenic function in neural precursor cells in vitro, while in vivo data remained inconclusive.

  2. High RUNX1 expression is associated with lymphoma.

  3. Specific Runx1-bound enhancer elements critically modulate lineage-dependent expressions of PLZF.

  4. Study reveals a previously unrecognized synergism between ETV6 (显示 ETV6 ELISA试剂盒)/RUNX1 and BCL2 (显示 BCL2 ELISA试剂盒) impacting on malignant disease and autoimmunity.

  5. Data provide evidence that Runx1 plays a role in regulating the sphingolipid rheostat in normal development and that perturbation of this cell fate regulator contributes to Runx-driven lymphomagenesis.

  6. The findings suggest that the absence of uPA (显示 PLAU ELISA试剂盒) correlates with increased levels of Runx transcriptional regulators in a way that promotes inflammation-associated carcinogenesis.

  7. Flt3 and cooperating Flt3/Runx1 mutations cause hematopoietic stem cell depletion and myeloid progenitor expansion during adult but not fetal stages of murine development.

  8. RUNX1 is essential for the development of the granular convoluted tubules in the submandibular glands; RUNX1 could also be involved in the membrane trafficking of the AQP5 (显示 AQP5 ELISA试剂盒) protein of the acinar cells in the SMG (显示 SNRPG ELISA试剂盒) in order to allow for the proper secretion of saliva (显示 RAG1AP1 ELISA试剂盒)

  9. High RUNX1 expression is associated with skin squamous cell carcinoma.

  10. deficiency alters the expression of a crucial subset of TAL1 (显示 TAL1 ELISA试剂盒)- and NOTCH1 (显示 NOTCH1 ELISA试剂盒)-regulated genes, including the MYB (显示 MYB ELISA试剂盒) and MYC (显示 MYC ELISA试剂盒) oncogenes, respectively.

Human Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. ETV6 (显示 ETV6 ELISA试剂盒)/RUNX1 (+) ALL may be heterogeneous in terms of prognosis, and variables such as MRD at end ofremission induction or additional structural abnormalities of 12p could define a subset of patients who are likely to have poor outcome.

  2. High RUNX1 expression is associated with lymphoma.

  3. PLDN (显示 PLDN ELISA试剂盒) is a direct target of RUNX1 and its dysregulation is a mechanism for platelet dense granule deficiency associated with RUNX1 haplodeficiency

  4. The here presented transcriptomic subgroup-based approach unified the gene expression profiles of RUNX1-CBFA2T3 (显示 CBFA2T3 ELISA试剂盒) and RUNX1-RUNX1T1 (显示 RUNX1T1 ELISA试剂盒) acute myeloid leukemia (显示 BCL11A ELISA试剂盒).

  5. Platelet CD34 (显示 CD34 ELISA试剂盒) expression and alpha/delta-granule abnormalities in GFI1B (显示 GFI1B ELISA试剂盒)- and RUNX1-related familial bleeding disorders.

  6. We observed a strong correlation between EVI1 (显示 MECOM ELISA试剂盒) and alpha1, 6-fucosyltransferase (FUT8 (显示 FUT8 ELISA试剂盒)) in the chronic phase of the disease and both of them were found to be up-regulated with the progression of the disease.

  7. A novel function of RUNX1 and offer an explanation for the link between RUNX1 mutations and chemotherapy and radiation resistance. Moreover, these data suggest that pharmacologic modulation of RUNX1 might be an attractive new approach to treat hematologic malignancies.

  8. high EVI1 (显示 MECOM ELISA试剂盒) expression might predict high risk of relapse in AML patients undergoing myeloablative allo-HSCT in CR1 (显示 CR1 ELISA试剂盒).

  9. Hypermethylation of the CTNNA1 (显示 CTNNA1 ELISA试剂盒) promoter was associated with unfavorable karyotype, and possessed the higher frequency of coexisting with ASXL1 (显示 ASXL1 ELISA试剂盒) and RUNX1 mutations.

  10. Three siblings with germline causative RUNX1 variant, developed acute myelomonocytic leukemia and acquired variants within the JAK (显示 JAK3 ELISA试剂盒)-STAT (显示 STAT1 ELISA试剂盒) pathway, specifically targeting JAK2 (显示 JAK2 ELISA试剂盒) and SH2B3 (显示 SH2B3 ELISA试剂盒).

Zebrafish Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. Our data suggest that runx1 and cbfb are required at 2 different steps during early hematopoietic stem cell development

  2. We propose that cohesin and CTCF (显示 CTCF ELISA试剂盒) have distinct functions in the regulation of runx1 during zebrafish embryogenesis.

  3. Morpholino knockdown of Myef2 (显示 MYEF2 ELISA试剂盒) or Runx1 in zebrafish results in reduced numbers of hematopoietic stem cells, suggesting that these two factors also interact in vivo to regulate hematopoiesis.

  4. Runx1 is induced by high Pu.1 level and in turn transrepresses pu.1 expression, thus constituting a negative feedback loop that fashions a favorable Pu.1 level required for balanced fate commitment to neutrophils versus macrophages.

  5. hematopoietic stem cell numbers depended on activity of the transcription factor Runx1, on blood flow, and on proper development of the dorsal aorta

  6. in zebrafish adult HSCs can be formed without an intact runx1.

  7. Zebrafish embryos lacking Rad21 (显示 RAD21 ELISA试剂盒), or cohesin subunit Smc3 (显示 SMC3 ELISA试剂盒), fail to express runx3 (显示 RUNX3 ELISA试剂盒) and lose hematopoietic runx1 expression in early embryonic development.

Xenopus laevis Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus.

  2. ETV6-RUNX1 (TEL-AML1) fusion and hyperdiploidy (>50 chromosomes) are favorable genetic features in childhood acute lymphoblastic leukemia (ALL).

  3. reveal a shift in Runx2 (显示 RUNX2 ELISA试剂盒) function protein during vertebrate evolution towards its exclusive roles in cartilage hypertrophy and bone differentiation within the amniote lineage

RUNX1 抗原简介

Antigen Summary

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RUNX1

  • uncharacterized LOC473981 (LOC473981) 抗体
  • runt-related transcription factor (runt) 抗体
  • runt related transcription factor 1 (Runx1) 抗体
  • runt related transcription factor 1 (RUNX1) 抗体
  • runt-related transcription factor 1 (runx1) 抗体
  • runt related transcription factor 1 L homeolog (runx1.L) 抗体
  • runt-related transcription factor 1 (RUNX1) 抗体
  • runt-related transcription factor 1 (Runx1) 抗体
  • AI462102 抗体
  • aml 抗体
  • aml-1 抗体
  • Aml1 抗体
  • aml1-evi-1 抗体
  • amlcr1 抗体
  • cbfa2 抗体
  • evi-1 抗体
  • Pebp2a2 抗体
  • pebp2ab 抗体
  • Pebpa2b 抗体
  • Runx-1 抗体
  • runx1 抗体
  • runxa 抗体
  • XAML 抗体
  • Xaml1 抗体

Protein level used designations for RUNX1

runt-related transcription factor 1 , runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) , runt-related transcription factor , runt protein , CBF-alpha-2 , PEA2-alpha B , PEBP2-alpha B , SL3-3 enhancer factor 1 alpha B subunit , SL3/AKV core-binding factor alpha B subunit , acute myeloid leukemia 1 protein , core binding factor alpha 2 , core-binding factor subunit alpha-2 , oncogene AML-1 , polyomavirus enhancer-binding protein 2 alpha B subunit , runt domain, alpha subunit 2 , AML1-EVI-1 fusion protein , core-binding factor, runt domain, alpha subunit 2 , aml1 , runt-related transcription factor a , runx1a , Acute myeloid leukemia 1 protein , Core-binding factor subunit alpha-2 , aml1 oncogene , ch-runtB2 , acute myeloid leukemia 1 , factor, runt domain, alpha subunit 2 , core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene) , runt related transcription factor 1

GENE ID SPECIES
473981 Pan troglodytes
100302713 Saccoglossus kowalevskii
12394 Mus musculus
861 Homo sapiens
58126 Danio rerio
379657 Xenopus laevis
396152 Gallus gallus
487746 Canis lupus familiaris
529631 Bos taurus
50662 Rattus norvegicus
100512633 Sus scrofa
100724149 Cavia porcellus
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