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RPN2 encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. 再加上，我们可以发Ribophorin II 抗体 (59) 和 Ribophorin II 蛋白 (11)和数多这个蛋白质的别的产品。
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RPN13 binds ubiquitin with an affinity similar to that of other proteasome-associated ubiquitin receptors and that RPN2, ubiquitin, and the deubiquitylase UCH37 bind to RPN13 with independent energetics.
RPN2 (显示 PSMD1 ELISA试剂盒) expression correlates with gastric adenocarcinoma cell invasion and shows promise as a new prognostic factor in human gastric adenocarcinoma
Data suggest that RPN2 (显示 PSMD1 ELISA试剂盒) is involved in the regulation of lethal cancer phenotypes and represents a promising new target for RNAi-based medicine against non-small cell lung cancer.
Together, our findings suggest that the interaction of Psmd1 (显示 PSMD1 ELISA试剂盒) with Adrm1 (显示 Adrm1 ELISA试剂盒) is controlled by SUMOylation in a manner that may alter proteasome composition and function.
Of the total, the deregulation of several genes (CDK1 (显示 CDK1 ELISA试剂盒), CDK2 (显示 CDK2 ELISA试剂盒), CDK4 (显示 CDK4 ELISA试剂盒), MCM2 (显示 MCM2 ELISA试剂盒), MCM3 (显示 MCM3 ELISA试剂盒), MCM4 (显示 MCM4 ELISA试剂盒), EIF3a (显示 EIF6 ELISA试剂盒) and RPN2 (显示 PSMD1 ELISA试剂盒)) were potentially associated with disease development and progression.
these results indicated that high glycosylation of CD63 (显示 CD63 ELISA试剂盒) by RPN2 (显示 PSMD1 ELISA试剂盒) is implicated in clinical outcomes in breast cancer patients
Increased 26S proteasome non-ATPase regulatory subunit 1 (显示 PSMD1 ELISA试剂盒) in the aqueous humor of patients with age-related macular degeneration compared to control subjects.
Furthermore, our study reveals that high expression of RPN2 (显示 PSMD1 ELISA试剂盒) and concomitant accumulation of mtp53 were associated with cancer tissues in a small cohort of metastatic breast cancer patients.
The 26S proteasome (显示 Psmd4 ELISA试剂盒) plays a key role in promoting apoptosis induced by high doses of UV irradiation.
p38 MAPK (显示 MAPK14 ELISA试剂盒) negatively regulates the proteasome activity by phosphorylating Thr (显示 TRH ELISA试剂盒)-273 of Rpn2 (显示 PSMD1 ELISA试剂盒)
S-glutathionylation of Rpn2 is a contributory mechanism for H2O2-induced inhibition of 26 S proteasomal function
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
26S proteasome non-ATPase regulatory subunit 1
, 26S proteasome regulatory subunit RPN2
, 26S proteasome regulatory subunit S1
, 26S proteasome subunit p112
, dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit
, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
, oligosaccharyltransferase complex subunit (non-catalytic)
, ribophorin 2
, ribophorin II
, ribophorin ii
, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2-like
, ribophorin II S homeolog