anti-Rh Blood Group, D Antigen (RHD) 抗体

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. 再加上,我们可以发RHD 试剂盒 (8)RHD 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
RHD 6007 Q02161
RHD 19746 Q8CF94
RHD 60414 O88298
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
非结合性 WB WB Suggested Anti-RHD Antibody Titration: 1.0 ug/ml Positive Control: 293T Whole Cell RHD is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells 100 μL Log in to see 2至3个工作日
非结合性 WB Western blot analysis of CD240d expression in HeLa (A), NIH3T3 (B), mouse brain (C), rat brain (D) whole cell lysates. 200 μL Log in to see 13至14个工作日
非结合性 ELISA, WB Western Blot (WB) analysis of Mouse Brain cells using CD240d Polyclonal Antibody. 100 μL Log in to see Available
非结合性 WB 50 μg Log in to see 11至14个工作日
非结合性 WB 50 μg Log in to see 11至14个工作日
非结合性 WB RHD Antibody (Center)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RHD antibody detected the RHD protein (arrow). 400 μL Log in to see 10至11个工作日
非结合性 WB Western blot analysis in A549 cell line lysates (35ug/lane). 400 μL Log in to see 2至3个工作日
非结合性 ELISA, WB 200 μL Log in to see 12至14个工作日
小鼠 非结合性 FACS, IP   0.1 mg Log in to see 8至11个工作日

引用最多的anti-RHD 抗体

  1. Human Monoclonal RHD Primary Antibody for FACS, IP - ABIN260386 : Avent, Judson, Parsons, Mallinson, Anstee, Tanner, Evans, Hodges, Maciver, Holmes et al.: Monoclonal antibodies that recognize different membrane proteins that are deficient in Rhnull human erythrocytes. One group of antibodies reacts with a variety of cells and tissues whereas the other ... in The Biochemical journal 1988 (PubMed)


Human Rh Blood Group, D Antigen (RHD) interaction partners

  1. 4 novel RHD alleles, each characterized by a single nucleotide substitution were identified. RHD*67T, RHD*173T, and RHD*579C give rise to a weak D phenotypical expression. Their corresponding amino acid changes are predicted to be located in the membrane-spanning or intracellular domains of the RhD protein. RHD*482G is the 4th substitution.

  2. Extensive studies show that the RHD*1227A is the most prevalent DEL allele in East Asian populations and may have confounded the initial molecular studies.

  3. The most prevalent DEL allele was RHD*DEL1 (c.1227G>A), which is proven to be immunogenic. A high frequency of RHD*Psi was detected in the donors with nondeleted RHD alleles (31%), far superior to the frequency of RHD variant alleles (15.5%).

  4. Among the weak D phenotypes in Tunisia, no novel RHD allele was found and almost 90% were caused by alleles of the weak D Type 4 cluster, of which 88% represented the weak D Type 4.0 allele. Based on established RH haplotypes for variant RHD and RHCE alleles and the lack of adverse clinical reports, we recommend D+ transfusions for patients with weak D Type 4.0 in Tunisia.

  5. Absence of the whole RHD gene is common among RhD negative blood donors from Qingdao region, and there are rich genetic polymorphisms for this locus

  6. study 94.9% of the partial D samples revealed altered RHCE variant alleles and 5.7% of the samples with altered RHD allele predicted partial c, partial e and the lack of the high prevalence hr(B) and hr(S) antigens.

  7. The RHD 1227G>A mutation contributes to the molecular basis of Del phenotype in the Taiwanese population. The point mutation results in aberrant frame shift or exon deletion transcripts and generates D protein with weak antigen presenting function.

  8. In this mixed Brazilian population, the most frequent weak D types were 1, 4, 3 and 2 (frequencies of 4.35%, 2.32%, 1.46% and 0.29%, respectively; total of 8.41%) and partial D was found in 2.90% of samples carrying the RHD gene. For samples with inconclusive RhD typing, 53.33% of them presented weak and partial RHD, and 43.75% had concomitantly more than one RHD variant

  9. sequence comparisons revealed high sequence similarity between Patr_RHbeta and Hosa_RHCE, while the chimpanzee Rh gene closest to Hosa_RHD was not Patr_RHa but rather Patr_RHy

  10. Six weak D types in the Russian Federation: the most common type 3 (49.2%) and type 1 (28.6%), type 2 (14.3), type 15 (4.8%), type 4.2 (DAR) (1.6%) and type 6 (1.6%).

  11. The frequency of RhD negative homozygosity in the Cypriot population was estimated to be 7.2%, while the frequencies of RHD hemizygosity and RhD positive homozygosity was calculated to be 39.2 and 53.6%, respectively.

  12. Occurrence of partial RhD alleles in the Tunisian population.

  13. The RHCE gene intron 4 of Han Chinese, Tibetans, and Mongols differs from the RHD gene intron 4 in the presence of a 652-bp fragment.

  14. Reduced expression of D antigen is caused not only by missense mutation of the RHD gene, but also by silent mutation that may affect splicing.

  15. Loss of heterozygosity of RhD gene on chromosome 1p in acute myeloid leukemia.

  16. The data indicate that partial DEL women appear at risk of alloimmunization to the D antigen.

  17. Weak D type 4.0 appears to be the most prevalent weak D in our population. However, all samples must be sequenced in order to determine the exact subtype of weak D type 4, since weak D type 4.2 has considerable clinical importance

  18. Rh antibodies in SCD patients with RH variants can be clinically significant and, therefore, matching patients based on RH variants should be considered.

  19. Paternal RHD zygosity determination in Tunisians: evaluation of three molecular tests.

  20. Serologic findings of RhD alleles in Egyptians and their clinical implications.

RHD 抗原简介


The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RHD

  • Rh blood group D antigen (RHD) 抗体
  • Rh blood group, D antigen (Rhd) 抗体
  • CD240D 抗体
  • DIIIc 抗体
  • Rh 抗体
  • Rh4 抗体
  • RH30 抗体
  • Rhced 抗体
  • RhDCw 抗体
  • RHDel 抗体
  • RHDVA(TT) 抗体
  • RhII 抗体
  • RhK562-II 抗体
  • Rhl1 抗体
  • RhPI 抗体
  • RHPII 抗体
  • RHXIII 抗体

Protein level used designations for RHD

D antigen (DCS) , RH polypeptide 2 , Rh blood group antigen Evans , Rh blood group, D anitgen , Rhesus blood group D antigen allele DIII type 7 , Rhesus system D polypeptide , blood group Rh(D) polypeptide , rhesus D antigen , Rh-like polypeptide , Rhesus blood group CE and D , erythrocyte membrane glycoprotein Rh30

6007 Homo sapiens
19746 Mus musculus
60414 Rattus norvegicus
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