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RARRES1 was identified as a retinoid acid (RA) receptor-responsive gene. 再加上，我们可以发RARRES1 抗体 (61) 和 RARRES1 蛋白 (10)和数多这个蛋白质的别的产品。
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TIG1 interacted with DNAJC8 in the cytosol, and this interaction completely blocked DNAJC8-mediated PKM2 (显示 PKM ELISA试剂盒) translocation and inhibited glucose uptake. Furthermore, increased glycose uptake was observed in cells in which TIG1 was silenced.
Data demonstrated that RARRES1 expression is lost in choriocarcinoma tumors due to promotor hypermethylation. Also, further results hypothesized that RARRES1 might be a negative regulator of EMT (显示 ITK ELISA试剂盒) through induction of contact inhibition.
Data show that retinoic acid receptor (显示 RARA ELISA试剂盒) responder 1 (RARRES1) expression is subtype-dependent and regulated by DNA methylation and the expression of aldehyde dehydrogenase 1A3 (ALDH1A3 (显示 ALDH1A3 ELISA试剂盒)).
Data suggest that Retinoic Acid Receptor (显示 RARA ELISA试剂盒) Responder (RARRES1)/ Tazarotene-induced gene-1 (TIG-1) may serve as a target for therapeutic intervention both in cancer and in angiogenesis-related disorders.
Authors found that transmembrane protein 192 (TMEM192) interacted with TIG1. Authors also found that both TIG1A and TIG1B isoforms interacted and co-localized with TMEM192 in HtTA cervical cancer cells. The expression of TIG1 induced the expression of autophagy-related proteins.
All-trans retinoic acid modulated secretion of RARRES1 in a dose dependent manner.
our data suggested that epigenetic silencing of TIG1 gene expression by promoter hypermethylation may play an important role in hepatocellular carcinoma .
High TIG1 expression is associated with inflammatory breast cancer through activation of Axl (显示 AXL ELISA试剂盒) kinase.
Analysis of a standard liver fibrosis model (CCl(4 (显示 CCL4 ELISA试剂盒))) demonstrated an early induction of RARRES1 mRNA and protein expression.
genotype-associated hypermethylation of the ETS (显示 ETS1 ELISA试剂盒)-family target gene RARRES1 influences methylation at its neighbor gene LXN (显示 LXN ELISA试剂盒) and could be useful as a prognostic biomarker.
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.
tazarotene-induced protein 1
, retinoic acid receptor responder (tazarotene induced) 1
, retinoic acid receptor responder protein 1
, ovocalyxin 32
, RAR-responsive protein TIG1
, tazarotene-induced gene 1 protein
, 32 kDa eggshell matrix protein