anti-Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) 抗体

The product of P2RX3 belongs to the family of purinoceptors for ATP. 再加上,我们可以发Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
P2RX3 5024 P56373
P2RX3 81739 P49654
P2RX3 228139 Q3UR32
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Showing 10 out of 79 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Heart, antibody was diluted at 1:100. 100 μL Log in to see 16 Days
$181.73
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-P2RX3/ATP receptor Polyclonal Antibody, Unconjugated (ABIN705866) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rabbit bladder labeled with Anti-P2RX3/ATP receptor Polyclonal Antibody, Unconjugated (ABIN705866) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3至7个工作日
$306.90
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非结合性 ICC, FACS, IF, IHC (p), IP, IHC, WB Double immunofluorescence staining in cultured human bladder urothelial cells (BUCs). BUCs show cytokeratin (red areas) and P2X3 (green areas) expression Immunohistochemistry-Paraffin: P2X3/P2RX3 Antibody [ABIN250458] - DRG sections double-labeled for ASIC3 (red) and either P2X3 (green, A) or TRPV1 (green, B); double-labeled cells are yellow or orange 0.05 mL Log in to see 7至9个工作日
$373.75
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非结合性 IHC, IHC (p), WB Immunohistochemistry-Paraffin: P2X3 Antibody [NBP2-33848] - renal cancer Immunohistochemistry-Paraffin: P2X3 Antibody [NBP2-33848] - hippocampus 0.1 mL Log in to see 10至13个工作日
$491.63
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非结合性 IHC, IHC (p) Anti-P2RX3 / P2X3 antibody  ABIN1049196 IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-P2RX3 / P2X3 antibody  ABIN1049196 IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11至14个工作日
$484.00
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豚鼠 非结合性 IHC, IHC (fro), IHC (p), WB P2X3 is a subunit in the family of ion channels activated by extracellular ATP. It was cloned from rat dorsal root ganglia. P2X3 has two putative transmembrane domains with intracellular N- and C-termini. It can form homomeric channels and heteromeric channels with other members of the family. P2X3 is expressed in nociceptive sensory neurons. Immunocytochemistry/Immunofluorescence: P2X3/P2RX3 Antibody [ABIN250462] - Staining in rat DRG. 0.05 mL Log in to see 8至11个工作日
$415.44
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非结合性 WB P2RX3 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the P2RX3 antibody detected the P2RX3 protein (arrow). 400 μL Log in to see 10至11个工作日
$335.50
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大鼠 非结合性 WB Western blot analysis of extract of rat testis cells, using P2RX3 antibody. 100 μL Log in to see 16 Days
$334.77
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非结合性 ELISA, IHC (p), WB 200 μL Log in to see 12至14个工作日
$438.90
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Hamster 非结合性 ICC, IF, IHC, WB   50 μL Log in to see 11至14个工作日
$625.17
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引用最多的anti-Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 抗体

  1. Human Polyclonal P2RX3 Primary Antibody for IHC, IHC (fro) - ABIN250462 : Kaan, Yip, Patel, Davies, Marchand, Cockayne, Nunn, Dickenson, Ford, Zhong, Malcangio, McMahon: Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats. in Brain : a journal of neurology 2010 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal P2RX3 Primary Antibody for ICC, FACS - ABIN250458 : Tamburro, Fredolini, Espina, Douglas, Ranganathan, Ilag, Zhou, Russo, Espina, Muto, Petricoin, Liotta, Luchini: Multifunctional core-shell nanoparticles: discovery of previously invisible biomarkers. in Journal of the American Chemical Society 2011 (PubMed)
    Show all 3 Pubmed References

  3. Rat (Rattus) Polyclonal P2RX3 Primary Antibody for IF, IHC - ABIN238884 : Park, Bae, Kim, Jo, Kim, Jung, Kim, Oh: Substance P Sensitizes P2X3 in Nociceptive Trigeminal Neurons. in Journal of dental research 2010 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal P2RX3 Primary Antibody for IF, IHC - ABIN239021 : Xu, Chu, Brederson, Jarvis, McGaraughty: Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats. in Journal of neuroscience research 2012 (PubMed)

更多抗Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3的相互作用对抗体

Human Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) interaction partners

  1. Druggable negative allosteric site of P2X3 receptors.

  2. conclude that the inter-subunit salt bridge between E112 and R198 of the head and dorsal fin domains, respectively, serves to control the mobility of these domains during agonist-activation of the hP2X3R

  3. P2X3 expressions in endometriosis endometrium and endometriotic lesions were significantly higher as compared with control endometrium, and positively correlated with pain.

  4. P2X3 receptor expression was up-regulated in neurons from patients with temporal lobe epilepsy.

  5. X-ray crystal structures of the human P2X3 receptor in apo (显示 C9orf3 抗体)/resting, agonist-bound/open-pore, agonist-bound/closed-pore/desensitized and antagonist-bound/closed states

  6. there is a relationship between the elevated expression of P2X3 receptor and P2X7 receptor (显示 P2RX7 抗体) in peripheral blood leukocytes and high serum epinephrine and norepinephrine levels in hyperthyroidism patients.

  7. Data show that monoclonal antibodies directed against human P2X3 (12D4) potentiated the slow inactivating current mediated by the heteromeric purinergic receptor (显示 P2RX1 抗体) hP2X2/3 channel.

  8. Data indicate P2X3 purinergic receptors as potential new targets for hepatocellular carcinoma (HCC (显示 FAM126A 抗体)) therapy.

  9. Results demonstrate that the stoichiometry of the heterotrimeric hP2X2/3 receptor is not fixed, but determined by the relative availability of P2X2 (显示 P2RX2 抗体) and P2X3 subunits

  10. Urothelial P2X3 receptors decreased significantly in responders after Lipotoxin instillation, but not after BoNT-A injection.

Mouse (Murine) Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) interaction partners

  1. This study demonstrated that the P2X3-immunoreactive nerve endings in the rat tracheal mucosa have unique morphological characteristics, and these endings may be rapidly adapting receptors and/or irritant receptors that are activated by mucosal irritant stimuli.

  2. Data suggest that the negative inhibition of P2X3R activity by the BNP (显示 BNC2 抗体)/NPR-A (显示 NPR1 抗体) pathway results in a decreased P2X3R-mediated excitability of trigeminal neurons in wildetype cultures. In familial hemiplegic migraine type-1 model cultures, however, lack of efficient P2X3Rs downregulation contributes to the neuronal hyperexcitability phenotype.

  3. P2X3 receptors on mouse trigeminal ganglion neurons are subjected to contrasting modulation by inhibitory brain natriuretic peptide (显示 BNP 抗体) and facilitatory calcitonin gene-related peptide (显示 CALCA 抗体) that both operate via complex intracellular signaling.

  4. mouse trigeminal neurons endogenous BNP (显示 BNC2 抗体) acts on NPR-A (显示 NPR1 抗体) receptors to determine constitutive depression of P2X3 receptor function. Tonic inhibition of P2X3 receptor activity by BNP (显示 BNC2 抗体)/NPR-A (显示 NPR1 抗体)/PKG (显示 PRKG1 抗体) pathways occurs via two distinct mechanisms: P2X3 serine phosphorylation and receptor redistribution to non-raft membrane compartments

  5. This study observed maltodextrin and fat preference deficits in "taste-blind" P2X2 (显示 P2RX2 抗体)/P2X3 knockout mice.

  6. a slow modulatory action by BNP (显示 BNC2 抗体) on TRPV1 (显示 TRPV1 抗体) and P2X3 receptors outlining the role of this peptide as a negative regulator of trigeminal sensory neuron excitability to nociceptive stimuli

  7. P2X(3)R overexpression may underlie ectopic mechanical allodynia in the whisker pad skin

  8. genetic manipulation of TRPV1 (显示 TRPV1 抗体) and P2X3 leads to reduction in colorectal mechanosensation peripherally and compensatory changes and/or disinhibition of other channels centrally.

  9. up-regulation of P2X3 receptors probably is already maximal and is apparently contributed by basal CGRP (显示 CALCA 抗体) and BDNF (显示 BDNF 抗体) levels

  10. Structure and function of P2RX3 is reviewed, and its role in treatment of pain is discussed. [Review Article]

Zebrafish Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) interaction partners

Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) 抗原简介

蛋白简介

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Gene names and symbols associated with P2RX3

  • purinergic receptor P2X 3 (P2RX3) 抗体
  • purinergic receptor P2X 3 (P2rx3) 抗体
  • purinergic receptor P2X, ligand-gated ion channel, 3 (P2rx3) 抗体
  • purinergic receptor P2X, ligand-gated ion channel, 3a (p2rx3a) 抗体
  • 4930513E20Rik 抗体
  • fb99b08 抗体
  • p2rx3 抗体
  • p2x3 抗体
  • wu:fb99b08 抗体
  • zfP2X3 抗体
  • zP2X3 抗体

Protein level used designations for P2RX3

ATP receptor , P2X purinoceptor 3 , P2X receptor, subunit 3 , purinergic receptor P2X3 , purinoceptor P2X3 , P2X3 , purinergic receptor P2X, ligand-gated ion channel, 3 , P2X3 purinoceptor , zP2X3.1

GENE ID SPECIES
5024 Homo sapiens
81739 Rattus norvegicus
228139 Mus musculus
428856 Gallus gallus
448782 Canis lupus familiaris
530468 Bos taurus
742961 Pan troglodytes
58147 Danio rerio
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