PCSK9 抗体
(Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq, Jul 2008].
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PCSK9 抗体 by Grade
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PCSK9 抗体 by 适用
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PCSK9 抗体 by 克隆形成能力
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PCSK9 抗体 by 克隆
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PCSK9 抗体 by Fragment
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Quantity
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Cat. No.
ABIN7427117
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Cat. No.
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Cat. No.
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Quantity
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Application
WB, ELISA, IHC, FACS
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Cat. No.
ABIN3032342
Quantity
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Datasheet
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Cat. No.
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Cat. No.
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Application
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Validations
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Cat. No.
ABIN1176242
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
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- (1)
Cat. No.
ABIN761831
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7164836
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Latest Publications for our PCSK9 抗体
: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." in: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).: "Proprotein Convertase Subtilisin/Kexin Type 9 Is Associated with Degenerating Adipocytes in Abdominal Aortic Aneurysm." in: Journal of oleo science, Vol. 67, Issue 10, pp. 1355-1360, (2018) (PubMed).
: "Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 4627-35, (2016) (PubMed).
: "Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism." in: The Journal of biological chemistry, Vol. 292, Issue 4, pp. 1510-1523, (2016) (PubMed).
: "Modulation of cholesterol transport by insulin-treated gestational diabetes mellitus in human full-term placenta." in: Biology of reproduction, Vol. 88, Issue 1, pp. 16, (2013) (PubMed).
: "The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1." in: Molecular biology of the cell, Vol. 21, Issue 12, pp. 2087-96, (2010) (PubMed).
: "Expression of the hepatic Niemann-Pick C1 like 1 protein gene is sensitive to rosuvastatin treatment of primary human hepatocytes." in: Pharmacogenetics and genomics, Vol. 20, Issue 7, pp. 455-8, (2010) (PubMed).
: "Molecular basis for LDL receptor recognition by PCSK9." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 6, pp. 1820-5, (2008) (PubMed).
: "Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment." in: Clinical chemistry, Vol. 54, Issue 6, pp. 1038-45, (2008) (PubMed).
: "PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans." in: The FEBS journal, Vol. 275, Issue 13, pp. 3480-93, (2008) (PubMed).
Aliases for PCSK9 抗体
proprotein convertase subtilisin/kexin type 9 (PCSK9) 抗体proprotein convertase subtilisin/kexin type 9 L homeolog (pcsk9.L) 抗体
proprotein convertase subtilisin/kexin type 9 (pcsk9) 抗体
proprotein convertase subtilisin/kexin type 9 (Pcsk9) 抗体
AI415265 抗体
AI747682 抗体
FH3 抗体
HCHOLA3 抗体
LDLCQ1 抗体
NARC-1 抗体
NARC1 抗体
Narc1 抗体
PC9 抗体
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