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Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. 再加上，我们可以发PLAG1 蛋白 (4) 和 和数多这个蛋白质的别的产品。
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Human Monoclonal PLAG1 Primary Antibody for ELISA, WB - ABIN562260
Pallasch, Patz, Park, Hagist, Eggle, Claus, Debey-Pascher, Schulz, Frenzel, Claasen, Kutsch, Krause, Mayr, Rosenwald, Plass, Schultze, Hallek, Wendtner: miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia. in Blood 2009
PLAG1 is a microRNA target gene that is overexpressed in Wilms tumors with mutations in microRNA processing genes.
HRAS (显示 HRAS 抗体) mutations were more common in epithelial-myoepithelial carcinomas (EMCAs) with intact PLAG1 and HMGA2. Most EMCAs arose ex pleomorphic adenoma (PA)and the genetic profile of EMCA varies with the absence or presence of preexisting PA and its cytogenetic signature. Progression to higher grade EMCA with intact PLAG1 and HMGA2 correlates with the presence of TP53 (显示 TP53 抗体), FBXW7 (显示 FBXW7 抗体) mutations, or SMARCB1 (显示 SMARCB1 抗体) deletion.
Plag1 expression is lost in malignant transformation from pleomorphic adenoma to carcinoma ex pleomorphic adenoma.
MiR (显示 MLXIP 抗体)-26a can facilitate occurrence of pituitary tumor and invasiveness, probably via inhibiting PLAG1 expression.
expression of PLAG1 can be considered a valuable diagnostic marker for recurrent pleomorphic adenoma
High PLAG1 expression is associated with pleomorphic adenoma.
The sensitivity (55%) and specificity (75%) of PLAG1 in diagnosing PA in FNAs is relatively modest thus limiting its diagnostic utility.
The Thr34 of PLAG1 is critical for LpMab-10 recognition.
Data indicate that SLIT2 (显示 SLIT3 抗体), miR (显示 MLXIP 抗体)-218-1, RET (显示 RET 抗体)/PLAG1 and SLIT2 (显示 SLIT3 抗体)/ROBO1 (显示 ROBO1 抗体) pathway involved in Hirschsprung's disease.
Altogether, these data suggest that HMGA2 is an upstream activator of PLAG1.
Genome-Wide Association Study Reveals the PLAG1 Gene for Knuckle, Biceps and Shank (显示 SHANK2 抗体) Weight in Simmental Beef Cattle.
This study demonstrates a strong association of early life body weight with pleiomorphic adenoma gene 1 (PLAG1) genotype in Holstein-Friesian dairy calves. Peripubertal body weight and growth rate were also significantly associated with PLAG1 genotype.
Forced expression of PLAG1 under the control of the Pdx1 (显示 PDX1 抗体) or Ngn3 (显示 NEUROG3 抗体) promoter in murine pancreas induces different degrees of endocrine hormone imbalances.
Data indicate a plausible Plag1-Egr1 (显示 EGR1 抗体)-CD44 (显示 CD44 抗体) regulatory pathway in the T-ICs (显示 DNAI1 抗体) of pleomorphic adenomas.
Plag1 disruption in mouse differentially affects pre- and postnatal growth and development of organs, with reproductive repercussions
aP2 (显示 TFAP2A 抗体)-Cre-mediated expression activation of an oncogenic PLAG1 transgene results in cavernous angiomatosis in mice.
Demonstrate upregulation of several genes associated with Igf and Wnt signalling in PLAG1-induced pleomorphic adenomas. Inactivation of Igf2 delays tumour development.
Suggest an important role for furin (显示 FURIN 抗体) in PLAG1-induced salivary gland tumorigenesis in mice.
results establish the oncogenic potential of PLAG1 in mammary glands of mice and point towards contributing roles of Igf and Wnt (显示 WNT2 抗体) signaling
distinct loci exist for growth and fatness in the two populations and identified HMGA1 (显示 HMGA1 抗体) and PLAG1 as strong candidate genes on SSC7 and SSC4, respectively.
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.
pleiomorphic adenoma gene 1
, zinc finger protein PLAG1-like
, pleiomorphic adenoma gene 1 protein
, zinc finger protein PLAG1
, COL1A2/PLAG1 fusion
, C2H2 zinc finger protein PLAG1