anti-Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) 抗体

Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. 再加上,我们可以发PLEKHG6 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PLEKHG6 55200 Q3KR16
PLEKHG6 213522 Q8R0J1
PLEKHG6    
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • 在线下订单
  • orders@antibodies-online.cn

antibodies-online.cn销售最多的anti-PLEKHG6 抗体

Showing 10 out of 49 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 FACS, IHC (p), WB Western blot analysis of MyoGEF Antibody (N-term) (ABIN390909) in NCI-H460 cell line lysates (35 µg/lane). MyoGEF (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma with MyoGEF Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 EIA, WB Western blot analysis of MyoGEF Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). MyoGEF (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6至8个工作日
$484.00
详细
非结合性 IHC, ELISA, WB   100 μL Log in to see 11至14个工作日
$390.50
详细
非结合性 IHC (p), WB Immunohistochemical staining of human placenta with PLEKHG6 polyclonal antibody  shows strong membranous staining positivity in trophoblastic cells. Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PLEKHG6 polyclonal antibody . 100 μL Log in to see 11至12个工作日
$577.33
详细
非结合性 WB   100 μL Log in to see 2至3个工作日
$289.00
详细
Biotin ELISA, WB   200 μL Log in to see 11至14个工作日
$1,101.83
详细
APC ELISA, WB   200 μL Log in to see 11至14个工作日
$1,101.83
详细
PE ELISA, WB   200 μL Log in to see 11至14个工作日
$1,101.83
详细
FITC ELISA, WB   200 μL Log in to see 11至14个工作日
$1,101.83
详细
Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 11至14个工作日
$1,101.83
详细

更多抗PLEKHG6的相互作用对抗体

Human Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) interaction partners

  1. Ezrin interacts with MYOGEF and recruits it to retracting blebs, where MYOGEF activates RhoA and promotes the reassembly of the cortical actomyosin network at the bleb membrane, thus contributing to the regulation of bleb retraction.

  2. Intramolecular interactions between MyoGEF domains act as an autoinhibitory mechanism for the regulation of MyoGEF functions.

  3. Taken together, these results suggest that aurora B coordinates with Plk1 to regulate MyoGEF activation and localization, thus contributing to the regulation of cytokinesis.

  4. GIPC1-MyoGEF complex formation plays an important role in regulating MDA-MB-231 breast cancer cell polarization and invasion.

  5. ezrin allows the local activation of RhoG at the apical pole of epithelial cells by recruiting upstream and downstream regulators of RhoG and that both PLEKHG6 and ezrin are required for efficient macropinocytosis

  6. Plk1 can regulate MyoGEF activity and localization, contributing to the regulation of cytokinesis

  7. MyoGEF cooperates with nonmuscle myosin IIA to regulate the polarity and invasion activity of breast cancer cells through activation of RhoA and RhoC.

Mouse (Murine) Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) interaction partners

  1. GIPC1-MyoGEF complex formation plays an important role in regulating MDA-MB-231 breast cancer cell polarization and invasion.

PLEKHG6 抗原简介

蛋白简介

Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.

Gene names and symbols associated with PLEKHG6

  • pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6) 抗体
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (Plekhg6) 抗体
  • BC026778 抗体
  • Gm155 抗体
  • MyoGEF 抗体

Protein level used designations for PLEKHG6

PH domain-containing family G member 6 , myosin interacting guanine nucleotide exchange factor , myosin-interacting guanine nucleotide exchange factor , pleckstrin homology domain-containing family G member 6

GENE ID SPECIES
55200 Homo sapiens
213522 Mus musculus
anti-PLEKHG6 (PLEKHG6) 抗体 精选生产商
您还需要查找其他产品吗?