anti-Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4) 抗体

The protein encoded by PLEKHG4 contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. 再加上,我们可以发和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PLEKHG4 25894 Q58EX7
PLEKHG4 102075  
PLEKHG4 307796  
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Showing 10 out of 37 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ELISA, WB Western blot analysis of extracts from COS7/K562 cells, using PLEKHG4 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 WB WB Image Sample (30 ug of whole cell lysate) A: JurKat 5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1至2个工作日
$358.60
详细
非结合性 WB   100 μL Log in to see 7至9个工作日
$507.83
详细
非结合性 ELISA, WB   100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 IHC, WB Immunohistochemical analysis of PLEKHG4 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the Western blot analysis of PLEKHG4 expression in SHSY5Y (A), HEK293T (B), K562 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 WB Western Blot analysis of PLEKHG4 expression in transfected 293T cell line by PLEKHG4 MaxPab polyclonal antibody.<br><br>Lane 1: PLEKHG4 transfected lysate(126.20 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Log in to see 11至12个工作日
$425.71
详细
小鼠 非结合性 WB Western Blot analysis of PLEKHG4 expression in transfected 293T cell line by PLEKHG4 MaxPab polyclonal antibody.<br><br>Lane 1: PLEKHG4 transfected lysate(126.61 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μg Log in to see 11至12个工作日
$440.00
详细
非结合性 ELISA, IHC, WB   100 μL Log in to see 16 Days
$181.73
详细
非结合性 WB   100 μL Log in to see 2至3个工作日
$429.00
详细
非结合性 WB   100 μL Log in to see 6至8个工作日
$431.20
详细

通过反应活性、应用领域、克隆类型和共轭标记 PLEKHG4 抗体

特性 应用范围 宿主 克隆类型 标记
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更多抗Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4的相互作用对抗体

Human Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4) interaction partners

  1. Role of the guanine nucleotide exchange factor (显示 RASGRF1 抗体) in Akt2 (显示 AKT2 抗体)-mediated plasma membrane translocation of GLUT4 (显示 SLC2A4 抗体) in insulin (显示 INS 抗体)-stimulated skeletal muscle.

  2. This letter suggested cerebellar ataxia due to a pentanucleotide repeat (TAGAA) expansion on the puratrophin-1 (PLEKHG4) gene on chromosome 16q-22.1.

  3. (TGGAA)(n) repeats in the insertion mutation of PLEKHG4 are related to the pathogenesis of SCA31 (显示 BEAN1 抗体)

  4. Spinocerebellar ataxia type 4 (SCA4) is mapped to chromosome 16q22.1 in northern germany.Haplotype analyses refined the gene locus to a 3.69 cM interval between D16S3019 and D16S512.

  5. the autosomal dominant cerebellar ataxia that we have characterized is allelic with SCA4 and Japanese 16q-linked ADCA (显示 PDYN 抗体) type III.

  6. puratrophin-1 has a role in intracellular signaling and actin dynamics at the Golgi apparatus

  7. Mutations of the puratrophin1 gene on chromosome 16q22.1 are not a common genetic cause of cerebellar ataxia in a European population.

  8. We found the C-to-T substitution in the puratrophin-1 gene in 20 patients with ataxia (16 heterozygotes and four homozygotes) and four asymptomatic carriers in 9 of 24 families with an unknown type of ADCA (显示 PDYN 抗体).

  9. among 686 autosomal dominant spinocerebellar ataxia families in our cohort, 57 families were identified to have 65 affected individuals, who carried the C-to-T substitution of the puratrophin-1 gene

  10. Disease locus of 16q-autosomal dominant cerebellar ataxia was definitely confined to a 900-kb genomic region between the SNP04 and the -16C>T substitution in the puratrophin-1 gene in 16q22.1.

Mouse (Murine) Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4) interaction partners

  1. Role of the guanine nucleotide exchange factor (显示 ARHGEF12 抗体) in Akt2 (显示 AKT2 抗体)-mediated plasma membrane translocation of GLUT4 (显示 SLC2A4 抗体) in insulin (显示 INS 抗体)-stimulated skeletal muscle.

  2. Plekhg4 is an aggregation-prone member of the Dbl (显示 MCF2 抗体) family GEFs and regulation of GTPase (显示 RACGAP1 抗体) signaling is critical for proper cerebellar function

Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4) 抗原简介

蛋白简介

The protein encoded by this gene contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Mutations in this gene are associated with spinocerebellar ataxia 16q22-linked. Several alternatively spliced transcript variants, differing only in the 5' UTR, or encoding a different isoform, have been found for this gene.

Gene names and symbols associated with PLEKHG4

  • pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) 抗体
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 4 (Plekhg4) 抗体
  • pleckstrin homology and RhoGEF domain containing G4 (Plekhg4) 抗体
  • 4931414L13Rik 抗体
  • AI448583 抗体
  • ARHGEF44 抗体
  • mFLJ00068 抗体
  • PRTPHN1 抗体
  • RGD1310790 抗体
  • SCA4 抗体

Protein level used designations for PLEKHG4

PH domain-containing family G member 4 , Purkinje cell atrophy associated protein 1 , Purkinje cell atrophy-associated protein 1 , pleckstrin homology domain-containing family G member 4 , puratrophin-1

GENE ID SPECIES
25894 Homo sapiens
489759 Canis lupus familiaris
787892 Bos taurus
102075 Mus musculus
307796 Rattus norvegicus
anti-Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4) 抗体 精选生产商
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