PRKC, Apoptosis, WT1, Regulator (PAWR) ELISA试剂盒

The tumor suppressor WT1 represses and activates transcription. 再加上,我们可以发PAWR 抗体 (74)PAWR 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
PAWR 5074 Q96IZ0
PAWR 64513 Q62627
PAWR 114774 Q925B0
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6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Log in to see 15至18个工作日
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适于 PAWR 相互作用对的更多 ELISA 试剂盒

Human PRKC, Apoptosis, WT1, Regulator (PAWR) interaction partners

  1. we determined that increased miR-17-3P level plays crucial role in CRC (显示 CALR ELISA试剂盒) cells survival by targeting Par4, contributing to colorectal carcinogenesis.

  2. PAR4 is the target of mir-107 in colorectal cancer cells.

  3. we confirmed that the RASSF2-PAR-4 axis was mainly responsible for miR-7 functions in CAFs using bioinformatics methods. Overexpression of miR-7 in CAFs led to down-regulation of RASSF2, which dramatically decreased the secretion of PAR-4 from CAFs and then enhanced the proliferation and migration of the co-cultured cancer cells.

  4. we investigated in the present study the mechanisms regulating the accumulation of a 25kDa cleaved-Par-4 (cl-Par-4) fragment in ovarian and endometrial cancer cell lines

  5. Authors demonstrate that TRIM21 (显示 TRIM21 ELISA试剂盒) expression predicts survival in pancreatic cancer patients. This work highlights a novel mechanism of Par-4 regulation, and identifies a novel prognostic marker and potential therapeutic target for pancreatic cancer.

  6. Data suggest that PAR4 and P2Y12 (显示 P2RY12 ELISA试剂盒) heterodimer internalization/endocytosis is required for beta-arrestin-2 (显示 ARRB2 ELISA试剂盒) recruitment to endosomes and up-regulation of Akt (显示 AKT1 ELISA试剂盒) signaling; activation of PAR4 but not of P2Y12 (显示 P2RY12 ELISA试剂盒) drives internalization of the PAR4-P2Y12 (显示 P2RY12 ELISA试剂盒) heterodimer. (PAR4 = protease-activated receptor 4 (显示 F2RL3 ELISA试剂盒); P2Y12 (显示 P2RY12 ELISA试剂盒) = purinergic receptor P2Y (显示 P2RY1 ELISA试剂盒), G-protein coupled, 12 protein; Akt (显示 AKT1 ELISA试剂盒) = proto-oncogene (显示 RAB1A ELISA试剂盒) protein c-akt (显示 AKT1 ELISA试剂盒))

  7. In this review, we will focus on the therapeutic perspective of Par-4 with a special reference to its (Par-4) virgin prospect of devastating metastasis control.

  8. in vitro and in vivo upregulation of Par-4 expression is indispensable for the trafficking of GRP78 (显示 HSPA5 ELISA试剂盒) to the cell membrane and subsequent apoptosis of cancer cell

  9. Prostate apoptosis response 4 (PAR4) expression modulates WNT (显示 WNT2 ELISA试剂盒) signaling pathways in MCF7 breast cancer cells: A possible mechanism underlying PAR4-mediated docetaxel chemosensitivity.

  10. Decreased PAR4 expression in breast cancer is associated with shorter survival. PAR4 suppresses growth and invasiveness of breast cancer cells.

Mouse (Murine) PRKC, Apoptosis, WT1, Regulator (PAWR) interaction partners

  1. Induced by endoplasmic reticulum stress Par-4 (显示 F2RL3 ELISA试剂盒) acts as an important defense mechanism against mycobacterial infection and regulates cancer.

  2. Findings reveal a novel role for Par-4 (显示 F2RL3 ELISA试剂盒)/NF-kappaB (显示 NFKB1 ELISA试剂盒) in islet beta cell apoptosis and type 2 diabetes.

  3. Par4 (显示 F2RL3 ELISA试剂盒), CEBPB (显示 CEBPB ELISA试剂盒) and FAK (显示 PTK2 ELISA试剂盒) form a senescence signaling pathway, playing roles in modulating cell survival, growth, apoptosis, EMT (显示 ITK ELISA试剂盒) and self-renewal

  4. a novel mechanism of apoptosis induction by PAR-4 (显示 F2RL3 ELISA试剂盒)/ceramide-enriched exosomes, which may critically contribute to Alzheimer disease.

  5. extracellular Par-4 (显示 F2RL3 ELISA试剂盒)/SAC (显示 ADCY10 ELISA试剂盒) is systemically functional in inhibition of tumor growth and metastasis progression.

  6. loss of PAR4 (显示 F2RL3 ELISA试剂盒) leads to a reduction in the ability of tumour necrosis factor-alpha (显示 TNF ELISA试剂盒) to induce apoptosis by increased activation of NF-kappaB (显示 NFKB1 ELISA试剂盒)

  7. Antisense knockdown of PAR-4 (显示 F2RL3 ELISA试剂盒) or inhibition of ceramide biosynthesis reduced stem cell apoptosis; PAR-4 (显示 F2RL3 ELISA试剂盒) overexpression and treatment with ceramide analogs elevated apoptosis.

  8. AATF (显示 AATF ELISA试剂盒) is an endogenous antagonist of Par-4 (显示 F2RL3 ELISA试剂盒) activity and an effective inhibitor of aberrant amyloid beta 1-42 production and secretion under apoptotic conditions.

  9. Par-4 (显示 F2RL3 ELISA试剂盒) is directly involved in regulating choline uptake by interacting with CHT1 (显示 ChT ELISA试剂盒) and by reducing its incorporation on the cell surface

  10. the mechanism for Ras-mediated down-regulation of Par-4 (显示 F2RL3 ELISA试剂盒) is by promoter methylation

PAWR 抗原简介

Antigen Summary

The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

Gene names and symbols associated with PAWR

  • pro-apoptotic WT1 regulator (PAWR) 抗体
  • PRKC, apoptosis, WT1, regulator L homeolog (pawr.L) 抗体
  • PRKC, apoptosis, WT1, regulator (pawr) 抗体
  • pro-apoptotic WT1 regulator (Pawr) 抗体
  • PRKC, apoptosis, WT1, regulator (Pawr) 抗体
  • 2310001G03Rik 抗体
  • MGC81382 抗体
  • Par-4 抗体
  • Par4 抗体
  • PAWR 抗体
  • pawrl 抗体
  • zgc:103513 抗体

Protein level used designations for PAWR

PRKC, apoptosis, WT1, regulator , PAR-4 , PRKC apoptosis WT1 regulator protein , PRKC, apoptosis, WT1, regulator like , WT1-interacting protein , prostate apoptosis response 4 protein , prostate apoptosis response protein 4 , prostate apoptosis response protein PAR-4 , prostate apoptosis response-4 , transcriptional repressor PAR4 , Prostate apoptosis response protein 4 , par-4 induced by effectors of apoptosis , transcriptional repressor Par-4-like protein PAWR

GENE ID SPECIES
417870 Gallus gallus
447443 Xenopus laevis
449994 Danio rerio
452094 Pan troglodytes
532789 Bos taurus
695617 Macaca mulatta
5074 Homo sapiens
64513 Rattus norvegicus
114774 Mus musculus
611487 Canis lupus familiaris
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