anti-Oxysterol Binding Protein-Like 5 (OSBPL5) 抗体

OSBPL5 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. 再加上,我们可以发Oxysterol Binding Protein-Like 5 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
OSBPL5 361686  
OSBPL5 114879 Q9H0X9
OSBPL5 79196 Q9ER64
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产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
山羊 非结合性 ELISA, IHC, WB ABIN190918 (2µg/ml) staining of human spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN190918 (0.2µg/ml) staining of Human Spleen lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. 100 μg 6至7个工作日
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非结合性 ICC, IF, IHC, IHC (p), WB 100 μL 11至14个工作日
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山羊 非结合性 WB   0.1 mg 11 Days
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山羊 非结合性 ELISA, WB 0.1 mg 2至3个工作日
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小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (36.67 KDa) . 50 μL 11至12个工作日
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山羊 非结合性 ELISA, WB 200 μL 7至11个工作日
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山羊 Alkaline Phosphatase (AP) ELISA, WB   100 μL 16 Days
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山羊 APC ELISA, WB   100 μL 16 Days
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山羊 Biotin ELISA, WB   100 μL 16 Days
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山羊 FITC ELISA, WB   100 μL 16 Days
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引用最多的anti-Oxysterol Binding Protein-Like 5 抗体

  1. Human Polyclonal OSBPL5 Primary Antibody for ELISA, WB - ABIN188711 : Higashimoto, Soejima, Yatsuki, Joh, Uchiyama, Obata, Ono, Wang, Xin, Zhu, Masuko, Ishino, Hatada, Jinno, Iwasaka, Katsuki, Mukai: Characterization and imprinting status of OBPH1/Obph1 gene: implications for an extended imprinting domain in human and mouse. in Genomics 2002 (PubMed)
    Show all 2 Pubmed References

更多抗Oxysterol Binding Protein-Like 5的相互作用对抗体

Cow (Bovine) Oxysterol Binding Protein-Like 5 (OSBPL5) interaction partners

  1. imprinting status of four cattle genes (Tssc4,Nap1l4, Phlda2 and Osbpl5) in seven types of tissues, were assessed in cattle.

Human Oxysterol Binding Protein-Like 5 (OSBPL5) interaction partners

  1. ORP5/8 recruitment to the plasma membrane occurs through interactions with the N-terminal Pleckstrin homology domains and adjacent basic residues of ORP5/8 with both phosphatidylinositol 4-phosphate and Phosphatidylinositol 4,5-bisphosphate.

  2. Data suggest that ORP5/OSBPL5 promotes cell proliferation, cell motility, and invasiveness of neoplasm cells; this effect of ORP5/OSBPL5 depends on functional OSBP-related domain (ORD). ORP5/OSBPL5 is needed for activation of mTORC1 signaling and for transport of mTOR to lysosomes. (mTORC1 = mechanistic target of rapamycin complex-1; mTOR = mechanistic target of rapamycin)

  3. ORP5/8 regulate Ca(2+) signaling at specific membrane contact sites foci.

  4. ORP5/8 are endoplasmic reticulum (ER) membrane proteins implicated in lipid trafficking that localize to ER-plasma membrane (PM) contacts and maintain membrane homeostasis. Here the authors show that PtdIns(4,5)P 2 plays a critical role in the targeting and function of ORP5/8 at the PM.

  5. mammalian ORP5 and ORP8 proteins localize to ER-mitochondrial MCS, in addition to ER-PM contact sites.

  6. Results show that OSBPL5 and CALU were expressed at higher levels in the lung tissues of metastasis-positive cases than that in the metastasis-negative cases suggesting they can promote invasiveness of lung cancer cells.

  7. ORP5 and ORP8 could mediate PI4P/phosphatidylserine (PS) countertransport between the endoplasmic reticulum (ER) and the plasma membrane (PM), thus delivering PI4P to the ER-localized PI4P phosphatase Sac1 for degradation and PS from the ER to the PM.

  8. ORP5 may cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes.

  9. OBPH1/Obph1 gene is imprinted, with preferential expression from the maternal allele in human and mouse.

  10. Telomeric NAP1L4 and OSBPL5 of the KCNQ1 cluster, and the DECORIN gene are not imprinted in human trophoblast stem cells.

  11. OSBPL5 is relatd to invasion and poor prognosis in pancreatic cancer.

Mouse (Murine) Oxysterol Binding Protein-Like 5 (OSBPL5) interaction partners

  1. OBPH1/Obph1 gene is imprinted, with preferential expression from the maternal allele in human and mouse.

  2. OSBP regulates hepatic TG metabolism and suggest the involvement of OSBP in the insulin signaling pathways that control hepatic lipogenesis.

Oxysterol Binding Protein-Like 5 (OSBPL5) 抗原简介

蛋白简介

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with OSBPL5

  • oxysterol binding protein-like 5 (Osbpl5) 抗体
  • oxysterol binding protein like 5 (OSBPL5) 抗体
  • oxysterol binding protein like 5 (osbpl5) 抗体
  • 1110006M06Rik 抗体
  • AI462538 抗体
  • MGC109308 抗体
  • Obph1 抗体
  • ORP5 抗体
  • Osbp2 抗体
  • OSBPL5 抗体

Protein level used designations for OSBPL5

oxysterol binding protein-like 5 , oxysterol-binding protein-related protein 5-like , ORP-5 , OSBP-related protein 5 , oxysterol-binding protein homolog 1 , oxysterol-binding protein homologue 1 , oxysterol-binding protein-related protein 5 , oxysterol binding protein 2 , oxysterol binding protein homolog 1 , oxysterol-binding protein-like protein 5

GENE ID SPECIES
361686 Rattus norvegicus
483671 Canis lupus familiaris
532690 Bos taurus
770816 Gallus gallus
100431919 Pongo abelii
100466215 Ailuropoda melanoleuca
100515995 Sus scrofa
100539452 Meleagris gallopavo
100564429 Anolis carolinensis
114879 Homo sapiens
79196 Mus musculus
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