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NPC1 ELISA试剂盒

NPC1 encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain.

5 results:

NPC1 ELISA 试剂盒 (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Lysate, Tissue Homogenate
产品编号 ABIN6958195
$810.53
加上运输费 $45.00
96 tests
local_shipping 发货至: 美国
9至11个工作日

NPC1 ELISA 试剂盒 (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 Colorimetric Sandwich ELISA Cell Culture Supernatant, Cell Samples, Plasma, Serum, Tissue Lysate
产品编号 ABIN6951470
$501.60
加上运输费 $45.00
96 tests
local_shipping 发货至: 美国
21至31个工作日

NPC1 ELISA 试剂盒 (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 小鸡 Colorimetric Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
产品编号 ABIN1056422
$707.14
加上运输费 $45.00
96 tests
local_shipping 发货至: 美国
12至15个工作日

NPC1 ELISA 试剂盒 (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 猴 Colorimetric Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
产品编号 ABIN1056423
$707.14
加上运输费 $45.00
96 tests
local_shipping 发货至: 美国
12至15个工作日

NPC1 ELISA 试剂盒 (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 绵羊 Colorimetric Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
产品编号 ABIN1056424
$707.14
加上运输费 $45.00
96 tests
local_shipping 发货至: 美国
12至15个工作日
  • 类型 Kit
    • Kit
  • 抗原 Niemann-Pick Disease, Type C1 (NPC1)
    • Niemann-Pick Disease, Type C1 (NPC1)
    • Interferon gamma (IFNG)
    • Histone 3 (H3)
    • Interleukin 10 (IL10)
    • Epidermal Growth Factor Receptor (EGFR)
    • Interleukin 4 (IL4)
    • Interleukin 6 (IL6)
    • Tumor Necrosis Factor alpha (TNF)
    • Interleukin 1, beta (IL1B)
    • Tumor Protein P53 (TP53)
    • Interleukin 2 (IL2)
    • Transforming Growth Factor, beta 1 (TGFB1)
    • IgG
    • Interleukin 8 (IL8)
    • Albumin (ALB)
    • Follicle-Stimulating Hormone (FSH)
    • C-Reactive Protein (CRP)
    • Leptin (LEP)
    • IgA
    • Interleukin 1 alpha (IL1A)
    • Jun Proto-Oncogene (JUN)
    • Interleukin 13 (IL13)
    • Interleukin 17A (IL17A)
    • Interleukin 5 (IL5)
    • Adiponectin (ADIPOQ)
    • Insulin (INS)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Thrombomodulin (THBD)
    • CD40 Ligand (CD40LG)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Chemokine (C-C Motif) Ligand 5 (CCL5)
    • Cortisol
    • Annexin A5 (ANXA5)
    • Intercellular Adhesion Molecule 1 (ICAM1)
    • Interleukin 12 (IL12)
    • Luteinizing Hormone (LH)
    • Metalloproteinase Inhibitor 2 (TIMP2)
    • Cystatin C (CST3)
    • Interferon alpha (IFNA)
    • Prolactin (PRL)
    • Retinol Binding Protein 4, Plasma (RBP4)
    • Interleukin 1 Receptor Antagonist (IL1RN)
    • Platelet-Derived Growth Factor beta Polypeptide (PDGFB)
    • Thyroxine T4 (T4)
    • Complement Component 3 (C3)
    • Erythropoietin (EPO)
    • Insulin-Like Growth Factor 2 (IGF2)
    • Transforming Growth Factor, beta 2 (TGFB2)
    • Caspase 3 (CASP3)
    • Fas Ligand (TNF Superfamily, Member 6) (FASL)
    • Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9)
  • 应用范围
    • ELISA
  • 适用
    • 小鸡
    • 绵羊
  • 图像
  • 实验类型
    • Sandwich ELISA
  • Analytical Method
    • Quantitative
  • 检测方法
    • Colorimetric
  • Plate
    • Pre-coated
  • 样本
    • Cell Culture Supernatant
    • Plasma
    • Serum
    • Tissue Homogenate
    • Cell Lysate
    • Cell Samples
    • Tissue Lysate

NPC1 抗原简介

蛋白简介

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.

Gene names and symbols associated with NPC1

  • NPC intracellular cholesterol transporter 1 (NPC1) 抗体
  • Niemann-Pick disease, type C1 (npc1) 抗体
  • Niemann-Pick C1 protein (LOC579887) 抗体
  • NPC intracellular cholesterol transporter 1 (Npc1) 抗体
  • A430089E03Rik 抗体
  • C85354 抗体
  • Cdig2 抗体
  • D18Ertd139e 抗体
  • D18Ertd723e 抗体
  • im:7149020 抗体
  • lcsd 抗体
  • nmf164 抗体
  • NPC 抗体
  • spm 抗体
  • wu:fb53a12 抗体
  • wu:fc29a12 抗体

Protein level used designations for NPC1

Niemann-Pick C1 protein , Niemann-Pick type C1 disease protein , Nasopharyngeal carcinoma 1 , Niemann-Pick C1 , Niemann-Pick disease, type C1 , sphingomyelinosis , Niemann-Pick C disease protein

GENE ID SPECIES
403698 Canis lupus familiaris
455338 Pan troglodytes
493693 Felis catus
553330 Danio rerio
579887 Strongylocentrotus purpuratus
100008746 Oryctolagus cuniculus
18145 Mus musculus
4864 Homo sapiens
397591 Sus scrofa
421076 Gallus gallus
266732 Rattus norvegicus
100718604 Cavia porcellus

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