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NKRF encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. 再加上，我们可以发NFKB Repressing Factor 试剂盒 (10) 和 NFKB Repressing Factor 蛋白 (7)和数多这个蛋白质的别的产品。
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vitamin E supplementation affords protection by decreasing MMP-1 (显示 MMP1 抗体) and increasing PPARg (显示 PPARG 抗体), GSTa (显示 GSTa2 抗体), and ABCA1 (显示 ABCA1 抗体) levels in aortae of rabbits fed a cholesterol-rich diet
MIR29 targets and reduces expression of CLDN1 (显示 CLDN1 抗体) and NKRF to increase intestinal permeability in inflammatory bowel disease.
The data of this study show that JKTBP1 and the 14-nt element act independently to mediate NRF internal ribosome entry segment activity.
NKRF is a nucleolar HSP essential for nucleolus homeostasis and cell survival under proteotoxic stress. NKRF is a thermosensor translocating from the nucleolus to the nucleoplasm during heat stress; nucleolar pools are replenished upon HSF1 (显示 HSF1 抗体)-mediated NKRF resynthesis. NKRF is an unconventional HSP crucial for correct rRNA processing. Under stress conditions, NKRF directs XRN2 (显示 XRN2 抗体) nucleolus/nucleoplasm trafficking.
Data suggest that L protein from LCMV interactions with host proteome, specifically DDX3X (显示 DDX3X 抗体), NKRF, and TRIM21 (显示 TRIM21 抗体). (LCMV = Lymphocytic choriomeningitis mammarenavirus; DDX3X (显示 DDX3X 抗体) = DEAD-box helicase 3; NKRF = NF-kappa-B-repressing factor; TRIM21 (显示 TRIM21 抗体) = tripartite motif-containing protein-21 (显示 TRIM21 抗体))
depletion of NKRF, XRN2 (显示 XRN2 抗体) or DHX15 (显示 DHX15 抗体) impairs an early pre-rRNA cleavage step.
NF-kappaB-repressing factor (NKRF) phosphorylation modulates promoter-proximal transcription elongation of NF-kappaB (显示 NFKB1 抗体)/NKRF-regulated genes via direct interactions with elongation complex in response to specific stimuli
The up-regulated NKRF serves as an endogenous repressor for IP-10 (显示 CXCL10 抗体) and IL-8 (显示 IL8 抗体) synthesis to hinder host from robust response to MTb (显示 NCAPG2 抗体) infection.
NRF may serve as an endogenous repressor to prevent robust increase in IP-10/CXCL10 (显示 CXCL10 抗体) and IL-8/CXCL8 (显示 IL8 抗体) when TB bacterial load is high.
The expression of NKRF is decreased in PBMCs of patients with stable COPD (显示 ARCN1 抗体). The downregulation of NKRF was found to be closely related to enhanced IL-8 (显示 IL8 抗体) production from these peripheral blood cells through de-repression of the IL-8 (显示 IL8 抗体) promoter.
The results indicate that JKTBP1 regulates the level of NRF protein expression by binding to both NRF 5' and 3' UTRs.
role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene
GRK5 overexpression causes nuclear accumulation of IkappaB alpha, leading to the inhibition of NFkappaB transcriptional activity.
This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants.
NFKB repressing factor
, transcription factor NRF
, NF-kappaB repressing factor
, nkrf (NF-kappaB repressing factor)
, NF-kappa-B-repressing factor-like
, NF-kappa-B-repressing factor
, NFkB-repressing factor