NAE1 抗体
(NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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NAE1 抗体 by 适用
Find NAE1 抗体 for a variety of species such as anti-Human NAE1, anti-Mouse NAE1, anti-Rat NAE1. The species listed below are among those available. Click on a link to go to the corresponding products.
NAE1 抗体 by 应用范围
Find NAE1 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.
NAE1 抗体 by 抗体来源
Find NAE1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
NAE1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal NAE1 抗体. Click on a link to go to the corresponding products.
NAE1 抗体 by 克隆
Find NAE1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular NAE1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN563865
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7161137
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN563864
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN948746
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN391418
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (3)
Cat. No.
ABIN359509
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7240514
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6750418
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN7260999
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN656991
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN950470
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC
Validations
Cat. No.
ABIN1714592
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1701090
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN1708482
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1712107
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our NAE1 抗体
: "PPARγ neddylation essential for adipogenesis is a potential target for treating obesity." in: Cell death and differentiation, Vol. 23, Issue 8, pp. 1296-311, (2016) (PubMed).: "More than the sum of its parts." in: Cell reports, Vol. 1, Issue 1, pp. 1, (2012) (PubMed).
: "A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924." in: Cell reports, Vol. 1, Issue 4, pp. 309-16, (2012) (PubMed).
: "Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8." in: Nature, Vol. 422, Issue 6929, pp. 330-4, (2003) (PubMed).
: "ASPP2 inhibits APP-BP1-mediated NEDD8 conjugation to cullin-1 and decreases APP-BP1-induced cell proliferation and neuronal apoptosis." in: Journal of neurochemistry, Vol. 85, Issue 3, pp. 801-9, (2003) (PubMed).
: "APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain." in: The Journal of cell biology, Vol. 163, Issue 1, pp. 27-33, (2003) (PubMed).
: "The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons." in: The Journal of biological chemistry, Vol. 275, Issue 12, pp. 8929-35, (2000) (PubMed).
: "Covalent modification of all members of human cullin family proteins by NEDD8." in: Oncogene, Vol. 18, Issue 48, pp. 6829-34, (2000) (PubMed).
: "APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein." in: The Journal of biological chemistry, Vol. 271, Issue 19, pp. 11339-46, (1996) (PubMed).
Aliases for NAE1 抗体
beta-Amyloid precursor protein binding protein 1 (APP-BP1) 抗体NEDD8 activating enzyme E1 subunit 1 (NAE1) 抗体
NEDD8 activating enzyme E1 subunit 1 (Nae1) 抗体
NEDD8 activating enzyme E1 subunit 1 S homeolog (nae1.S) 抗体
nedd8 activating enzyme E1 subunit 1 (nae1) 抗体
NEDD8-activating enzyme E1 regulatory subunit (ula-1) 抗体
59kDa 抗体
A-116A10.1 抗体
anon-WO0140519.225 抗体
APPBP1 抗体
Appbp1 抗体
appbp1 抗体
CG7828 抗体
dAPP-BP1 抗体
dAPPBP1 抗体
Dmel\\CG7828 抗体
ula-1 抗体
zgc:66148 抗体
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