(Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2))
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012].
Komarova, Lansbergen, Galjart, Grosveld, Borisy, Akhmanova: "EB1 and EB3 control CLIP dissociation from the ends of growing microtubules." in: Molecular biology of the cell, Vol. 16, Issue 11, pp. 5334-45, (2005) (PubMed).
Aliases for MAPRE2 抗体
microtubule associated protein RP/EB family member 2 (MAPRE2) 抗体 microtubule-associated protein, RP/EB family, member 2 (Mapre2) 抗体 microtubule associated protein RP/EB family member 2 S homeolog (mapre2.S) 抗体 AI314113 抗体 C820009F03Rik 抗体 D18Abb1e 抗体 DKFZp459O163 抗体 EB1 抗体 EB2 抗体 MAPRE2 抗体 mapre2-A 抗体 RP1 抗体