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The protein encoded by MBD1 is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). 再加上，我们可以发MBD1 抗体 (102) 和 MBD1 蛋白 (4)和数多这个蛋白质的别的产品。
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Dihydrofolate reductase (显示 DHFR ELISA试剂盒) and thymidylate synthase (显示 TYMS ELISA试剂盒) form a complex in vitro and co-localize in normal and cancer cells.
MBD1 (显示 DPEP1 ELISA试剂盒) may be a tumor suppressor gene in advanced colorectal cancer (CRC (显示 CALR ELISA试剂盒))and affect the development and metastasis of CRC (显示 CALR ELISA试剂盒) by regulating 8 tumor suppressor genes through binding with SP1 (显示 PSG1 ELISA试剂盒).
Our findings imply that reduced stability and enhanced dynamics of MBD1 (显示 DPEP1 ELISA试剂盒) or MBD6 is the origin of ATP7B (显示 ATP7B ELISA试剂盒) dysfunction in Wilson disease patients with the G85V or G591D mutation.
Single nucleotide polymorphism in DHFR (显示 DHFR ELISA试剂盒) gene is associated with Systemic lupus erythematosus.
study concludes polymorphism 63/91 in DHFR (显示 DHFR ELISA试剂盒) gene promoter can modulate the onset of methotrexate-related adverse effects in rheumatoid arthritis patients
our findings suggest that the identification of DHFR (显示 DHFR ELISA试剂盒) polymorphisms in the promoter region of the gene may be helpful in tailoring MTX (显示 MTX1 ELISA试剂盒) doses for ALL pediatric patients on maintenance therapy.
The abundance of dihydrofolate reductase (显示 DHFR ELISA试剂盒) was statistically significantly increased in rheumatoid arthritis (RA)-patient biopsies compared with controls and correlated with the administered dosage of methotrexate (MTX (显示 MTX1 ELISA试剂盒)), the most frequently prescribed immunosuppressive drug for RA.
MBD1 (显示 DPEP1 ELISA试剂盒) regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner.
the binding of MBD1 (显示 DPEP1 ELISA试剂盒) to nucleosomes demonstrates sequence preferences depending on the position of the methyl groups on the nucleosome.
The present study demonstrated that ADAR1 (显示 ADAR ELISA试剂盒) positively regulates the expression of DHFR (显示 DHFR ELISA试剂盒) by editing the miR (显示 MLXIP ELISA试剂盒)-25-3p and miR (显示 MLXIP ELISA试剂盒)-125a-3p binding sites in the 3'-UTR (显示 UTS2R ELISA试剂盒) of DHFR (显示 DHFR ELISA试剂盒), enhancing cellular proliferation and resistance to methotrexate in MCF-7 cells.
MBD1 (显示 DPEP1 ELISA试剂盒) has a role in neural stem cell maintenance and epigenetic regulation.
MBD1 targets short interspersed nuclear elements, but does not exclude RNA Polymerase III.
We demonstrated the importance of Aire's interaction with the ATF7ip-MBD1 (显示 DPEP1 ELISA试剂盒) protein complex in maintaining central tolerance
H19 (显示 NCKAP1 ELISA试剂盒) lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1 (显示 DPEP1 ELISA试剂盒).
regulatory loop formed by MBD1 (显示 DPEP1 ELISA试剂盒) and miR (显示 MLXIP ELISA试剂盒)-195 is an important component of the epigenetic network that controls aNSC fate
MBD1, miR-184, and Numbl form a regulatory network that helps control the balance between proliferation and differentiation of adult neural stem/progenitor cells.
Results indicate that MBD1 (显示 DPEP1 ELISA试剂盒) can interpret the CpG dinucleotide as a repressive signal in vivo regardless of its methylation status.
These data show, for the first time, the involvement of methyl-CpG binding domain proteins in the regulation of the MAGE-A genes.
Mbd1 (显示 DPEP1 ELISA试剂盒)(-/-) mice exhibit several core deficits associated with autism, including reduced social interaction, learning deficits, anxiety, defective sensory motor gating, depression and abnormal brain serotonin activity.
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions\; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides\; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
CXXC-type zinc finger protein 3
, methyl-CpG binding domain protein 1 isoform PCM1
, methyl-CpG-binding domain protein 1
, protein containing methyl-CpG-binding domain 1
, the regulator of fibroblast growth factor 2 (FGF-2) transcription
, methyl-CpG-binding protein MBD1
, coiled-coil domain containing 11