Melanoma Inhibitory Activity Protein 2 (MIA2) ELISA试剂盒

The protein encoded by MIA2 is a tumor-associated antigen found in cutaneous T-cell lymphoma and several other cancers. 再加上,我们可以发MIA2 抗体 (91)MIA2 蛋白 (16)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MIA2 4253 O15320
MIA2 338320 Q91ZV0
大鼠 MIA2 MIA2 362743  
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产品编号 适用 灵敏度 范围 图像 规格 交付 价格 详细
0.156 ng/mL 0.625-40 ng/mL Typical standard curve 96 Tests 15至18个工作日
$910.56
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小鼠 19.5 pg/mL 78.1-5000 pg/mL   96 Tests 15至18个工作日
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Human Melanoma Inhibitory Activity Protein 2 (MIA2) interaction partners

  1. These data showed that the NRZ tether is required for TANGO1 to assemble into a ring and indicated that stable complexes of TANGO1, cTAGE5 and TANGO1-short, recruit the tether.

  2. TANGO1/CTAGE5 receptor serves as a polyvalent template for assembly of large COPII coats.

  3. In this study, we identified specific and critical residues in the Sec12-binding region of cTAGE5 (E75A K76A, K89A, and S97A) and confirmed that cTAGE5-mediated Sec12 accumulation at ER exit sites is required for collagen VII secretion.

  4. Data indicate that MIA2 represents a potential novel acute phase protein and MIA2 expression responds to liver damage in chronic liver diseases.

  5. The novel gene MIA2 acts as a tumour suppressor in hepatocellular carcinoma.

  6. population and bioinformatic analysis of MGEA6 P521A variation as a risk factor for Fahr's disease; genetic screen data show this mutation is very rare; bioinformatics analysis provided conflicting findings

  7. cTAGE5 forms a complex with TANGO1 (MIA3), a previously characterized cargo receptor for collagen VII

  8. HBx activates hepatoma cell growth and proliferation through repression of the potential tumor suppressor MIA2.

  9. 22 members of an Iranian family with basal ganglia calfication as well as 100 controls were genotyped for the C>G P521A variant of CTAGE5, but none were found.

  10. Findings suggest that the roles of MIA2 might be based on the variety of the integrins and the subtypes of mitogen-activated protein kinase in oral carcinoma.

  11. Sec12 recruitment to endoplasmic reticulum exit sites is organized by its direct interaction with cTAGE5, a previously characterized collagen cargo receptor component, which functions together with TANGO1 at endoplasmic reticulum exit sites.

  12. These findings define an interaction between the common MIA2(I141M) variant and the ER stress/UPR system and specify a subgroup of PDAC patients who are more likely to benefit from adjuvant chemotherapy.

Mouse (Murine) Melanoma Inhibitory Activity Protein 2 (MIA2) interaction partners

  1. Conditional knockout of cTAGE5/MEA6 in the brain leads to severe defects in neural development, including deficits in dendrite outgrowth and branching, spine formation and maintenance, astrocyte activation, and abnormal behaviors

  2. cTAGE5 deletion in pancreatic beta cells impairs proinsulin trafficking and insulin biogenesis in mice.

  3. Mia2 is a novel, hepatic, endoplasmic reticulum-to-Golgi trafficking protein that regulates cholesterol metabolism.

MIA2 抗原简介

Antigen Summary

The protein encoded by this gene is a tumor-associated antigen found in cutaneous T-cell lymphoma and several other cancers. Autoantibodies against the encoded protein have been found in some cancers. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MIA2

  • melanoma inhibitory activity 2 (MIA2) 抗体
  • CTAGE family, member 5 (ctage5) 抗体
  • melanoma inhibitory activity 2 (Mia2) 抗体
  • MEA6 抗体
  • MGEA 抗体
  • MGEA6 抗体
  • MGEA11 抗体
  • zgc:56047 抗体

Protein level used designations for MIA2

cTAGE family member 5 , cutaneous T-cell lymphoma-associated antigen 5 , meningioma expressed antigen 6 (coiled-coil proline-rich) , meningioma-expressed antigen 6/11 , protein cTAGE-5 , melanoma inhibitory activity protein 2

GENE ID SPECIES
4253 Homo sapiens
393281 Danio rerio
338320 Mus musculus
362743 Rattus norvegicus
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