Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) ELISA试剂盒

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. 再加上,我们可以发Matrix Metallopeptidase 13 (Collagenase 3) 抗体 (289)Matrix Metallopeptidase 13 (Collagenase 3) 蛋白 (42)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MMP13 4322 P45452
MMP13 17386 P33435
MMP13 171052  
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
0.113 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13至16个工作日
$530.53
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小鼠 28 pg/mL 78 pg/mL - 5000 pg/mL 96 Tests Log in to see 13至16个工作日
$545.68
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大鼠 0.063 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13至16个工作日
$576.00
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23.44 pg/mL 93.75-6000 pg/mL Typical standard curve 96 Tests Log in to see 13至16个工作日
$1,026.67
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Pig 25.8 pg/mL 62.5 pg/mL - 4000 pg/mL 96 Tests Log in to see 13至16个工作日
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Cow 0.67 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests Log in to see 13至16个工作日
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小鸡 5.7 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests Log in to see 13至16个工作日
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山羊 1.26 ng/mL 3.12 ng/mL - 200 ng/mL 96 Tests Log in to see 13至16个工作日
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0.29 ng/mL 0.78 ng/mL - 50 ng/mL 96 Tests Log in to see 13至16个工作日
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Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15至18个工作日
$707.14
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引用最多的Matrix Metallopeptidase 13 (Collagenase 3) ELISA试剂盒

  1. Mouse (Murine) MMP13 ELISA Kit for Sandwich ELISA - ABIN415612 : Campo, Avenoso, Nastasi, Micali, Prestipino, Vaccaro, DAscola, Calatroni, Campo: Hyaluronan reduces inflammation in experimental arthritis by modulating TLR-2 and TLR-4 cartilage expression. in Biochimica et biophysica acta 2011 (PubMed)
    Show all 10 Pubmed References

  2. Human MMP13 ELISA Kit for Sandwich ELISA - ABIN921071 : Yang, Gao, Rao, Shen: Clinicopathological significance and prognostic value of MMP-13 expression in colorectal cancer. in Scandinavian journal of clinical and laboratory investigation 2012 (PubMed)
    Show all 9 Pubmed References

  3. ABIN1882517 : Bai, Merchant: A role for CITED2, a CBP/p300 interacting protein, in colon cancer cell invasion. in FEBS letters 2007 (PubMed)
    Show all 7 Pubmed References

  4. Mouse (Murine) MMP13 ELISA Kit - ABIN455834 : Campo, Avenoso, DAscola, Scuruchi, Prestipino, Calatroni, Campo: Hyaluronan in part mediates IL-1beta-induced inflammation in mouse chondrocytes by up-regulating CD44 receptors. in Gene 2012 (PubMed)
    Show all 5 Pubmed References

  5. Human MMP13 ELISA Kit for Sandwich ELISA - ABIN625055 : Toegel, Wu, Otero, Goldring, Leelapornpisid, Chiari, Kolb, Unger, Windhager, Viernstein: Caesalpinia sappan extract inhibits IL1?-mediated overexpression of matrix metalloproteinases in human chondrocytes. in Genes & nutrition 2012 (PubMed)
    Show all 4 Pubmed References

  6. Human MMP13 ELISA Kit for Sandwich ELISA - ABIN414818 : Mern, Fontana, Beierfuß, Thomé, Hegewald et al.: A combinatorial relative mass value evaluation of endogenous bioactive proteins in three-dimensional cultured nucleus pulposus cells of herniated intervertebral discs: identification of potential ... in PLoS ONE 2013 (PubMed)
    Show all 4 Pubmed References

  7. ABIN1882516 : Bedi, Fox, Kovacevic, Deng, Warren, Rodeo: Doxycycline-mediated inhibition of matrix metalloproteinases improves healing after rotator cuff repair. in The American journal of sports medicine 2010 (PubMed)
    Show all 4 Pubmed References

  8. Human MMP13 ELISA Kit for Sandwich ELISA - ABIN818166 : Duncan, Smith, Fleming, Partridge, Shimizu, Moran, Cooper: The Histone-Deacetylase-Inhibitor Suberoylanilide Hydroxamic Acid Promotes Dental Pulp Repair Mechanisms Through Modulation of Matrix Metalloproteinase-13 Activity. in Journal of cellular physiology 2015 (PubMed)
    Show all 3 Pubmed References

  9. Rat (Rattus) MMP13 ELISA Kit for Sandwich ELISA - ABIN365611 : Zheng, Zhong, Qin, Chen, Wu, Zeng, Ye, Li, Yuan, Yao, Chen: Advanced oxidation protein products induce inflammatory response in fibroblast-like synoviocytes through NADPH oxidase -dependent activation of NF-κB. in Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013 (PubMed)
    Show all 3 Pubmed References

  10. Rabbit MMP13 ELISA Kit for Sandwich ELISA - ABIN577622 : Aydin, Korkusuz, Korkusuz, Tezcaner, Bilgic, Yaprakci, Keskin: In vitro and in vivo evaluation of doxycycline-chondroitin sulfate/PCLmicrospheres for intraarticular treatment of osteoarthritis. in Journal of biomedical materials research. Part B, Applied biomaterials 2014 (PubMed)
    Show all 2 Pubmed References

适于 Matrix Metallopeptidase 13 (Collagenase 3) 相互作用对的更多 ELISA 试剂盒

Human Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. The present results suggested that Icariin may have a chondroprotective effect, exerted through the inhibition of MMP1 (显示 MMP1 ELISA试剂盒), MMP3 (显示 MMP3 ELISA试剂盒) and MMP13 via MAPK (显示 MAPK1 ELISA试剂盒) pathways. Therefore, Icariin may have potential as a novel therapeutic strategy for the treatment of osteoarthritis.

  2. MMP-13 may play a role on physiological turnover of cartilage extracellular matrix and that LRP1 (显示 LRP1 ELISA试剂盒) is a key modulator of extracellular levels of MMP-13 and its internalization is independent of the levels of ADAMTS-4 (显示 ADAMTS4 ELISA试剂盒), -5 and TIMP-3 (显示 TIMP3 ELISA试剂盒).

  3. proteolysis of collagen-rich natural extracellular matrix (ECM (显示 MMRN1 ELISA试剂盒)), performed uniquely by individual homologous proteases, leads to distinct events that eventually affect overall ECM (显示 MMRN1 ELISA试剂盒) morphology, viscoelastic properties, and molecular composition.

  4. A strong association between the -77 MMP-13 polymorphism and posterior tibial tendinopathy insufficiency.

  5. Data show that AJUBA (显示 AJUBA ELISA试剂盒) upregulated MMP10 (显示 MMP10 ELISA试剂盒) and MMP13 expression in esophageal squamous cell carcinoma (ESCC).

  6. TGF-beta1 (显示 TGFB1 ELISA试剂盒) stimulates the phosphorylation of Runx2 (显示 RUNX2 ELISA试剂盒) at three serine amino acids, and this event is required for MMP-13 expression in osteoblastic cells.

  7. IL-6 (显示 IL6 ELISA试剂盒)-stimulated MMP-13 expression was independent of IL-1beta (显示 IL1B ELISA试剂盒) stimulation and was blocked by SAHA, suggesting that SAHA inhibits IL-6 (显示 IL6 ELISA试剂盒) signaling in Osteoarthritis (OA) chondrocytes.

  8. High MMP13 expression is associated with intervertebral disc degeneration.

  9. data demonstrate that MMP-13 is critical for the development of osteolytic lesions in Multiple myeloma and that targeting the MMP-13 protein - rather than its catalytic activity - constitutes a potential approach to mitigating bone disease in affected patients.

  10. Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritic chondrocytes, which manifested in increased expression of ADAMTS5 (显示 ADAMTS5 ELISA试剂盒), MMP13, and decreased COL2A1 (显示 COL2A1 ELISA试剂盒) expression.

Mouse (Murine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. the phenotype seen in the Hdac4 (显示 HDAC5 ELISA试剂盒)(-/-) mice is partially derived from elevation in MMP-13 and may be due to a bone remodeling disorder caused by overexpression of this enzyme.

  2. MEF2C (显示 MEF2C ELISA试剂盒) is necessary for Mmp13 gene expression at the transcriptional level and participates in PTH (显示 PTH ELISA试剂盒)-stimulated Mmp13 gene expression by increased binding to c-FOS at the AP-1 (显示 JUN ELISA试剂盒) site in the Mmp13 promoter.

  3. data reveal a novel involvement of MMP-13 in regulating dendritic cell (DC) immunobiology through moderating MHC-I surface presentation, endocytosis and cytokine/chemokine (显示 CCL1 ELISA试剂盒) secretion; furthermore, the reduced MHC-I surface presentation by DCs resulted in a poor CD8 (显示 CD8A ELISA试剂盒)(+) T-cell response in vitro; MMP-13 might be a promising target for therapeutic intervention in inflammatory diseases

  4. The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (显示 DDR2 ELISA试剂盒)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (显示 DDR2 ELISA试剂盒) and matrix metalloproteinase 13.

  5. Postnatal chondrocyte-specific deletion of Hdac3 (显示 HDAC3 ELISA试剂盒) with an inducible Col2a1 (显示 COL2A1 ELISA试剂盒)-Cre caused premature production of pErk1/2 and Mmp13 in the growth plate.

  6. Mmp13 is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (显示 PTH ELISA试剂盒), and Osterix (显示 SP7 ELISA试剂盒) through distal enhancers.

  7. Our study contributes to the understanding of the role of HIF1alpha (显示 HIF1A ELISA试剂盒) in OA and highlights the HIF1alpha (显示 HIF1A ELISA试剂盒)-beta-catenin (显示 CTNNB1 ELISA试剂盒) interaction, thus providing new insights into the impact of hypoxia in articular cartilage.

  8. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (显示 MMP1 ELISA试剂盒)/protease-activated receptor-1 (显示 F2R ELISA试剂盒) axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  9. IL-1Ra (显示 IL1RN ELISA试剂盒) is associated with MMP-13 expression and has a novel function in such regulation without interference of the IL-1 (显示 IL1A ELISA试剂盒) signaling cascade.

  10. We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 expression and activity.

Cow (Bovine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. p38 (显示 MAPK14 ELISA试剂盒) phosphorylation and MMP13 expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.

  2. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  3. MMP-13 treatment of fresh articular cartilage results in cleaved fibromodulin (显示 FMOD ELISA试剂盒) fragments

  4. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 (显示 MMP1 ELISA试剂盒) and MMP-13 (follicular apex (显示 APEX1 ELISA试剂盒) vs. base) for the preovulatory collagenolysis required for follicle rupture

  5. involvement of p38 MAP kinase (显示 MAPK14 ELISA试剂盒) in the hyaluronan oligosaccharide induction of MMP-13

  6. MMP-13 and collagenase have roles in chondrocyte hypertrophy induced by type II collagen (显示 COL2A1 ELISA试剂盒)

  7. At high but naturally occurring concentrations the collagen peptide CB12 (显示 PABPC4 ELISA试剂盒)-II induced an increase in the expressions of MMP-13 and cleavage of type II collagen (显示 COL2A1 ELISA试剂盒) by collagenase in the mid zone and also in the superficial zone.

Xenopus laevis Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. XCL3 and XCL4 can be differentially induced by prolactin (显示 PRL ELISA试剂盒) and thyroid hormone (显示 PTH ELISA试剂盒)(3)

Zebrafish Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. MeHg impairs tail development at least partially by activation of the tissue remodeling proteases Mmp9 (显示 MMP9 ELISA试剂盒) and Mmp13.

  2. Zebra fish embryogenesis requires MMP-13 and dexamethasone and hydrocortisone modulate the expression of this gene, leading to increased activity and potentially contributing to subsequent dysmorphogenesis.

  3. JNK (显示 MAPK8 ELISA试剂盒)-Mmp13 signaling pathway plays an essential role in regulating the innate immune cell migration in response to severe injury in vivo

Rabbit Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. These results suggest that PEP-1-SIRT2 (显示 SIRT2 ELISA试剂盒) promotes matrix metalloproteinases-induced dedifferentiation via ERK (显示 MAPK1 ELISA试剂盒) signaling in articular chondrocytes.

  2. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 (显示 MMP3 ELISA试剂盒) and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage.

  3. Leptin (显示 LEP ELISA试剂盒) can induce MMP-13 and have a synergistic induction effect on NO with TNF-alpha (显示 TNF ELISA试剂盒) in rabbit articular chondrocytes in vitro.

Horse (Equine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. The DNA microarray analysis for matrix metalloproteinase (MMP)-related mRNA expression in equine superficial digital flexor tendinitis indicated that mRNA level of MMP-13 was apparently up-regulated in the tendinitis as compared to normal tendon.

Pig (Porcine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. TNF-alpha (显示 TNF ELISA试剂盒) induced MMP-13 expression by condylar cells might be involved in the degradation of the juvenile condyle.

Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) 抗原简介

Antigen Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene names and symbols associated with MMP13

  • matrix metallopeptidase 13 (MMP13) 抗体
  • matrix metallopeptidase 13 (Mmp13) 抗体
  • matrix metalloproteinase 7 (MGC68994) 抗体
  • matrix metallopeptidase 13a (mmp13a) 抗体
  • matrix metallopeptidase 13 (collagenase 3) like S homeolog (mmp13l.S) 抗体
  • matrix metallopeptidase 13 (collagenase 3) (mmp13) 抗体
  • matrix metalloproteinase 13 (LOC100136348) 抗体
  • matrix metallopeptidase 12 (MMP12) 抗体
  • matrix metalloproteinase 13 (mmp13) 抗体
  • matrix metallopeptidase 13 (mmp13) 抗体
  • matrix metallopeptidase 13 (collagenase 3) like L homeolog (mmp13l.L) 抗体
  • cb1034 抗体
  • Clg 抗体
  • CLG3 抗体
  • gene A 抗体
  • MANDP1 抗体
  • MGC108008 抗体
  • MMP-13 抗体
  • Mmp1 抗体
  • MMP13 抗体
  • xcl3 抗体
  • xCol 抗体

Protein level used designations for MMP13

MMP-13 , collagenase 3 , matrix metalloproteinase 13 (collagenase 3) , Collagenase-3 , collagenase-1 , interstitial collagenase , matrix metalloproteinase 13 , matrix metalloproteinase-13 , UMRCASE , collagenase-3 , MMPLg , MMPLh , gene 11 , matrix metallopeptidase 13 (collagenase 3) , gene A , collagenase 3-like

GENE ID SPECIES
4322 Homo sapiens
17386 Mus musculus
171052 Rattus norvegicus
281914 Bos taurus
379552 Xenopus laevis
387293 Danio rerio
398056 Xenopus laevis
443113 Ovis aries
451513 Pan troglodytes
493679 Felis catus
613098 Xenopus (Silurana) tropicalis
703980 Macaca mulatta
100008685 Oryctolagus cuniculus
100009711 Equus caballus
100012553 Monodelphis domestica
100136348 Salmo salar
100396943 Callithrix jacchus
100462632 Pongo abelii
100526826 Ictalurus punctatus
100552256 Anolis carolinensis
100584961 Nomascus leucogenys
397346 Sus scrofa
397823 Xenopus laevis
395683 Gallus gallus
403763 Canis lupus familiaris
100731756 Cavia porcellus
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